| Crystallographic evidence for substrate-assisted catalysis in a bacterial β-hexosaminidase BL Mark, DJ Vocadlo, S Knapp, BL Triggs-Raine, SG Withers, ... Journal of Biological Chemistry 276 (13), 10330-10337, 2001 | 375 | 2001 |
| Crystal structure of human β-hexosaminidase B: understanding the molecular basis of Sandhoff and Tay–Sachs disease BL Mark, DJ Mahuran, MM Cherney, D Zhao, S Knapp, MNG James Journal of molecular biology 327 (5), 1093-1109, 2003 | 279 | 2003 |
| Crystallographic structure of human β-hexosaminidase A: interpretation of Tay-Sachs mutations and loss of GM2 ganglioside hydrolysis MJ Lemieux, BL Mark, MM Cherney, SG Withers, DJ Mahuran, ... Journal of molecular biology 359 (4), 913-929, 2006 | 221 | 2006 |
| Aspartate 313 in the Streptomyces plicatushexosaminidase plays a critical role in substrate-assisted catalysis by orienting the 2-acetamido group and stabilizing the transition … SJ Williams, BL Mark, DJ Vocadlo, MNG James, SG Withers Journal of Biological Chemistry 277 (42), 40055-40065, 2002 | 175 | 2002 |
| Crystal structure of the Middle East respiratory syndrome coronavirus (MERS-CoV) papain-like protease bound to ubiquitin facilitates targeted disruption of deubiquitinating … BA Bailey-Elkin, RCM Knaap, GG Johnson, TJ Dalebout, DK Ninaber, ... Journal of Biological Chemistry 289 (50), 34667-34682, 2014 | 159 | 2014 |
| Transactivation of programmed ribosomal frameshifting by a viral protein Y Li, EE Treffers, S Napthine, A Tas, L Zhu, Z Sun, S Bell, BL Mark, ... Proceedings of the National Academy of Sciences 111 (21), E2172-E2181, 2014 | 158 | 2014 |
| Deubiquitinase function of arterivirus papain-like protease 2 suppresses the innate immune response in infected host cells PB van Kasteren, BA Bailey-Elkin, TW James, DK Ninaber, C Beugeling, ... Proceedings of the National Academy of Sciences 110 (9), E838-E847, 2013 | 144 | 2013 |
| Small molecule inhibitors of a glycoside hydrolase attenuate inducible AmpC-mediated β-lactam resistance KA Stubbs, M Balcewich, BL Mark, DJ Vocadlo Journal of Biological Chemistry 282 (29), 21382-21391, 2007 | 139 | 2007 |
| Mutation of a gene essential for ribosome biogenesis, EMG1, causes Bowen-Conradi syndrome J Armistead, S Khatkar, B Meyer, BL Mark, N Patel, G Coghlan, ... The American Journal of Human Genetics 84 (6), 728-739, 2009 | 135 | 2009 |
| Synthesis and use of mechanism-based protein-profiling probes for retaining β-D-glucosaminidases facilitate identification of Pseudomonas aeruginosa NagZ KA Stubbs, A Scaffidi, AW Debowski, BL Mark, RV Stick, DJ Vocadlo Journal of the American Chemical Society 130 (1), 327-335, 2008 | 113 | 2008 |
| Structural basis for the removal of ubiquitin and interferon-stimulated gene 15 by a viral ovarian tumor domain-containing protease TW James, N Frias-Staheli, JP Bacik, JM Levingston Macleod, ... Proceedings of the National Academy of Sciences 108 (6), 2222-2227, 2011 | 111 | 2011 |
| Recent advances in GFP folding reporter and split-GFP solubility reporter technologies. Application to improving the folding and solubility of recalcitrant proteins from … S Cabantous, JD Pedelacq, BL Mark, C Naranjo, TC Terwilliger, ... Journal of structural and functional genomics 6, 113-119, 2005 | 104 | 2005 |
| Structure of arterivirus nsp4: the smallest chymotrypsin-like proteinase with an α/β C-terminal extension and alternate conformations of the oxyanion hole IH Barrette-Ng, KKS Ng, BL Mark, D Van Aken, MM Cherney, C Garen, ... Journal of Biological Chemistry 277 (42), 39960-39966, 2002 | 93 | 2002 |
| Inactivation of the Glycoside Hydrolase NagZ Attenuates Antipseudomonal β-Lactam Resistance in Pseudomonas aeruginosa A Asgarali, KA Stubbs, A Oliver, DJ Vocadlo, BL Mark Antimicrobial agents and chemotherapy 53 (6), 2274-2282, 2009 | 79 | 2009 |
| Structure and function of viral deubiquitinating enzymes BA Bailey-Elkin, RCM Knaap, M Kikkert, BL Mark Journal of molecular biology 429 (22), 3441-3470, 2017 | 78 | 2017 |
| Active site plasticity within the glycoside hydrolase NagZ underlies a dynamic mechanism of substrate distortion JP Bacik, GE Whitworth, KA Stubbs, DJ Vocadlo, BL Mark Chemistry & Biology 19 (11), 1471-1482, 2012 | 78 | 2012 |
| The β-lactamase gene regulator AmpR is a tetramer that recognizes and binds the D-Ala-D-Ala motif of its repressor UDP-N-acetylmuramic acid (MurNAc)-pentapeptide G Vadlamani, MD Thomas, TR Patel, LJ Donald, TM Reeve, J Stetefeld, ... Journal of biological chemistry 290 (5), 2630-2643, 2015 | 77 | 2015 |
| NagZ Inactivation Prevents and Reverts β-Lactam Resistance, Driven by AmpD and PBP 4 Mutations, in Pseudomonas aeruginosa L Zamorano, TM Reeve, L Deng, C Juan, B Moyá, G Cabot, DJ Vocadlo, ... Antimicrobial agents and chemotherapy 54 (9), 3557-3563, 2010 | 77 | 2010 |
| Structural and functional characterization of Streptomyces plicatus β-N-acetylhexosaminidase by comparative molecular modeling and site-directed mutagenesis BL Mark, GA Wasney, TJS Salo, AR Khan, Z Cao, PW Robbins, ... Journal of Biological Chemistry 273 (31), 19618-19624, 1998 | 77 | 1998 |
| Structural and functional characterization of Streptomyces plicatus β-N-acetylhexosaminidase by comparative molecular modeling and site-directed mutagenesis BL Mark, GA Wasney, TJS Salo, AR Khan, Z Cao, PW Robbins, ... Journal of Biological Chemistry 273 (31), 19618-19624, 1998 | 77 | 1998 |
