Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells J Lessard, G Sauvageau nature 423 (6937), 255-260, 2003 | 1911 | 2003 |
HOXB4-induced expansion of adult hematopoietic stem cells ex vivo J Antonchuk, G Sauvageau, RK Humphries Cell 109 (1), 39-45, 2002 | 931 | 2002 |
Polycomb group proteins: multi-faceted regulators of somatic stem cells and cancer M Sauvageau, G Sauvageau Cell stem cell 7 (3), 299-313, 2010 | 832 | 2010 |
Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b E Kroon, J Krosl, U Thorsteinsdottir, S Baban, AM Buchberg, ... The EMBO journal, 1998 | 777 | 1998 |
Overexpression of HOXB4 in hematopoietic cells causes the selective expansion of more primitive populations in vitro and in vivo. G Sauvageau, U Thorsteinsdottir, CJ Eaves, HJ Lawrence, C Largman, ... Genes & development 9 (14), 1753-1765, 1995 | 770 | 1995 |
Differential expression of homeobox genes in functionally distinct CD34+ subpopulations of human bone marrow cells. G Sauvageau, PM Lansdorp, CJ Eaves, DE Hogge, WH Dragowska, ... Proceedings of the National Academy of Sciences 91 (25), 12223-12227, 1994 | 675 | 1994 |
Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal I Fares, J Chagraoui, Y Gareau, S Gingras, R Ruel, N Mayotte, E Csaszar, ... Science 345 (6203), 1509-1512, 2014 | 646 | 2014 |
Overexpression of the myeloid leukemia–associatedHoxa9 gene in bone marrow cells induces stem cell expansion U Thorsteinsdottir, A Mamo, E Kroon, L Jerome, J Bijl, HJ Lawrence, ... Blood, The Journal of the American Society of Hematology 99 (1), 121-129, 2002 | 457 | 2002 |
Mice Bearing a Targeted Interruption of the Homeobox Gene HOXA9 Have Defects in Myeloid, Erythroid, and Lymphoid Hematopoiesis HJ Lawrence, CD Helgason, G Sauvageau, S Fong, DJ Izon, ... Blood, The Journal of the American Society of Hematology 89 (6), 1922-1930, 1997 | 425 | 1997 |
Overexpression of HOXA10 in Murine Hematopoietic Cells Perturbs both Myeloid and Lymphoid Differentiation and Leads to Acute Myeloid Leukemia U Thorsteinsdottir, G Sauvageau, MR Hough, W Dragowska, ... Molecular and cellular biology 17 (1), 495-505, 1997 | 417 | 1997 |
In vitro expansion of hematopoietic stem cells by recombinant TAT-HOXB4 protein J Krosl, P Austin, N Beslu, E Kroon, RK Humphries, G Sauvageau Nature medicine 9 (11), 1428-1432, 2003 | 404 | 2003 |
HOXB4 overexpression mediates very rapid stem cell regeneration and competitive hematopoietic repopulation J Antonchuk, G Sauvageau, RK Humphries Experimental hematology 29 (9), 1125-1134, 2001 | 337 | 2001 |
Defining roles for HOX and MEIS1 genes in induction of acute myeloid leukemia U Thorsteinsdottir, E Kroon, L Jerome, F Blasi, G Sauvageau Molecular and cellular biology, 2001 | 331 | 2001 |
A key role for EZH2 and associated genes in mouse and human adult T-cell acute leukemia C Simon, J Chagraoui, J Krosl, P Gendron, B Wilhelm, S Lemieux, ... Genes & development 26 (7), 651-656, 2012 | 322 | 2012 |
The Role of HOX Homeobox Genes in Normal and Leukemic Hematopoiesis HJ Lawrence, G Sauvageau, RK Humphries, C Largman Stem cells 14 (3), 281-291, 1996 | 312 | 1996 |
Functional antagonism of the Polycomb-Group genes eed and Bmi1 in hemopoietic cell proliferation J Lessard, A Schumacher, U Thorsteinsdottir, M van Lohuizen, ... Genes & development 13 (20), 2691-2703, 1999 | 290 | 1999 |
NUP98–HOXA9 expression in hemopoietic stem cells induces chronic and acute myeloid leukemias in mice E Kroon, U Thorsteinsdottir, N Mayotte, T Nakamura, G Sauvageau The EMBO journal, 2001 | 285 | 2001 |
Loss of expression of the Hoxa-9 homeobox gene impairs the proliferation and repopulating ability of hematopoietic stem cells HJ Lawrence, J Christensen, S Fong, YL Hu, I Weissman, G Sauvageau, ... Blood 106 (12), 3988-3994, 2005 | 272 | 2005 |
In vitro and in vivo expansion of hematopoietic stem cells G Sauvageau, NN Iscove, RK Humphries Oncogene 23 (43), 7223-7232, 2004 | 264 | 2004 |
Overexpression of HOXB3 in hematopoietic cells causes defective lymphoid development and progressive myeloproliferation G Sauvageau, U Thorsteinsdottir, MR Hough, P Hugo, HJ Lawrence, ... Immunity 6 (1), 13-22, 1997 | 229 | 1997 |