Douglas Mahoney
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IAP-targeted therapies for cancer
EC LaCasse, DJ Mahoney, HH Cheung, S Plenchette, S Baird, ...
Oncogene 27 (48), 6252-6275, 2008
Noncanonical NF-κB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK
BJ Zarnegar, Y Wang, DJ Mahoney, PW Dempsey, HH Cheung, J He, ...
Nature immunology 9 (12), 1371-1378, 2008
Both cIAP1 and cIAP2 regulate TNFα-mediated NF-κB activation
DJ Mahoney, HH Cheung, RL Mrad, S Plenchette, C Simard, E Enwere, ...
Proceedings of the National Academy of Sciences 105 (33), 11778-11783, 2008
Analysis of global mRNA expression in human skeletal muscle during recovery from endurance exercise
DJ Mahoney, G Parise, S Melov, A Safdar, MA Tarnopolsky
The FASEB journal 19 (11), 1498-1500, 2005
Effect of creatine and weight training on muscle creatine and performance in vegetarians
DG Burke, PD Chilibeck, G Parise, DG Candow, D Mahoney, ...
Medicine & Science in Sports & Exercise 35 (11), 1946-1955, 2003
Beneficial effects of creatine, CoQ10, and lipoic acid in mitochondrial disorders
MC Rodriguez, JR MacDonald, DJ Mahoney, G Parise, MF Beal, ...
Muscle & nerve 35 (2), 235-242, 2007
Oxidative stress and the mitochondrial theory of aging in human skeletal muscle
P Gianni, KJ Jan, MJ Douglas, PM Stuart, MA Tarnopolsky
Experimental gerontology 39 (9), 1391-1400, 2004
Creatine monohydrate enhances strength and body composition in Duchenne muscular dystrophy
MA Tarnopolsky, DJ Mahoney, J Vajsar, C Rodriguez, TJ Doherty, ...
Neurology 62 (10), 1771-1777, 2004
Real-time RT-PCR analysis of housekeeping genes in human skeletal muscle following acute exercise
DJ Mahoney, K Carey, MH Fu, R Snow, D Cameron-Smith, G Parise, ...
Physiological genomics 18 (2), 226-231, 2004
Identification of genetically modified Maraba virus as an oncolytic rhabdovirus
J Brun, D McManus, C Lefebvre, K Hu, T Falls, H Atkins, JC Bell, ...
Molecular Therapy 18 (8), 1440-1449, 2010
Effects of high‐intensity endurance exercise training in the G93A mouse model of amyotrophic lateral sclerosis
DJ Mahoney, C Rodriguez, M Devries, N Yasuda, MA Tarnopolsky
Muscle & Nerve: Official Journal of the American Association of …, 2004
Smac mimetics and innate immune stimuli synergize to promote tumor death
ST Beug, VA Tang, EC LaCasse, HH Cheung, CE Beauregard, J Brun, ...
Nature biotechnology 32 (2), 182-190, 2014
Gene expression profiling in human skeletal muscle during recovery from eccentric exercise
DJ Mahoney, A Safdar, G Parise, S Melov, M Fu, L MacNeil, J Kaczor, ...
American Journal of Physiology-Regulatory, Integrative and Comparative …, 2008
Treadmill training–induced adaptations in muscle phenotype in persons with incomplete spinal cord injury
BG Stewart, MA Tarnopolsky, AL Hicks, N McCartney, DJ Mahoney, ...
Muscle & Nerve: Official Journal of the American Association of …, 2004
Virus-tumor interactome screen reveals ER stress response can reprogram resistant cancers for oncolytic virus-triggered caspase-2 cell death
DJ Mahoney, C Lefebvre, K Allan, J Brun, CA Sanaei, S Baird, N Pearce, ...
Cancer cell 20 (4), 443-456, 2011
Body-weight-support treadmill training improves blood glucose regulation in persons with incomplete spinal cord injury
SM Phillips, BG Stewart, DJ Mahoney, AL Hicks, N McCartney, JE Tang, ...
Journal of Applied Physiology 97 (2), 716-724, 2004
Short-term 17β-estradiol decreases glucose Ra but not whole body metabolism during endurance exercise
S Carter, S McKenzie, M Mourtzakis, DJ Mahoney, MA Tarnopolsky
Journal of Applied Physiology 90 (1), 139-146, 2001
Oxidative stress and antioxidant enzyme upregulation in SOD1‐G93A mouse skeletal muscle
DJ Mahoney, JJ Kaczor, J Bourgeois, N Yasuda, MA Tarnopolsky
Muscle & Nerve: Official Journal of the American Association of …, 2006
Creatine monohydrate supplementation does not increase muscle strength, lean body mass, or muscle phosphocreatine in patients with myotonic dystrophy type 1
M Tarnopolsky, D Mahoney, T Thompson, H Naylor, TJ Doherty
Muscle & Nerve: Official Journal of the American Association of …, 2004
Down-regulation of c-FLIP Enhances death of cancer cells by smac mimetic compound
HH Cheung, DJ Mahoney, EC LaCasse, RG Korneluk
Cancer research 69 (19), 7729-7738, 2009
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