Marc Joseph Lajoie
Marc Joseph Lajoie
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Genomically Recoded Organisms Expand Biological Functions
MJ Lajoie, AJ Rovner, DB Goodman, HR Aerni, AD Haimovich, ...
Science 342 (6156), 357-360, 2013
Precise manipulation of chromosomes in vivo enables genome-wide codon replacement
FJ Isaacs, PA Carr, HH Wang, MJ Lajoie, B Sterling, L Kraal, AC Tolonen, ...
Science 333 (6040), 348-353, 2011
Biocontainment of genetically modified organisms by synthetic protein design
DJ Mandell, MJ Lajoie, MT Mee, R Takeuchi, G Kuznetsov, JE Norville, ...
Nature 518 (7537), 55-60, 2015
Design, synthesis, and testing toward a 57-codon genome
N Ostrov, M Landon, M Guell, G Kuznetsov, J Teramoto, N Cervantes, ...
Science 353 (6301), 819-822, 2016
The genome project-write
JD Boeke, G Church, A Hessel, NJ Kelley, A Arkin, Y Cai, R Carlson, ...
Science 353 (6295), 126-127, 2016
Lambda red recombineering in Escherichia coli occurs through a fully single-stranded intermediate
JA Mosberg, MJ Lajoie, GM Church
Genetics 186 (3), 791-799, 2010
Probing the Limits of Genetic Recoding in Essential Genes
MJ Lajoie, S Kosuri, JA Mosberg, CJ Gregg, D Zhang, GM Church
science 342 (6156), 361-363, 2013
Evolution of a designed protein assembly encapsulating its own RNA genome
GL Butterfield, MJ Lajoie, HH Gustafson, DL Sellers, U Nattermann, ...
Nature 552 (7685), 415-420, 2017
Enhanced multiplex genome engineering through co-operative oligonucleotide co-selection
PA Carr, HH Wang, B Sterling, FJ Isaacs, MJ Lajoie, G Xu, GM Church, ...
Nucleic Acids Research 40 (17), e132-e132, 2012
De novo design of bioactive protein switches
RA Langan, SE Boyken, AH Ng, JA Samson, G Dods, AM Westbrook, ...
Nature 572 (7768), 205-210, 2019
Improving Lambda Red Genome Engineering in Escherichia coli via Rational Removal of Endogenous Nucleases
JA Mosberg, CJ Gregg, MJ Lajoie, HH Wang, GM Church
PloS one 7 (9), e44638, 2012
Rewriting the genetic code
T Mukai, MJ Lajoie, M Englert, D Söll
Annual review of microbiology 71, 557-577, 2017
Codon usage of highly expressed genes affects proteome-wide translation efficiency
I Frumkin, MJ Lajoie, CJ Gregg, G Hornung, GM Church, Y Pilpel
Proceedings of the National Academy of Sciences 115 (21), E4940-E4949, 2018
An orthogonalized platform for genetic code expansion in both bacteria and eukaryotes
JS Italia, PS Addy, CJJ Wrobel, LA Crawford, MJ Lajoie, Y Zheng, ...
Nature Chemical Biology 13 (4), 446-450, 2017
Tricyclic compounds containing nonenolizable cyano enones. A novel class of highly potent anti-inflammatory and cytoprotective agents
T Honda, H Yoshizawa, C Sundararajan, E David, MJ Lajoie, ...
Journal of medicinal chemistry 54 (6), 1762-1778, 2011
Overcoming challenges in engineering the genetic code
MJ Lajoie, D Söll, GM Church
Journal of molecular biology 428 (5), 1004-1021, 2016
Emergent rules for codon choice elucidated by editing rare arginine codons in Escherichia coli
MG Napolitano, M Landon, CJ Gregg, MJ Lajoie, L Govindarajan, ...
Proceedings of the National Academy of Sciences 113 (38), E5588-E5597, 2016
Manipulating replisome dynamics to enhance lambda Red-mediated multiplex genome engineering
MJ Lajoie, CJ Gregg, JA Mosberg, GC Washington, GM Church
Nucleic acids research 40 (22), e170-e170, 2012
Rational optimization of tolC as a powerful dual selectable marker for genome engineering
CJ Gregg, MJ Lajoie, MG Napolitano, JA Mosberg, DB Goodman, J Aach, ...
Nucleic acids research 42 (7), 4779-4790, 2014
Multiplex pairwise assembly of array-derived DNA oligonucleotides
JC Klein, MJ Lajoie, JJ Schwartz, EM Strauch, J Nelson, D Baker, ...
Nucleic acids research 44 (5), e43-e43, 2016
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