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Luca Laraia
Luca Laraia
Associate Professor, Technical University of Denmark
Verified email at kemi.dtu.dk - Homepage
Title
Cited by
Cited by
Year
Functionalised staple linkages for modulating the cellular activity of stapled peptides
YH Lau, P De Andrade, ST Quah, M Rossmann, L Laraia, N Sköld, ...
Chemical Science 5 (5), 1804-1809, 2014
2032014
Chemical genetics
CJ O'Connor, L Laraia, DR Spring
Chemical Society Reviews 40 (8), 4332-4345, 2011
1582011
Overcoming chemical, biological, and computational challenges in the development of inhibitors targeting protein-protein interactions
L Laraia, G McKenzie, DR Spring, AR Venkitaraman, DJ Huggins
Chemistry & biology 22 (6), 689-703, 2015
1562015
Principle and design of pseudo-natural products
G Karageorgis, DJ Foley, L Laraia, H Waldmann
Nature Chemistry 12 (3), 227-235, 2020
1522020
Diversity-oriented synthesis as a tool for identifying new modulators of mitosis
BM Ibbeson*, L Laraia*, E Alza, CJ O'Connor, YS Tan, HML Davies, ...
Nature Communications 5, 2014
912014
Stereoselective Synthesis of cis- and trans-2,3-Disubstituted Tetrahydrofurans via Oxonium−Prins Cyclization: Access to the Cordigol Ring System
AC Spivey, L Laraia, AR Bayly, HS Rzepa, AJP White
Organic letters 12 (5), 900-903, 2010
862010
Discovery of novel cinchona‐alkaloid‐inspired oxazatwistane autophagy inhibitors
L Laraia, K Ohsawa, G Konstantinidis, L Robke, YW Wu, K Kumar, ...
Angewandte Chemie International Edition 56 (8), 2145-2150, 2017
742017
Pseudo natural products—chemical evolution of natural product structure
G Karageorgis, DJ Foley, L Laraia, S Brakmann, H Waldmann
Angewandte Chemie International Edition 60 (29), 15705-15723, 2021
732021
New Prodigiosin Derivatives Obtained by Mutasynthesis in Pseudomonas putida
AS Klein, A Domröse, P Bongen, HUC Brass, T Classen, A Loeschcke, ...
ACS synthetic biology 6 (9), 1757-1765, 2017
712017
Synthesis of Indomorphan pseudo‐natural product inhibitors of glucose transporters GLUT‐1 and‐3
J Ceballos, M Schwalfenberg, G Karageorgis, ES Reckzeh, S Sievers, ...
Angewandte Chemie 131 (47), 17172-17181, 2019
642019
The cholesterol transfer protein GRAMD1A regulates autophagosome biogenesis
L Laraia, A Friese, DP Corkery, G Konstantinidis, N Erwin, W Hofer, ...
Nature chemical biology 15 (7), 710-720, 2019
642019
Highly Enantioselective Catalytic Vinylogous Propargylation of Coumarins Yields a Novel Autophagy Inhibitor Class
H Xu, L Laraia, L Schneider, K Louven, C Strohmann, AP Antonchick, ...
Angewandte Chemie International Edition, 2017
642017
Natural product inspired compound collections: evolutionary principle, chemical synthesis, phenotypic screening, and target identification
L Laraia, H Waldmann
Drug Discovery Today: Technologies 23, 75-82, 2017
632017
Phenotypic Identification of a Novel Autophagy Inhibitor Chemotype Targeting Lipid Kinase VPS34
L Robke, L Laraia, MA Carnero Corrales, G Konstantinidis, M Muroi, ...
Angewandte Chemie International Edition, 2017
622017
Small molecule probes for targeting autophagy
T Whitmarsh-Everiss, L Laraia
Nature chemical biology 17 (6), 653-664, 2021
562021
Synthesis and biological profiling of tellimagrandin I and analogues reveals that the medium ring can significantly modulate biological activity
S Zheng, L Laraia, CJ O'Connor, D Sorrell, YS Tan, Z Xu, ...
Organic & Biomolecular Chemistry 10 (13), 2590-2593, 2012
512012
Bioactive compound collections: from design to target identification
L Laraia, L Robke, H Waldmann
Chem 4 (4), 705-730, 2018
502018
Image‐based morphological profiling identifies a lysosomotropic, Iron‐sequestering autophagy inhibitor
L Laraia, G Garivet, DJ Foley, N Kaiser, S Müller, S Zinken, T Pinkert, ...
Angewandte Chemie International Edition 59 (14), 5721-5729, 2020
492020
Phenotyping reveals targets of a pseudo‐Natural‐product autophagy inhibitor
DJ Foley, S Zinken, D Corkery, L Laraia, A Pahl, YW Wu, H Waldmann
Angewandte Chemie International Edition 59 (30), 12470-12476, 2020
412020
Discovery of the novel autophagy inhibitor aumitin that targets mitochondrial complex I
L Robke, Y Futamura, G Konstantinidis, J Wilke, H Aono, Z Mahmoud, ...
Chemical science 9 (11), 3014-3022, 2018
332018
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Articles 1–20