| Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB DD Sarbassov, SM Ali, S Sengupta, JH Sheen, PP Hsu, AF Bagley, ... Molecular cell 22 (2), 159-168, 2006 | 3270 | 2006 |
| Regulation of the mTOR complex 1 pathway by nutrients, growth factors, and stress S Sengupta, TR Peterson, DM Sabatini Molecular cell 40 (2), 310-322, 2010 | 1526 | 2010 |
| mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway TR Peterson, SS Sengupta, TE Harris, AE Carmack, SA Kang, E Balderas, ... Cell 146 (3), 408-420, 2011 | 1309 | 2011 |
| p63 and p73 are required for p53-dependent apoptosis in response to DNA damage ER Flores, KY Tsai, D Crowley, S Sengupta, A Yang, F McKeon, T Jacks Nature 416 (6880), 560-564, 2002 | 1044 | 2002 |
| mTORC1 in the Paneth cell niche couples intestinal stem-cell function to calorie intake ÖH Yilmaz, P Katajisto, DW Lamming, Y Gültekin, KE Bauer-Rowe, ... Nature 486 (7404), 490-495, 2012 | 768 | 2012 |
| mTORC1 controls fasting-induced ketogenesis and its modulation by ageing S Sengupta, TR Peterson, M Laplante, S Oh, DM Sabatini Nature 468 (7327), 1100-1104, 2010 | 677 | 2010 |
| Tumor predisposition in mice mutant for p63 and p73: Evidence for broader tumor suppressor functions for the p53 family ER Flores, S Sengupta, JB Miller, JJ Newman, R Bronson, D Crowley, ... Cancer cell 7 (4), 363-373, 2005 | 636 | 2005 |
| Uropathogenic Escherichia coliPotentiates Type 1 Pilus-Induced Apoptosis by Suppressing NF-κB DJ Klumpp, AC Weiser, S Sengupta, SG Forrestal, RA Batler, ... Infection and immunity 69 (11), 6689-6695, 2001 | 192 | 2001 |
| Uropathogenic Escherichia coli induces extrinsic and intrinsic cascades to initiate urothelial apoptosis DJ Klumpp, MT Rycyk, MC Chen, P Thumbikat, S Sengupta, AJ Schaeffer Infection and immunity 74 (9), 5106-5113, 2006 | 126 | 2006 |
| Mast cell activation triggers a urothelial inflammatory response mediated by tumor necrosis factor-α RA Batler, S Sengupta, SG Forrestal, AJ Schaeffer, DJ Klumpp The Journal of urology 168 (2), 819-825, 2002 | 59 | 2002 |
| Discovery of NV-5138, the first selective Brain mTORC1 activator S Sengupta, E Giaime, S Narayan, S Hahm, J Howell, D o’Neill, ... Scientific reports 9 (1), 4107, 2019 | 53 | 2019 |
| Genome-scale RNAi on living-cell microarrays identifies novel regulators of Drosophila melanogaster TORC1–S6K pathway signaling RA Lindquist, KA Ottina, DB Wheeler, PP Hsu, CC Thoreen, DA Guertin, ... Genome research 21 (3), 433-446, 2011 | 48 | 2011 |
| Discovery of small-molecule selective mTORC1 inhibitors via direct inhibition of glucose transporters SA Kang, DJ O'Neill, AW Machl, CJ Lumpkin, SN Galda, S Sengupta, ... Cell chemical biology 26 (9), 1203-1213. e13, 2019 | 35 | 2019 |
| Modulators of sestrin-GATOR2 interaction and uses thereof KM Fetalvero, S Narayan, DJ O'neill, E Saiah, S Sengupta US Patent 10,100,066, 2018 | 8 | 2018 |
| Infectious response to E. coli: molecular and genetic pathways AJ Schaeffer, DJ Klumpp, AC Weiser, S Sengupta, SG Forrestal, ... International journal of antimicrobial agents 24, 57-60, 2004 | 6 | 2004 |
| METHODS OF IDENTIFYING MODULATORS OF SESTRIN-GATOR-2 INTERACTION AND USE OF SAME TO MODULATE mTORC1 DM Sabatini, L Chantranupong, RL Wolfson, J Orozco, RA Saxton, ... US Patent App. 15/511,007, 2017 | 3* | 2017 |
| Modulators of sestrin-GATOR2 interaction and uses thereof KM Fetalvero, S Narayan, DJ O'Neill, E Saiah, S Sengupta US Patent App. 10/100,066, 2018 | 1* | 2018 |
| mTORC1 regulates lipin I localization to control nuclear structure and the SREBP pathway TR Peterson, S Sengupta, E Harris, A Guertin BS Biochemistry, 42, 2010 | | 2010 |
| The role of mammalian target of rapamycin complex 1 in hepatic physiology and disease S Sengupta Massachusetts Institute of Technology, 2010 | | 2010 |
| Mast cell activation triggers a urothelial inflammatory response mediated by TNF-alpha RA Batler, S Sengupta, SG Forrestal, AJ Schaeffer, DJ Klumpp JOURNAL OF UROLOGY 167 (4), 6-7, 2002 | | 2002 |
David M. SabatiniInstitute of Organic Chemistry and Biochemistry of the CASVerified email at uochb.cas.cz
