Robert J Vanner
Robert J Vanner
Verified email at mail.utoronto.ca
Title
Cited by
Cited by
Year
Cancer stem cells: an evolving concept
LV Nguyen, R Vanner, P Dirks, CJ Eaves
Nature Reviews Cancer 12 (2), 133-143, 2012
11662012
Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy
X Lan, DJ Jrg, FMG Cavalli, LM Richards, LV Nguyen, RJ Vanner, ...
Nature 549 (7671), 227-232, 2017
2322017
Quiescent Sox2+ cells drive hierarchical growth and relapse in sonic hedgehog subgroup medulloblastoma
RJ Vanner, M Remke, M Gallo, HJ Selvadurai, F Coutinho, L Lee, ...
Cancer cell 26 (1), 33-47, 2014
2242014
TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma
M Remke, V Ramaswamy, J Peacock, DJH Shih, C Koelsche, ...
Acta neuropathologica 126 (6), 917-929, 2013
1502013
ASCL1 reorganizes chromatin to direct neuronal fate and suppress tumorigenicity of glioblastoma stem cells
NI Park, P Guilhamon, K Desai, RF McAdam, E Langille, M O’Connor, ...
Cell stem cell 21 (2), 209-224. e7, 2017
1142017
MLL5 orchestrates a cancer self-renewal state by repressing the histone variant H3. 3 and globally reorganizing chromatin
M Gallo, FJ Coutinho, RJ Vanner, T Gayden, SC Mack, A Murison, ...
Cancer cell 28 (6), 715-729, 2015
802015
DNA hypermethylation within TERT promoter upregulates TERT expression in cancer
DD Lee, R Leo, M Komosa, M Gallo, CH Zhang, T Lipman, M Remke, ...
The Journal of clinical investigation 129 (1), 223-229, 2019
762019
A tumorigenic MLL-homeobox network in human glioblastoma stem cells
M Gallo, J Ho, FJ Coutinho, R Vanner, L Lee, R Head, EKM Ling, ...
Cancer research 73 (1), 417-427, 2013
682013
Relapse-fated latent diagnosis subclones in acute B lineage leukemia are drug tolerant and possess distinct metabolic programs
SM Dobson, L Garca-Prat, RJ Vanner, J Wintersinger, E Waanders, Z Gu, ...
Cancer discovery 10 (4), 568-587, 2020
422020
Medulloblastoma arises from the persistence of a rare and transient Sox2+ granule neuron precursor
HJ Selvadurai, E Luis, K Desai, X Lan, MC Vladoiu, O Whitley, C Galvin, ...
Cell reports 31 (2), 107511, 2020
132020
Genetic analysis of B-cell acute lymphoblastic leukemia dissemination to the central nervous system identifies clonal selection and therapeutic vulnerability
R Vanner, SM Dobson, I Grandal, OI Gan, J McLeod, J Kennedy, V Voisin, ...
Blood 132, 1542, 2018
12018
Relapse-Initiating Clones Preexisting at Diagnosis in B-Cell Acute Lymphoblastic Leukemia Help Predict Molecular Pathways of Relapse
LG Prat, SM Dobson, M Chan-Seng-Yue, R Vanner, A Murison, ...
Blood 132, 915, 2018
12018
Genetic profiling of central nervous system dissemination of B-acute lymphoblastic leukemia reveals clonal selection and therapeutic vulnerability
RJ Vanner, SM Dobson, I Grandal, O Gan, J McLeod, J Kennedy, V Voisin, ...
Cancer Research 78 (13 Supplement), 5173-5173, 2018
12018
Abstract A25: Evolving functional heterogeneity in B-acute lymphoblastic leukemia
SM Dobson, R Vanner, E Waanders, J McLeod, OI Gan, Z Gu, ...
Cancer Research 76 (3 Supplement), A25-A25, 2016
12016
Linking Subclonal Genetic Diversity with Functional Heterogeneity Identifies Diagnosis Subclones Destined to Relapse
SM Dobson, E Waanders, R Vanner, OI Gan, J McLeod, I Grandal, ...
Blood 128 (22), 605, 2016
2016
Defining the mode of medulloblastoma growth using the Ptch1 heterozygous mouse model
RJ Vanner
University of Toronto (Canada), 2015
2015
0137. QUIESCENT, THERAPY RESISTANT Sox2+ STEM CELLS PROPAGATE PATCHED1+/-MOUSE MEDULLOBLASTOMA
R Vanner, M Remke, T Aviv, L Lee, X Zhu, I Clarke, M Taylor, P Dirks
Neuro-oncology 15 (suppl_1), 2013
2013
Breaking Advances
RJ Vanner, M Remke, M Gallo, HJ Selvadurai, F Coutinho, L Lee
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