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Cynthia Guidos
Cynthia Guidos
Program in Developmental & Stem Cell Biology, Hospital for Sick Children Research Institute
Adresse e-mail validée de sickkids.ca - Page d'accueil
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Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia
LI Shlush, S Zandi, A Mitchel, WC Chen, JM Brandwein, V Gupta, ...
Nature 506 (7488), 328-33, 2014
16102014
Notch2-dependent classical dendritic cells orchestrate intestinal immunity to attaching-and-effacing bacterial pathogens
AT Satpathy, CG Briseño, JS Lee, D Ng, NA Manieri, W Kc, X Wu, ...
Nature immunology 14 (9), 937-948, 2013
4402013
Defective T-cell receptor signalling and positive selection of Vav-deficient CD4+CDS+thymocytes
KD Fischer, A Zmuidzinas, S Gardner, M Barbacid, A Bernstein, C Guidos
Nature 374 (6521), 474-476, 1995
3631995
V (D) J recombination activates a p53-dependent DNA damage checkpoint in scid lymphocyte precursors.
CJ Guidos, CJ Williams, I Grandal, G Knowles, MT Huang, JS Danska
Genes & development 10 (16), 2038-2054, 1996
3381996
Inactivation of Fac in mice produces inducible chromosomal instability and reduced fertility reminiscent of Fanconi anemia
M Chen, DJ Tomkins, W Auerbach, MK C, H Youssoufian, L Liu, O Gan, ...
Nature genetics 12 (4), 448-51, 1996
2901996
Fyn can partially substitute for Lck in T lymphocyte development
T Groves, P Smiley, MP Cooke, K Forbush, RM Perlmutter, CJ Guidos
Immunity 5 (5), 417-428, 1996
2851996
T cell receptor-mediated negative selection of autoreactive T lymphocyte precursors occurs after commitment to the CD4 or CD8 lineages.
CJ Guidos, JS Danska, CG Fathman, IL Weissman
The Journal of experimental medicine 172 (3), 835-845, 1990
2541990
Requirement for Notch1 signals at sequential early stages of intrathymic T cell development
JB Tan, I Visan, JS Yuan, CJ Guidos
Nature immunology 6 (7), 671-679, 2005
2462005
Subversion of the T/B lineage decision in the thymus by lunatic fringe-mediated inhibition of Notch-1
U Koch, TA Lacombe, D Holland, JL Bowman, BL Cohen, SE Egan, ...
Immunity 15 (2), 225-236, 2001
2392001
Notch signaling in development and disease
JA Harper, JS Yuan, JB Tan, I Visan, CJ Guidos
Clinical Genetics 64 (6), 461-472, 2003
2352003
Biochemical and Genetic Defects in the DNA-Dependent Protein Kinase in Murine scid Lymphocytes
JS Danska, DP Holland, S Mariathasan, KM Williams, CJ Guidos
Molecular and cellular biology 16 (10), 5507-5517, 1996
2351996
Functions of notch signaling in the immune system: consensus and controversies
JS Yuan, PC Kousis, S Suliman, I Visan, CJ Guidos
Annual review of immunology 28, 343-365, 2009
2252009
Intrathymic maturation of murine T lymphocytes from CD8+ precursors.
CJ GuIDOS, IL Weissman, B Adkins
Proceedings of the National Academy of Sciences 86 (19), 7542-7546, 1989
1851989
Zebrafish screen identifies novel compound with selective toxicity against leukemia
S Ridges, WL Heaton, D Joshi, H Choi, A Eiring, L Batchelor, P Choudhry, ...
Blood, The Journal of the American Society of Hematology 119 (24), 5621-5631, 2012
1682012
Notch signal strength controls cell fate in the haemogenic endothelium
L Gama-Norton, E Ferrando, C Ruiz-Herguido, Z Liu, J Guiu, AB Islam, ...
Nature communications 6 (1), 8510, 2015
1672015
Validation of CyTOF against flow cytometry for immunological studies and monitoring of human cancer clinical trials
R Gadalla, B Noamani, BL MacLeod, RJ Dickson, M Guo, W Xu, ...
Frontiers in oncology 9, 415, 2019
1632019
Lunatic and manic fringe cooperatively enhance marginal zone B cell precursor competition for delta-like 1 in splenic endothelial niches
JB Tan, K Xu, K Cretegny, I Visan, JS Yuan, SE Egan, CJ Guidos
Immunity 30 (2), 254-263, 2009
1532009
Characterization of a rat monoclonal antibody specific for a determinant encoded by the V beta 7 gene segment. Depletion of V beta 7+ T cells in mice with Mls-1a haplotype.
CY Okada, B Holzmann, C Guidos, E Palmer, IL Weissman
Journal of immunology (Baltimore, Md.: 1950) 144 (9), 3473-3477, 1990
1401990
Rescue of T cell-specific V (D) J recombination in SCID mice by DNA-damaging agents
JS Danska, F Pflumio, CJ Williams, O Huner, JE Dick, CJ Guidos
Science 266 (5184), 450-455, 1994
1381994
Lunatic fringe deficiency cooperates with the Met/Caveolin gene amplicon to induce basal-like breast cancer
K Xu, J Usary, PC Kousis, A Prat, DY Wang, JR Adams, W Wang, AJ Loch, ...
Cancer cell 21 (5), 626-641, 2012
1362012
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