Robert J Vanner
Robert J Vanner
Verified email at mail.utoronto.ca
Title
Cited by
Cited by
Year
Cancer stem cells: an evolving concept
LV Nguyen, R Vanner, P Dirks, CJ Eaves
Nature Reviews Cancer 12 (2), 133-143, 2012
11052012
Quiescent Sox2+ cells drive hierarchical growth and relapse in sonic hedgehog subgroup medulloblastoma
RJ Vanner, M Remke, M Gallo, HJ Selvadurai, F Coutinho, L Lee, ...
Cancer cell 26 (1), 33-47, 2014
2102014
Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy
X Lan, DJ Jrg, FMG Cavalli, LM Richards, LV Nguyen, RJ Vanner, ...
Nature 549 (7671), 227-232, 2017
2022017
TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma
M Remke, V Ramaswamy, J Peacock, DJH Shih, C Koelsche, ...
Acta neuropathologica 126 (6), 917-929, 2013
1392013
ASCL1 reorganizes chromatin to direct neuronal fate and suppress tumorigenicity of glioblastoma stem cells
NI Park, P Guilhamon, K Desai, RF McAdam, E Langille, M O’Connor, ...
Cell stem cell 21 (2), 209-224. e7, 2017
1012017
MLL5 orchestrates a cancer self-renewal state by repressing the histone variant H3. 3 and globally reorganizing chromatin
M Gallo, FJ Coutinho, RJ Vanner, T Gayden, SC Mack, A Murison, ...
Cancer cell 28 (6), 715-729, 2015
752015
A tumorigenic MLL-homeobox network in human glioblastoma stem cells
M Gallo, J Ho, FJ Coutinho, R Vanner, L Lee, R Head, EKM Ling, ...
Cancer research 73 (1), 417-427, 2013
652013
DNA hypermethylation within TERT promoter upregulates TERT expression in cancer
DD Lee, R Leo, M Komosa, M Gallo, CH Zhang, T Lipman, M Remke, ...
The Journal of clinical investigation 129 (1), 223-229, 2019
642019
Relapse-fated latent diagnosis subclones in acute B lineage leukemia are drug tolerant and possess distinct metabolic programs
SM Dobson, L Garca-Prat, RJ Vanner, J Wintersinger, E Waanders, Z Gu, ...
Cancer discovery 10 (4), 568-587, 2020
322020
Medulloblastoma arises from the persistence of a rare and transient Sox2+ granule neuron precursor
HJ Selvadurai, E Luis, K Desai, X Lan, MC Vladoiu, O Whitley, C Galvin, ...
Cell reports 31 (2), 107511, 2020
92020
Genetic analysis of B-cell acute lymphoblastic leukemia dissemination to the central nervous system identifies clonal selection and therapeutic vulnerability
R Vanner, SM Dobson, I Grandal, OI Gan, J McLeod, J Kennedy, V Voisin, ...
Blood 132 (Supplement 1), 1542-1542, 2018
12018
Relapse-Initiating Clones Preexisting at Diagnosis in B-Cell Acute Lymphoblastic Leukemia Help Predict Molecular Pathways of Relapse
L Garcia Prat, SM Dobson, M Chan-Seng-Yue, R Vanner, A Murison, ...
Blood 132 (Supplement 1), 915-915, 2018
12018
Genetic profiling of central nervous system dissemination of B-acute lymphoblastic leukemia reveals clonal selection and therapeutic vulnerability
RJ Vanner, SM Dobson, I Grandal, O Gan, J McLeod, J Kennedy, V Voisin, ...
Cancer Research 78 (13 Supplement), 5173-5173, 2018
12018
Abstract A25: Evolving functional heterogeneity in B-acute lymphoblastic leukemia
SM Dobson, R Vanner, E Waanders, J McLeod, OI Gan, Z Gu, ...
Cancer Research 76 (3 Supplement), A25-A25, 2016
12016
Linking Subclonal Genetic Diversity with Functional Heterogeneity Identifies Diagnosis Subclones Destined to Relapse
SM Dobson, E Waanders, R Vanner, OI Gan, J McLeod, I Grandal, ...
Blood, The Journal of the American Society of Hematology 128 (22), 605-605, 2016
2016
Defining the mode of medulloblastoma growth using the Ptch1 heterozygous mouse model
RJ Vanner
2015
0003. PRELIMINARY STUDY Rg3-NANOPARTICLES TREAT GLIOBLASTOMA CELLS
L Bie, Y Ju, Z Jin
Neuro-oncology 15 (suppl_1), 2013
2013
0137. QUIESCENT, THERAPY RESISTANT Sox2+ STEM CELLS PROPAGATE PATCHED1+/-MOUSE MEDULLOBLASTOMA
R Vanner, M Remke, T Aviv, L Lee, X Zhu, I Clarke, M Taylor, P Dirks
Neuro-oncology 15 (suppl_1), 2013
2013
Breaking Advances
RJ Vanner, M Remke, M Gallo, HJ Selvadurai, F Coutinho, L Lee
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Articles 1–19