Chai K. Lim
Chai K. Lim
Senior Research Fellow, Faculty of Medicine and Health Sciences, Macquarie University
Verified email at mq.edu.au - Homepage
TitleCited byYear
Characterization of the kynurenine pathway in human neurons
GJ Guillemin, KM Cullen, CK Lim, GA Smythe, B Garner, V Kapoor, ...
Journal of Neuroscience 27 (47), 12884-12892, 2007
2402007
Connecting inflammation with glutamate agonism in suicidality
S Erhardt, CK Lim, KR Linderholm, S Janelidze, D Lindqvist, ...
Neuropsychopharmacology 38 (5), 743, 2013
1942013
A role for inflammatory metabolites as modulators of the glutamate N-methyl-D-aspartate receptor in depression and suicidality
C Bay-Richter, KR Linderholm, CK Lim, M Samuelsson, ...
Brain, behavior, and immunity 43, 110-117, 2015
1612015
Quantitation of ATP-binding cassette subfamily-A transporter gene expression in primary human brain cells
WS Kim, GJ Guillemin, EN Glaros, CK Lim, B Garner
Neuroreport 17 (9), 891-896, 2006
1242006
Recent evidence for an expanded role of the kynurenine pathway of tryptophan metabolism in neurological diseases
MD Lovelace, B Varney, G Sundaram, MJ Lennon, CK Lim, K Jacobs, ...
Neuropharmacology 112, 373-388, 2017
992017
Antibodies to MOG have a demyelination phenotype and affect oligodendrocyte cytoskeleton
RC Dale, EM Tantsis, V Merheb, RYA Kumaran, N Sinmaz, ...
Neurology-Neuroimmunology Neuroinflammation 1 (1), e12, 2014
932014
Expression of tryptophan 2, 3-dioxygenase and production of kynurenine pathway metabolites in triple transgenic mice and human Alzheimer's disease brain
W Wu, JA Nicolazzo, L Wen, R Chung, R Stankovic, SS Bao, CK Lim, ...
PloS one 8 (4), e59749, 2013
862013
Involvement of the kynurenine pathway in human glioma pathophysiology
S Adams, C Teo, KL McDonald, A Zinger, S Bustamante, CK Lim, ...
PloS one 9 (11), e112945, 2014
742014
An enzyme in the kynurenine pathway that governs vulnerability to suicidal behavior by regulating excitotoxicity and neuroinflammation
L Brundin, CM Sellgren, CK Lim, J Grit, E Pålsson, M Landen, ...
Translational psychiatry 6 (8), e865, 2016
592016
NAD deficiency, congenital malformations, and niacin supplementation
H Shi, A Enriquez, M Rapadas, EMMA Martin, R Wang, J Moreau, CK Lim, ...
New England Journal of Medicine 377 (6), 544-552, 2017
552017
Kynurenine pathway metabolomics predicts and provides mechanistic insight into multiple sclerosis progression
CK Lim, A Bilgin, DB Lovejoy, V Tan, S Bustamante, BV Taylor, ...
Scientific reports 7, 41473, 2017
532017
Expression of the kynurenine pathway in human peripheral blood mononuclear cells: implications for inflammatory and neurodegenerative disease
SP Jones, NF Franco, B Varney, G Sundaram, DA Brown, J De Bie, ...
PloS one 10 (6), e0131389, 2015
522015
Understanding the roles of the kynurenine pathway in multiple sclerosis progression
CK Lim, BJ Brew, G Sundaram, GJ Guillemin
International Journal of Tryptophan Research 3, IJTR. S4294, 2010
492010
Current evidence for a role of the kynurenine pathway of tryptophan metabolism in multiple sclerosis
MD Lovelace, B Varney, G Sundaram, NF Franco, ML Ng, S Pai, CK Lim, ...
Frontiers in immunology 7, 246, 2016
472016
Understanding the role of the kynurenine pathway in human breast cancer immunobiology
B Heng, CK Lim, DB Lovejoy, A Bessede, L Gluch, GJ Guillemin
Oncotarget 7 (6), 6506, 2016
422016
Protection against hydrogen peroxide-mediated cytotoxicity in Friedreich's ataxia fibroblasts using novel iron chelators of the 2-pyridylcarboxaldehyde isonicotinoyl hydrazone …
CK Lim, DS Kalinowski, DR Richardson
Molecular pharmacology 74 (1), 225-235, 2008
422008
Involvement of the kynurenine pathway in the pathogenesis of Parkinson’s disease
CK Lim, FJ Fernandez-Gomez, N Braidy, C Estrada, C Costa, S Costa, ...
Progress in neurobiology 155, 76-95, 2017
402017
Does escitalopram reduce neurotoxicity in major depression?
A Halaris, AM Myint, V Savant, E Meresh, E Lim, G Guillemin, ...
Journal of psychiatric research 66, 118-126, 2015
392015
Altered kynurenine pathway metabolism in autism: Implication for immune‐induced glutamatergic activity
CK Lim, MM Essa, R de Paula Martins, DB Lovejoy, AA Bilgin, MI Waly, ...
Autism Research 9 (6), 621-631, 2016
372016
Activation of the kynurenine pathway and increased production of the excitotoxin quinolinic acid following traumatic brain injury in humans
EB Yan, T Frugier, CK Lim, B Heng, G Sundaram, M Tan, JV Rosenfeld, ...
Journal of neuroinflammation 12 (1), 110, 2015
372015
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