3-Bromopyruvate as inhibitor of tumour cell energy metabolism and chemopotentiator of platinum drugs LS Ihrlund, E Hernlund, O Khan, MC Shoshan Molecular oncology 2 (1), 94-101, 2008 | 166 | 2008 |
Geranylgeranyltransferase type I (GGTase-I) deficiency hyperactivates macrophages and induces erosive arthritis in mice OM Khan, MX Ibrahim, M Jonsson, C Karlsson, M Liu, AKM Sjogren, ... The Journal of clinical investigation 121 (2), 628-639, 2011 | 111 | 2011 |
Potentiation of chemotherapeutic drugs by energy metabolism inhibitors 2‐deoxyglucose and etomoxir E Hernlund, LS Ihrlund, O Khan, YO Ates, S Linder, T Panaretakis, ... International journal of cancer 123 (2), 476-483, 2008 | 107 | 2008 |
The deubiquitinase USP9X regulates FBW7 stability and suppresses colorectal cancer OM Khan, J Carvalho, B Spencer-Dene, R Mitter, D Frith, AP Snijders, ... The Journal of clinical investigation 128 (4), 1326-1337, 2018 | 90 | 2018 |
Protein prenylation restrains innate immunity by inhibiting Rac1 effector interactions MK Akula, MX Ibrahim, EG Ivarsson, OM Khan, IT Kumar, M Erlandsson, ... Nature communications 10 (1), 3975, 2019 | 62 | 2019 |
Targeting GGTase-I activates RHOA, increases macrophage reverse cholesterol transport, and reduces atherosclerosis in mice OM Khan, MK Akula, K Skålen, C Karlsson, M Ståhlman, SG Young, ... Circulation 127 (7), 782-790, 2013 | 51 | 2013 |
Loss of one copy of Zfp148 reduces lesional macrophage proliferation and atherosclerosis in mice by activating p53 VI Sayin, OM Khan, LE Pehlivanoglu, A Staffas, MX Ibrahim, A Asplund, ... Circulation research 115 (9), 781-789, 2014 | 48 | 2014 |
Proteasomal degradation of the tumour suppressor FBW7 requires branched ubiquitylation by TRIP12 OM Khan, J Almagro, JK Nelson, S Horswell, V Encheva, KS Keyan, ... Nature Communications 12 (1), 2043, 2021 | 28 | 2021 |
Inactivating GGTase-I reduces disease phenotypes in a mouse model of K-RAS-induced myeloproliferative disease AKM Sjogren, KME Andersson, O Khan, FJ Olofsson, C Karlsson, ... Leukemia 25 (1), 186-189, 2011 | 21 | 2011 |
Circulating exosomal immuno-oncological checkpoints and cytokines are potential biomarkers to monitor tumor response to anti-PD-1/PD-L1 therapy in non-small cell lung cancer … S Akbar, A Raza, R Mohsin, A Kanbour, S Qadri, A Parray, AR Zar Gul, ... Frontiers in Immunology 13, 1097117, 2023 | 11 | 2023 |
Degradation assessment of Mg-Incorporated 3D printed PLA scaffolds for biomedical applications F Ali, SN Kalva, KH Mroue, KS Keyan, Y Tong, OM Khan, M Koç Bioprinting 35, e00302, 2023 | 8 | 2023 |
FBXW7 tumor suppressor regulation by dualspecificity tyrosine-regulated kinase 2 R Jiménez-Izquierdo, R Morrugares, L Suanes-Cobos, A Correa-Sáez, ... Cell Death & Disease 14 (3), 202, 2023 | 5 | 2023 |
E3 Ubiquitin Ligase TRIP12 Controls Exit from Mitosis via Positive Regulation of MCL-1 in Response to Taxol KS Keyan, R Alanany, A Kohil, OM Khan Cancers 15 (2), 505, 2023 | 1 | 2023 |
Cancer genomics in the era of precision medicine OM Khan, D Mallardo, J Decock Frontiers in Genetics 15, 1378917, 2024 | | 2024 |
Control of TGFβ signalling by ubiquitination independent function of E3 ubiquitin ligase TRIP12 KS Keyan, S Salim, S Gowda, D Abdelrahman, SS Amir, Z Islam, ... Cell Death & Disease 14 (10), 692, 2023 | | 2023 |
A small Rho GTPase RAB25 with a potential role in chemotherapy resistance in pancreatic cancer A Kohil, SS Amir, A Behrens, OM Khan Cancer Biomarkers 36 (2), 133-145, 2023 | | 2023 |