Matthew Sorbara
Matthew Sorbara
University of Guelph, MCB Department
Verified email at
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NOD proteins: regulators of inflammation in health and disease
DJ Philpott, MT Sorbara, SJ Robertson, K Croitoru, SE Girardin
Nature Reviews Immunology 14 (1), 9-23, 2014
Amino acid starvation induced by invasive bacterial pathogens triggers an innate host defense program
I Tattoli, MT Sorbara, D Vuckovic, A Ling, F Soares, LAM Carneiro, ...
Cell Host & Microbe 11 (6), 563-575, 2012
Functional and genomic variation between human-derived isolates of Lachnospiraceae reveals inter-and intra-species diversity
MT Sorbara, ER Littmann, E Fontana, TU Moody, CE Kohout, M Gjonbalaj, ...
Cell Host & Microbe 28 (1), 134-146. e4, 2020
Mitochondrial ROS fuel the inflammasome
MT Sorbara, SE Girardin
Cell research 21 (4), 558-560, 2011
Interbacterial mechanisms of colonization resistance and the strategies pathogens use to overcome them
MT Sorbara, EG Pamer
Mucosal immunology 12 (1), 1-9, 2019
Microbiome-based therapeutics
MT Sorbara, EG Pamer
Nature Reviews Microbiology, 1-16, 2022
The protein ATG16L1 suppresses inflammatory cytokines induced by the intracellular sensors Nod1 and Nod2 in an autophagy-independent manner
MT Sorbara, LK Ellison, M Ramjeet, LH Travassos, NL Jones, SE Girardin, ...
Immunity 39 (5), 858-873, 2013
Inhibiting antibiotic-resistant Enterobacteriaceae by microbiota-mediated intracellular acidification
MT Sorbara, K Dubin, ER Littmann, TU Moody, E Fontana, R Seok, ...
Journal of Experimental Medicine, jem. 20181639, 2019
Peptidoglycan: a critical activator of the mammalian immune system during infection and homeostasis
MT Sorbara, DJ Philpott
Immunological reviews 243 (1), 40-60, 2011
Listeria phospholipases subvert host autophagic defenses by stalling pre-autophagosomal structures
I Tattoli, MT Sorbara, C Yang, SA Tooze, DJ Philpott, SE Girardin
The EMBO journal 32 (23), 3066-3078, 2013
What is new with Nods?
JG Magalhaes, MT Sorbara, SE Girardin, DJ Philpott
Current opinion in immunology 23 (1), 29-34, 2011
Cellular aspects of Shigella pathogenesis: focus on the manipulation of host cell processes
SA Killackey, MT Sorbara, SE Girardin
Frontiers in cellular and infection microbiology 6, 38, 2016
Complement C3 drives autophagy-dependent restriction of cyto-invasive bacteria
MT Sorbara, EG Foerster, J Tsalikis, M Abdel-Nour, J Mangiapane, ...
Cell host & microbe 23 (5), 644-652. e5, 2018
Emerging themes in bacterial autophagy
MT Sorbara, SE Girardin
Current opinion in microbiology 23, 163-170, 2015
Rapid transcriptional and metabolic adaptation of intestinal microbes to host immune activation
S Becattini, MT Sorbara, SG Kim, EL Littmann, Q Dong, G Walsh, R Wright, ...
Cell Host & Microbe, 2021
Bacterial autophagy: The trigger, the target and the timing
I Tattoli, MT Sorbara, DJ Philpott, SE Girardin
Autophagy 8 (12), 1848-1850, 2012
Intracellular bacterial pathogens trigger the formation of U small nuclear RNA bodies (U bodies) through metabolic stress induction
J Tsalikis, I Tattoli, A Ling, MT Sorbara, DO Croitoru, DJ Philpott, ...
Journal of Biological Chemistry 290 (34), 20904-20918, 2015
Isoginkgetin, a natural biflavonoid proteasome inhibitor, sensitizes cancer cells to apoptosis via disruption of lysosomal homeostasis and impaired protein clearance
J Tsalikis, M Abdel-Nour, A Farahvash, MT Sorbara, S Poon, DJ Philpott, ...
Molecular and cellular biology 39 (10), 2019
A functional Wood‐Ljungdahl pathway devoid of a formate dehydrogenase in the gut acetogens Blautia wexlerae, Blautia luti and beyond
R Trischler, J Roth, MT Sorbara, X Schlegel, V Müller
Environmental Microbiology, 2022
Impact of Antibiotic-Resistant Bacteria on Immune Activation and Clostridioides difficile Infection in the Mouse Intestine
JW Keith, Q Dong, MT Sorbara, S Becattini, JK Sia, M Gjonbalaj, R Seok, ...
Infection and Immunity 88 (4), 2020
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