Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD G Hewitt, V Borel, S Segura-Bayona, T Takaki, P Ruis, R Bellelli, ... Molecular cell 81 (4), 767-783. e11, 2021 | 85 | 2021 |
Mechanistic insights into autoinhibition of the oncogenic chromatin remodeler ALC1 LC Lehmann, G Hewitt, S Aibara, A Leitner, E Marklund, SL Maslen, ... Molecular cell 68 (5), 847-859. e7, 2017 | 60 | 2017 |
DNA surface exploration and operator bypassing during target search E Marklund, B van Oosten, G Mao, E Amselem, K Kipper, A Sabantsev, ... Nature 583 (7818), 858-861, 2020 | 55 | 2020 |
New enzymatic and mass spectrometric methodology for the selective investigation of gut microbiota-derived metabolites C Ballet, MSP Correia, LP Conway, TL Locher, LC Lehmann, N Garg, ... Chemical science 9 (29), 6233-6239, 2018 | 46 | 2018 |
Structure and dynamics of the chromatin remodeler ALC1 bound to a PARylated nucleosome L Bacic, G Gaullier, A Sabantsev, LC Lehmann, K Brackmann, D Dimakou, ... Elife 10, e71420, 2021 | 23 | 2021 |
Mechanistic insights into regulation of the ALC1 remodeler by the nucleosome acidic patch LC Lehmann, L Bacic, G Hewitt, K Brackmann, A Sabantsev, G Gaullier, ... Cell reports 33 (12), 2020 | 23 | 2020 |
Structure-guided approach to site-specific fluorophore labeling of the lac repressor LacI K Kipper, N Eremina, E Marklund, S Tubasum, G Mao, LC Lehmann, J Elf, ... PLoS One 13 (6), e0198416, 2018 | 12 | 2018 |
Allosteric control of ALC1-catalyzed nucleosome remodeling LC Lehmann Acta Universitatis Upsaliensis, 2021 | | 2021 |