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Triggering the interferon antiviral response through an IKK-related pathway
S Sharma, BR TenOever, N Grandvaux, GP Zhou, R Lin, J Hiscott
Science 300 (5622), 1148-1151, 2003
Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation
R Lin, C Heylbroeck, PM Pitha, J Hiscott
Molecular and cellular biology 18 (5), 2986-2996, 1998
Interferon regulatory factors: the next generation
Y Mamane, C Heylbroeck, P Génin, M Algarté, MJ Servant, C LePage, ...
Gene 237 (1), 1-14, 1999
Transcriptional profiling of interferon regulatory factor 3 target genes: direct involvement in the regulation of interferon-stimulated genes
N Grandvaux, MJ Servant, B tenOever, GC Sen, S Balachandran, ...
Journal of virology 76 (11), 5532-5539, 2002
Regulation of IRF-3-dependent innate immunity by the papain-like protease domain of the severe acute respiratory syndrome coronavirus
SG Devaraj, N Wang, Z Chen, Z Chen, M Tseng, N Barretto, R Lin, ...
Journal of Biological Chemistry 282 (44), 32208-32221, 2007
Structural and functional analysis of interferon regulatory factor 3: localization of the transactivation and autoinhibitory domains
R Lin, Y Mamane, J Hiscott
Molecular and cellular biology 19 (4), 2465-2474, 1999
Essential role of interferon regulatory factor 3 in direct activation of RANTES chemokine transcription
R Lin, C Heylbroeck, P Genin, PM Pitha, J Hiscott
Molecular and cellular biology 19 (2), 959-966, 1999
The NEMO adaptor bridges the nuclear factor-κB and interferon regulatory factor signaling pathways
T Zhao, L Yang, Q Sun, M Arguello, DW Ballard, J Hiscott, R Lin
Nature immunology 8 (6), 592-600, 2007
Regulation of type I interferon gene expression by interferon regulatory factor-3
SL Schafer, R Lin, PA Moore, J Hiscott, PM Pitha
Journal of Biological Chemistry 273 (5), 2714-2720, 1998
Selective DNA binding and association with the CREB binding protein coactivator contribute to differential activation of alpha/beta interferon genes by interferon regulatory …
R Lin, P Génin, Y Mamane, J Hiscott
Molecular and Cellular Biology 20 (17), 6342-6353, 2000
The herpes simplex virus ICP0 RING finger domain inhibits IRF3-and IRF7-mediated activation of interferon-stimulated genes
R Lin, RS Noyce, SE Collins, RD Everett, KL Mossman
Journal of virology 78 (4), 1675-1684, 2004
Primary activation of interferon A and interferon B gene transcription by interferon regulatory factor 3
YT Juang, W Lowther, M Kellum, WC Au, R Lin, J Hiscott, PM Pitha
Proceedings of the National Academy of Sciences 95 (17), 9837-9842, 1998
Triggering the interferon response: the role of IRF-3 transcription factor
J Hiscott, P Pitha, P Genin, H Nguyen, C Heylbroeck, Y Mamane, ...
Journal of interferon & cytokine research 19 (1), 1-13, 1999
Multiple regulatory domains control IRF-7 activity in response to virus infection
R Lin, Y Mamane, J Hiscott
Journal of Biological Chemistry 275 (44), 34320-34327, 2000
Regulation of RANTES chemokine gene expression requires cooperativity between NF-κB and IFN-regulatory factor transcription factors
P Génin, M Algarté, P Roof, R Lin, J Hiscott
The Journal of Immunology 164 (10), 5352-5361, 2000
Dissociation of a MAVS/IPS-1/VISA/Cardif-IKKε molecular complex from the mitochondrial outer membrane by hepatitis C virus NS3-4A proteolytic cleavage
R Lin, J Lacoste, P Nakhaei, Q Sun, L Yang, S Paz, P Wilkinson, ...
Journal of virology 80 (12), 6072-6083, 2006
Identification of the minimal phosphoacceptor site required for in vivo activation of interferon regulatory factor 3 in response to virus and double-stranded RNA
MJ Servant, N Grandvaux, D Duguay, R Lin, J Hiscott
Journal of Biological Chemistry 278 (11), 9441-9447, 2003
Phosphorylation of IkappaBalpha in the C-terminal PEST domain by casein kinase II affects intrinsic protein stability
R Lin, P Beauparlant, C Makris, S Meloche, J Hiscott
Molecular and Cellular Biology, 1996
Negative regulation of the retinoic acid-inducible gene I-induced antiviral state by the ubiquitin-editing protein A20
R Lin, L Yang, P Nakhaei, Q Sun, E Sharif-Askari, I Julkunen, J Hiscott
Journal of Biological Chemistry 281 (4), 2095-2103, 2006
HHV-8 encoded vIRF-1 represses the interferon antiviral response by blocking IRF-3 recruitment of the CBP/p300 coactivators
R Lin, P Genin, Y Mamane, M Sgarbanti, A Battistini, WJ Harrington, ...
Oncogene 20 (7), 800-811, 2001
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