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Joseph Therriault
Joseph Therriault
McGill University, Department of Neurology & Neurosurgery
Verified email at mail.mcgill.ca
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Year
Blood phosphorylated tau 181 as a biomarker for Alzheimer's disease: a diagnostic performance and prediction modelling study using data from four prospective cohorts
TK Karikari, TA Pascoal, NJ Ashton, S Janelidze, AL Benedet, ...
The Lancet Neurology 19 (5), 422-433, 2020
8172020
Monoamine oxidase B inhibitor, selegiline, reduces 18F-THK5351 uptake in the human brain
KP Ng, TA Pascoal, S Mathotaarachchi, J Therriault, MS Kang, M Shin, ...
Alzheimer's research & therapy 9, 1-9, 2017
3302017
Microglial activation and tau propagate jointly across Braak stages
TA Pascoal, AL Benedet, NJ Ashton, MS Kang, J Therriault, M Chamoun, ...
Nature medicine 27 (9), 1592-1599, 2021
2952021
Differences between plasma and cerebrospinal fluid glial fibrillary acidic protein levels across the Alzheimer disease continuum
AL Benedet, M Milà-Alomà, A Vrillon, NJ Ashton, TA Pascoal, F Lussier, ...
JAMA neurology 78 (12), 1471-1483, 2021
2312021
Association of apolipoprotein E ε4 with medial temporal tau independent of amyloid-β
J Therriault, AL Benedet, TA Pascoal, S Mathotaarachchi, M Chamoun, ...
JAMA neurology 77 (4), 470-479, 2020
1902020
18F-MK-6240 PET for early and late detection of neurofibrillary tangles
TA Pascoal, J Therriault, AL Benedet, M Savard, FZ Lussier, M Chamoun, ...
Brain 143 (9), 2818-2830, 2020
1602020
In vivo quantification of neurofibrillary tangles with [18F]MK-6240
TA Pascoal, M Shin, MS Kang, M Chamoun, D Chartrand, ...
Alzheimer's research & therapy 10, 1-14, 2018
1482018
Mild behavioral impairment is associated with β‐amyloid but not tau or neurodegeneration in cognitively intact elderly individuals
FZ Lussier, TA Pascoal, M Chamoun, J Therriault, C Tissot, M Savard, ...
Alzheimer's & dementia 16 (1), 192-199, 2020
1242020
Biomarker modeling of Alzheimer’s disease using PET-based Braak staging
J Therriault, TA Pascoal, FZ Lussier, C Tissot, M Chamoun, G Bezgin, ...
Nature aging 2 (6), 526-535, 2022
1072022
Cerebrospinal fluid p-tau231 as an early indicator of emerging pathology in Alzheimer's disease
NJ Ashton, AL Benedet, TA Pascoal, TK Karikari, J Lantero-Rodriguez, ...
EBioMedicine 76, 2022
832022
Determining amyloid-β positivity using 18F-AZD4694 PET imaging
J Therriault, AL Benedet, TA Pascoal, M Savard, NJ Ashton, M Chamoun, ...
Journal of Nuclear Medicine 62 (2), 247-252, 2021
772021
Cerebrospinal fluid synaptosomal-associated protein 25 is a key player in synaptic degeneration in mild cognitive impairment and Alzheimer’s disease
H Zhang, J Therriault, MS Kang, KP Ng, TA Pascoal, P Rosa-Neto, ...
Alzheimer's research & therapy 10, 1-11, 2018
762018
Association of phosphorylated tau biomarkers with amyloid positron emission tomography vs tau positron emission tomography
J Therriault, M Vermeiren, S Servaes, C Tissot, NJ Ashton, AL Benedet, ...
JAMA neurology 80 (2), 188-199, 2023
682023
APOEε4 potentiates the relationship between amyloid-β and tau pathologies
J Therriault, AL Benedet, TA Pascoal, S Mathotaarachchi, M Savard, ...
Molecular psychiatry 26 (10), 5977-5988, 2021
672021
Plasma neurofilament light associates with Alzheimer's disease metabolic decline in amyloid‐positive individuals
AL Benedet, NJ Ashton, TA Pascoal, A Leuzy, S Mathotaarachchi, ...
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring 11 (1 …, 2019
672019
Stage-specific links between plasma neurofilament light and imaging biomarkers of Alzheimer’s disease
AL Benedet, A Leuzy, TA Pascoal, NJ Ashton, S Mathotaarachchi, ...
Brain 143 (12), 3793-3804, 2020
662020
Aβ-induced vulnerability propagates via the brain’s default mode network
TA Pascoal, S Mathotaarachchi, MS Kang, S Mohaddes, M Shin, AY Park, ...
Nature communications 10 (1), 2353, 2019
662019
Anosognosia predicts default mode network hypometabolism and clinical progression to dementia
J Therriault, KP Ng, TA Pascoal, S Mathotaarachchi, MS Kang, H Struyfs, ...
Neurology 90 (11), e932-e939, 2018
662018
Astrocyte reactivity influences amyloid-β effects on tau pathology in preclinical Alzheimer’s disease
B Bellaver, G Povala, PCL Ferreira, JP Ferrari-Souza, DT Leffa, ...
Nature medicine 29 (7), 1775-1781, 2023
632023
Astrocyte biomarker signatures of amyloid-β and tau pathologies in Alzheimer’s disease
JP Ferrari-Souza, PCL Ferreira, B Bellaver, C Tissot, YT Wang, DT Leffa, ...
Molecular psychiatry 27 (11), 4781-4789, 2022
602022
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