|TNF-α is a critical negative regulator of type 1 immune activation during intracellular bacterial infection|
A Zganiacz, M Santosuosso, J Wang, T Yang, L Chen, M Anzulovic, ...
The Journal of clinical investigation 113 (3), 401-413, 2004
|Dendritic cells transduced with an adenoviral vector encoding a model tumor-associated antigen for tumor vaccination|
Y Wan, J Bramson, R Carter, F Graham, J Gauldie
Human gene therapy 8 (11), 1355-1363, 1997
|Adenovector-mediated gene delivery of interleukin-2 in metastatic breast cancer and melanoma: results of a phase 1 clinical trial|
AK Stewart, NJ Lassam, IC Quirt, DJ Bailey, LE Rotstein, M Krajden, ...
Gene Therapy 6 (3), 350-363, 1999
|Potentiating cancer immunotherapy using an oncolytic virus|
BW Bridle, KB Stephenson, JE Boudreau, S Koshy, N Kazdhan, ...
Molecular Therapy 18 (8), 1430-1439, 2010
|Antigen presentation by exosomes released from peptide-pulsed dendritic cells is not suppressed by the presence of active CTL|
L Luketic, J Delanghe, PT Sobol, P Yang, E Frotten, KL Mossman, ...
The Journal of Immunology 179 (8), 5024-5032, 2007
|Enabling topical immunization via microporation: a novel method for pain-free and needle-free delivery of adenovirus-based vaccines|
J Bramson, K Dayball, C Evelegh, YH Wan, D Page, A Smith
Gene therapy 10 (3), 251-260, 2003
|PHENOTYPE, FUNCTION, AND IN VIVO MIGRATION AND SURVIVAL OF ALLOGENEIC DENDRITIC CELL PROGENITORS GENETICALLY ENGINEERED TO EXPRESS TGF-β1, 2|
WC Lee, C Zhong, S Qian, Y Wan, J Gauldie, Z Mi, PD Robbins, ...
Transplantation 66 (12), 1810-1817, 1998
|Molecular cloning, characterization, and tissue distribution of rat lipopolysaccharide binding protein. Evidence for extrahepatic expression.|
GL Su, PD Freeswick, DA Geller, Q Wang, RA Shapiro, YH Wan, TR Billiar, ...
The Journal of Immunology 153 (2), 743-752, 1994
|Maraba virus as a potent oncolytic vaccine vector|
JG Pol, L Zhang, BW Bridle, KB Stephenson, J Rességuier, S Hanson, ...
Molecular Therapy 22 (2), 420-429, 2014
|Engineering dendritic cells to enhance cancer immunotherapy|
JE Boudreau, A Bonehill, K Thielemans, Y Wan
Molecular therapy 19 (5), 841-853, 2011
|Adenoviral vectors expressing lymphotactin and interleukin 2 or lymphotactin and interleukin 12 synergize to facilitate tumor regression in murine breast cancer models|
PCR Emtage, Y Wan, M Hitt, FL Graham, WJ Muller, A Zlotnik, J Gauldie
Human gene therapy 10 (5), 697-709, 1999
|Effects of stuffer DNA on transgene expression from helper-dependent adenovirus vectors|
RJ Parks, JL Bramson, Y Wan, CL Addison, FL Graham
Journal of virology 73 (10), 8027-8034, 1999
|Vesicular stomatitis virus as a novel cancer vaccine vector to prime antitumor immunity amenable to rapid boosting with adenovirus|
BW Bridle, JE Boudreau, BD Lichty, J Brunellière, K Stephenson, S Koshy, ...
Molecular Therapy 17 (10), 1814-1821, 2009
|HDAC inhibition suppresses primary immune responses, enhances secondary immune responses, and abrogates autoimmunity during tumor immunotherapy|
BW Bridle, L Chen, CG Lemay, JS Diallo, J Pol, A Nguyen, A Capretta, ...
Molecular Therapy 21 (4), 887-894, 2013
|The CD8+ T cell population elicited by recombinant adenovirus displays a novel partially exhausted phenotype associated with prolonged antigen presentation that nonetheless …|
TC Yang, J Millar, T Groves, N Grinshtein, R Parsons, S Takenaka, Y Wan, ...
The Journal of Immunology 176 (1), 200-210, 2006
|Induction of ErbB-2/neu-specific protective and therapeutic antitumor immunity using genetically modified dendritic cells: enhanced efficacy by cotransduction of gene encoding …|
Y Chen, P Emtage, Q Zhu, R Foley, W Muller, M Hitt, J Gauldie, Y Wan
Gene Therapy 8 (4), 316-323, 2001
|Synergy in induction of increased renal allograft survival after portal vein infusion of dendritic cells transduced to express TGFβ and IL-10, along with administration of CHO …|
RM Gorczynski, J Bransom, M Cattral, X Huang, J Lei, L Xiaorong, ...
Clinical Immunology 95 (3), 182-189, 2000
|A double recombinant adenovirus expressing the costimulatory molecule B7-1 (murine) and human IL-2 induces complete tumor regression in a murine breast adenocarcinoma model|
PCR Emtage, Y Wan, JL Bramson, FL Graham, J Gauldie
The Journal of Immunology 160 (5), 2531-2538, 1998
|Vaccination-induced autoimmune vitiligo is a consequence of secondary trauma to the skin|
C Lane, J Leitch, X Tan, J Hadjati, JL Bramson, Y Wan
Cancer research 64 (4), 1509-1514, 2004
|Adaptive antiviral immunity is a determinant of the therapeutic success of oncolytic virotherapy|
PT Sobol, JE Boudreau, K Stephenson, Y Wan, BD Lichty, KL Mossman
Molecular Therapy 19 (2), 335-344, 2011