p53 inhibits CRISPR–Cas9 engineering in human pluripotent stem cells RJ Ihry, KA Worringer, MR Salick, E Frias, D Ho, K Theriault, S Kommineni, ... Nature Medicine, 2018 | 1002 | 2018 |
Genetic ablation of AXL does not protect human neural progenitor cells and cerebral organoids from Zika virus infection MF Wells, MR Salick, O Wiskow, DJ Ho, KA Worringer, RJ Ihry, ... Cell stem cell 19 (6), 703-708, 2016 | 289 | 2016 |
DRUG-seq for miniaturized high-throughput transcriptome profiling in drug discovery JJAK Chaoyang Ye, Daniel J. Ho, Marilisa Neri, Chian Yang, Tripti Kulkarni ... Nature Communications, 2018 | 164 | 2018 |
Genome-Scale CRISPR Screens Identify Human Pluripotency-Specific Genes Cell Reports 27 (2), 616-630, 2019 | 74 | 2019 |
Translational Control by the DEAD Box RNA Helicase belle Regulates Ecdysone-Triggered Transcriptional Cascades RJ Ihry, AL Sapiro, A Bashirullah PLoS genetics 8 (11), e1003085, 2012 | 47 | 2012 |
INO80-dependent regression of ecdysone-induced transcriptional responses regulates developmental timing in Drosophila SD Neuman, RJ Ihry, KM Gruetzmacher, A Bashirullah Developmental biology 387 (2), 229-239, 2014 | 22 | 2014 |
Genetic Control of Specificity to Steroid-Triggered Responses in Drosophila RJ Ihry, A Bashirullah Genetics 196 (3), 767-780, 2014 | 22 | 2014 |
DRUG-seq provides unbiased biological activity readouts for neuroscience drug discovery J Li, DJ Ho, M Henault, C Yang, M Neri, R Ge, S Renner, L Mansur, ... ACS Chemical Biology 17 (6), 1401-1414, 2022 | 15 | 2022 |
Genomic regions influencing gene expression of the HMW glutenins in wheat EW Storlie, RJ Ihry, LM Baehr, KA Tieszen, JH Engbers, ... Theoretical and Applied Genetics 118, 295-303, 2009 | 15 | 2009 |
Rapid Recombination Mapping for High-Throughput Genetic Screens in Drosophila AL Sapiro, RJ Ihry, DL Buhr, KM Konieczko, SM Ives, AK Engstrom, ... G3: Genes, Genomes, Genetics 3 (12), 2313-2319, 2013 | 10 | 2013 |
P53 toxicity is a hurdle to CRISPR RJ Ihry, KA Worringer, MR Salick, E Frias, D Ho, K Theriault, S Kommineni, ... CAS9 screening and engineering in human pluripotent stem cells. bioRxiv 168443, 2017 | 4 | 2017 |
DRUG-seq provides unbiased biological activity readouts for drug discovery J Li, DJ Ho, M Henault, C Yang, M Neri, R Ge, S Renner, L Mansur, ... Biorxiv, 2021.06. 07.447456, 2021 | 2 | 2021 |
Genome-Scale CRISPR Screening Identifies Novel Human Pluripotent Gene Networks bioRxiv, 2018 | 2 | 2018 |
Regulators of human pluripotent stem cells and uses thereof R Ihry, A Kaykas, M Hild WO Patent WO2019213276A9, 2018 | 2 | 2018 |
Patient Brain Organoids Identify a Link between the 16p11.2 Copy Number Variant and the RBFOX1 Gene. IRJ Kostic M, Raymond JJ, Freyre CAC, Henry B, Tumkaya T, Khlghatyan J ... ACS Chem Neurosci. 15 (14(22)), 3993-4012, 2023 | 1* | 2023 |
Methods and compositions for enhancing gene editing I Robert, A Kaykas, K Worringer US Patent App. 15/800,352, 2018 | 1 | 2018 |
Enhancing the Small-Scale Screenable Biological Space beyond Known Chemogenomics Libraries with Gray Chemical Matter─ Compounds with Novel Mechanisms from High-Throughput … JR Thomas, C Shelton IV, J Murphy, S Brittain, MA Bray, P Aspesi, ... ACS Chemical Biology 19 (4), 938-952, 2024 | | 2024 |
New insights from old data-Hunting for compounds with novel mechanisms using cellular high-throughput screening profiles with Grey Chemical Matter S Renner, J Thomas, C Shelton, S Brittain, MA Bray, P Aspesi Jr, ... | | 2023 |
New insights from old data-Hunting for compounds with novel mechanisms using cellular high-throughput screening profiles with Grey Chemical Matter JR Thomas, C Shelton IV, J Murphy, S Brittain, MA Bray, P Aspesi, ... | | 2023 |
TRAWLING: a Transcriptome Reference Aware of spLIciNG events ND Nanni, A Reyes, D Ho, R Ihry, A Kauffmann, EY Durand, A de Weck biorxiv, 2021.12. 03.471115, 2021 | | 2021 |