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Gary Lopaschuk
Gary Lopaschuk
Professor, Pediatrics, Universit of Alberta
Adresse e-mail validée de ualberta.ca
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Myocardial substrate metabolism in the normal and failing heart
WC Stanley, FA Recchia, GD Lopaschuk
Physiological reviews 85 (3), 1093-1129, 2005
25072005
Myocardial fatty acid metabolism in health and disease
GD Lopaschuk, JR Ussher, CDL Folmes, JS Jaswal, WC Stanley
Physiological reviews 90 (1), 207-258, 2010
23262010
Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance
TR Koves, JR Ussher, RC Noland, D Slentz, M Mosedale, O Ilkayeva, ...
Cell metabolism 7 (1), 45-56, 2008
21252008
A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth
S Bonnet, SL Archer, J Allalunis-Turner, A Haromy, C Beaulieu, ...
Cancer cell 11 (1), 37-51, 2007
19242007
The antianginal drug trimetazidine shifts cardiac energy metabolism from fatty acid oxidation to glucose oxidation by inhibiting mitochondrial long-chain 3-ketoacyl coenzyme A …
PF Kantor, A Lucien, R Kozak, GD Lopaschuk
Circulation research 86 (5), 580-588, 2000
15422000
The cardiac phenotype induced by PPARα overexpression mimics that caused by diabetes mellitus
BN Finck, JJ Lehman, TC Leone, MJ Welch, MJ Bennett, A Kovacs, X Han, ...
The Journal of clinical investigation 109 (1), 121-130, 2002
11952002
Regulation of myocardial carbohydrate metabolism under normal and ischaemic conditions: potential for pharmacological interventions
WC Stanley, GD Lopaschuk, JL Hall, JG McCormack
Cardiovascular research 33 (2), 243-257, 1997
9631997
Cardiovascular remodelling in coronary artery disease and heart failure
G Heusch, P Libby, B Gersh, D Yellon, M Böhm, G Lopaschuk, L Opie
The Lancet 383 (9932), 1933-1943, 2014
8322014
Regulation of fatty acid oxidation in the mammalian heart in health and disease
GD Lopaschuk, DD Belke, J Gamble, I Toshiyuki, BO Schönekess
Biochimica et Biophysica Acta (BBA)-Lipids and Lipid Metabolism 1213 (3 …, 1994
8001994
High rates of fatty acid oxidation during reperfusion of ischemic hearts are associated with a decrease in malonyl-CoA levels due to an increase in 5’-AMP-activated protein …
N Kudo, AJ Barr, RL Barr, S Desai, GD Lopaschuk
Journal of Biological Chemistry 270 (29), 17513-17520, 1995
7401995
Contribution of oxidative metabolism and glycolysis to ATP production in hypertrophied hearts
MF Allard, BO Schonekess, SL Henning, DR English, GD Lopaschuk
American Journal of Physiology-Heart and Circulatory Physiology 267 (2 …, 1994
7151994
Regulation of energy substrate metabolism in the diabetic heart
WC Stanley, GD Lopaschuk, JG McCormack
Cardiovascular research 34 (1), 25-33, 1997
6441997
Energy metabolic phenotype of the cardiomyocyte during development, differentiation, and postnatal maturation
GD Lopaschuk, JS Jaswal
Journal of cardiovascular pharmacology 56 (2), 130-140, 2010
6372010
Mechanisms of cardiovascular benefits of sodium glucose co-transporter 2 (SGLT2) inhibitors: a state-of-the-art review
GD Lopaschuk, S Verma
Basic to Translational Science 5 (6), 632-644, 2020
5592020
Cardiac energy metabolism in heart failure
GD Lopaschuk, QG Karwi, R Tian, AR Wende, ED Abel
Circulation research 128 (10), 1487-1513, 2021
5292021
Myocardial triglyceride turnover and contribution to energy substrate utilization in isolated working rat hearts
M Saddik, GD Lopaschuk
Journal of Biological Chemistry 266 (13), 8162-8170, 1991
5051991
AMPK alterations in cardiac physiology and pathology: enemy or ally?
JRB Dyck, GD Lopaschuk
The Journal of physiology 574 (1), 95-112, 2006
4802006
Pathways and control of ketone body metabolism: on the fringe of lipid biochemistry
T Fukao, GD Lopaschuk, GA Mitchell
Prostaglandins, leukotrienes and essential fatty acids 70 (3), 243-251, 2004
4772004
Mitochondrial fatty acid oxidation alterations in heart failure, ischaemic heart disease and diabetic cardiomyopathy
N Fillmore, J Mori, GD Lopaschuk
British journal of pharmacology 171 (8), 2080-2090, 2014
4682014
Targeting fatty acid and carbohydrate oxidation—a novel therapeutic intervention in the ischemic and failing heart
JS Jaswal, W Keung, W Wang, JR Ussher, GD Lopaschuk
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1813 (7), 1333-1350, 2011
4682011
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