| Cancer stem cells: an evolving concept LV Nguyen, R Vanner, P Dirks, CJ Eaves Nature Reviews Cancer 12 (2), 133-143, 2012 | 1364 | 2012 |
| Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy X Lan, DJ Jörg, FMG Cavalli, LM Richards, LV Nguyen, RJ Vanner, ... Nature 549 (7671), 227-232, 2017 | 420 | 2017 |
| Quiescent Sox2+ cells drive hierarchical growth and relapse in sonic hedgehog subgroup medulloblastoma RJ Vanner, M Remke, M Gallo, HJ Selvadurai, F Coutinho, L Lee, ... Cancer cell 26 (1), 33-47, 2014 | 307 | 2014 |
| ASCL1 reorganizes chromatin to direct neuronal fate and suppress tumorigenicity of glioblastoma stem cells NI Park, P Guilhamon, K Desai, RF McAdam, E Langille, M O’Connor, ... Cell stem cell 21 (2), 209-224. e7, 2017 | 216 | 2017 |
| TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma M Remke, V Ramaswamy, J Peacock, DJH Shih, C Koelsche, ... Acta neuropathologica 126, 917-929, 2013 | 199 | 2013 |
| DNA hypermethylation within TERT promoter upregulates TERT expression in cancer DD Lee, R Leao, M Komosa, M Gallo, CH Zhang, T Lipman, M Remke, ... The Journal of clinical investigation 129 (1), 223-229, 2019 | 182 | 2019 |
| MLL5 orchestrates a cancer self-renewal state by repressing the histone variant H3. 3 and globally reorganizing chromatin M Gallo, FJ Coutinho, RJ Vanner, T Gayden, SC Mack, A Murison, ... Cancer cell 28 (6), 715-729, 2015 | 108 | 2015 |
| A tumorigenic MLL-homeobox network in human glioblastoma stem cells M Gallo, J Ho, FJ Coutinho, R Vanner, L Lee, R Head, EKM Ling, ... Cancer research 73 (1), 417-427, 2013 | 97 | 2013 |
| Relapse-fated latent diagnosis subclones in acute B lineage leukemia are drug tolerant and possess distinct metabolic programs SM Dobson, L García-Prat, RJ Vanner, J Wintersinger, E Waanders, Z Gu, ... Cancer discovery 10 (4), 568-587, 2020 | 89 | 2020 |
| Medulloblastoma arises from the persistence of a rare and transient Sox2+ granule neuron precursor HJ Selvadurai, E Luis, K Desai, X Lan, MC Vladoiu, O Whitley, C Galvin, ... Cell reports 31 (2), 2020 | 42 | 2020 |
| Multiomic profiling of central nervous system leukemia identifies mRNA translation as a therapeutic target RJ Vanner, SM Dobson, OI Gan, J McLeod, EM Schoof, I Grandal, ... Blood cancer discovery 3 (1), 16-31, 2022 | 4 | 2022 |
| Relapse-initiating clones preexisting at diagnosis in B-cell acute lymphoblastic leukemia help predict molecular pathways of relapse L Garcia Prat, SM Dobson, M Chan-Seng-Yue, R Vanner, A Murison, ... Blood, The Journal of the American Society of Hematology 132 (Supplement 1 …, 2018 | 1 | 2018 |
| Genetic analysis of B-cell acute lymphoblastic leukemia dissemination to the central nervous system identifies clonal selection and therapeutic vulnerability R Vanner, SM Dobson, I Grandal, OI Gan, J McLeod, J Kennedy, V Voisin, ... Blood 132 (Supplement 1), 1542-1542, 2018 | 1 | 2018 |
| Relapse-initiating clones preexisting at diagnosis in B-cell acute lymphoblastic leukemia help predict molecular pathways of relapse LG Prat, SM Dobson, M Chan-Seng-Yue, R Vanner, A Murison, ... Blood 132, 915, 2018 | 1 | 2018 |
| Abstract A25: Evolving functional heterogeneity in B-acute lymphoblastic leukemia SM Dobson, R Vanner, E Waanders, J McLeod, OI Gan, Z Gu, ... Cancer Research 76 (3_Supplement), A25-A25, 2016 | 1 | 2016 |
| TET2 Deficiency Increases the Competitive Advantage of Hematopoietic Stem Cells through Upregulation of Thrombopoietin Receptor Signaling S Chan, Y Yang, S Cathelin, A Liu, A Subedi, A Maher, M Hosseini, ... | | 2024 |
| Somatic TET2 Mutations Prime the Immune System for Response to Immune Checkpoint Blockade R Vanner, AGX Zeng, M Chan-Seng-Yue, S Bansal, E Donato, L Jin, ... Blood 142, 2689, 2023 | | 2023 |
| Genetic profiling of central nervous system dissemination of B-acute lymphoblastic leukemia reveals clonal selection and therapeutic vulnerability RJ Vanner, SM Dobson, I Grandal, O Gan, J McLeod, J Kennedy, V Voisin, ... Cancer Research 78 (13_Supplement), 5173-5173, 2018 | | 2018 |
| Linking Subclonal Genetic Diversity with Functional Heterogeneity Identifies Diagnosis Subclones Destined to Relapse SM Dobson, E Waanders, R Vanner, OI Gan, J McLeod, I Grandal, ... Blood 128 (22), 605, 2016 | | 2016 |
| Defining the mode of medulloblastoma growth using the Ptch1 heterozygous mouse model RJ Vanner University of Toronto (Canada), 2015 | | 2015 |
