New pharmacological strategies for treatment of Alzheimer's disease: focus on disease modifying drugs S Salomone, F Caraci, GM Leggio, J Fedotova, F Drago British journal of clinical pharmacology 73 (4), 504-517, 2012 | 413 | 2012 |
Anxiolytic effects in mice of a dual blocker of fatty acid amide hydrolase and transient receptor potential vanilloid type-1 channels V Micale, L Cristino, A Tamburella, S Petrosino, GM Leggio, F Drago, ... Neuropsychopharmacology 34 (3), 593-606, 2009 | 225 | 2009 |
Eriodictyol prevents early retinal and plasma abnormalities in streptozotocin-induced diabetic rats C Bucolo, GM Leggio, F Drago, S Salomone Biochemical pharmacology 84 (1), 88-92, 2012 | 164 | 2012 |
Dopamine D3 receptor as a new pharmacological target for the treatment of depression GM Leggio, S Salomone, C Bucolo, C Platania, V Micale, F Caraci, ... European journal of pharmacology 719 (1-3), 25-33, 2013 | 161 | 2013 |
Neurobiological links between depression and AD: the role of TGF-β1 signaling as a new pharmacological target F Caraci, SF Spampinato, MG Morgese, F Tascedda, MG Salluzzo, ... Pharmacological research 130, 374-384, 2018 | 154 | 2018 |
Current drug treatments targeting dopamine D3 receptor GM Leggio, C Bucolo, CBM Platania, S Salomone, F Drago Pharmacology & therapeutics 165, 164-177, 2016 | 122 | 2016 |
Dopamine outside the brain: The eye, cardiovascular system and endocrine pancreas C Bucolo, GM Leggio, F Drago, S Salomone Pharmacology & Therapeutics 203, 107392, 2019 | 115 | 2019 |
The PKCβ/HuR/VEGF pathway in diabetic retinopathy M Amadio, C Bucolo, GM Leggio, F Drago, S Govoni, A Pascale Biochemical pharmacology 80 (8), 1230-1237, 2010 | 115 | 2010 |
Molecular features of interaction between VEGFA and anti-angiogenic drugs used in retinal diseases: a computational approach CBM Platania, L Di Paola, GM Leggio, GL Romano, F Drago, S Salomone, ... Frontiers in pharmacology 6, 248, 2015 | 106 | 2015 |
Nanosystems based on siRNA silencing HuR expression counteract diabetic retinopathy in rat M Amadio, A Pascale, S Cupri, R Pignatello, C Osera, GM Leggio, ... Pharmacological research 111, 713-720, 2016 | 94 | 2016 |
Homology Modeling of Dopamine D2 and D3 Receptors: Molecular Dynamics Refinement and Docking Evaluation CBM Platania, S Salomone, GM Leggio, F Drago, C Bucolo Public Library of Science 7 (9), e44316, 2012 | 91 | 2012 |
Polyphenols and neuroprotection: Therapeutic implications for cognitive decline G Caruso, SA Torrisi, MP Mogavero, W Currenti, S Castellano, J Godos, ... Pharmacology & Therapeutics 232, 108013, 2022 | 84 | 2022 |
Dopamine D3 receptor is necessary for ethanol consumption: an approach with buspirone GM Leggio, G Camillieri, C Platania, A Castorina, G Marrazzo, SA Torrisi, ... Neuropsychopharmacology 39 (8), 2017-2028, 2014 | 84 | 2014 |
The dual blocker of FAAH/TRPV1 N-arachidonoylserotonin reverses the behavioral despair induced by stress in rats and modulates the HPA-axis A Navarria, A Tamburella, FA Iannotti, V Micale, G Camillieri, L Gozzo, ... Pharmacological research 87, 151-159, 2014 | 82 | 2014 |
Dopamine: an immune transmitter ST Broome, K Louangaphay, KA Keay, GM Leggio, G Musumeci, ... Neural regeneration research 15 (12), 2173-2185, 2020 | 81 | 2020 |
P2X7 receptor antagonism: Implications in diabetic retinopathy CBM Platania, G Giurdanella, L Di Paola, GM Leggio, F Drago, ... Biochemical pharmacology 138, 130-139, 2017 | 81 | 2017 |
Fluoxetine and Vortioxetine Reverse Depressive-Like Phenotype and Memory Deficits Induced by Aβ1-42 Oligomers in Mice: A Key Role of Transforming Growth … SA Torrisi, F Geraci, MR Tropea, M Grasso, G Caruso, A Fidilio, N Musso, ... Frontiers in Pharmacology 10, 693, 2019 | 66 | 2019 |
Behavioral effects of the β3 adrenoceptor agonist SR58611A: Is it the putative prototype of a new class of antidepressant/anxiolytic drugs? D Consoli, GM Leggio, C Mazzola, V Micale, F Drago European journal of pharmacology 573 (1-3), 139-147, 2007 | 66 | 2007 |
Aflibercept regulates retinal inflammation elicited by high glucose via the PlGF/ERK pathway F Lazzara, A Fidilio, CBM Platania, G Giurdanella, S Salomone, ... Biochemical pharmacology 168, 341-351, 2019 | 63 | 2019 |
Enhanced cognitive performance of dopamine D3 receptor “knock-out” mice in the step-through passive-avoidance test: assessing the role of the endocannabinoid/endovanilloid systems V Micale, L Cristino, A Tamburella, S Petrosino, GM Leggio, V Di Marzo, ... Pharmacological Research 61 (6), 531-536, 2010 | 62 | 2010 |