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Ayesh K. Seneviratne, MD, PhD
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Lysosomal disruption preferentially targets acute myeloid leukemia cells and progenitors
MA Sukhai, S Prabha, R Hurren, AC Rutledge, AY Lee, ...
The Journal of clinical investigation 123 (1), 2012
1562012
The mitochondrial transacylase, tafazzin, regulates AML stemness by modulating intracellular levels of phospholipids
AK Seneviratne, M Xu, JJA Henao, VA Fajardo, Z Hao, V Voisin, GW Xu, ...
Cell stem cell 24 (4), 621-636. e16, 2019
522019
Disrupting mitochondrial copper distribution inhibits leukemic stem cell self-renewal
RP Singh, DV Jeyaraju, V Voisin, R Hurren, C Xu, JR Hawley, ...
Cell Stem Cell 26 (6), 926-937. e10, 2020
422020
Mitochondrial carrier homolog 2 is necessary for AML survival
DH Khan, M Mullokandov, Y Wu, V Voisin, M Gronda, R Hurren, X Wang, ...
Blood, The Journal of the American Society of Hematology 136 (1), 81-92, 2020
272020
Expansion of umbilical cord blood aldehyde dehydrogenase expressing cells generates myeloid progenitor cells that stimulate limb revascularization
DM Putman, TT Cooper, SE Sherman, AK Seneviratne, M Hewitt, GI Bell, ...
Stem cells translational medicine 6 (7), 1607-1619, 2017
272017
Expanded hematopoietic progenitor cells reselected for high aldehyde dehydrogenase activity demonstrate islet regenerative functions
AK Seneviratne, GI Bell, SE Sherman, TT Cooper, DM Putman, DA Hess
Stem Cells 34 (4), 873-887, 2016
162016
IPO11 regulates the nuclear import of BZW1/2 and is necessary for AML cells and stem cells
B Nachmias, DH Khan, V Voisin, AS Mer, GE Thomas, N Segev, ...
Leukemia 36 (5), 1283-1295, 2022
122022
Investigating microenvironmental regulation of human chordoma cell behaviour
P Patel, C Brooks, A Seneviratne, DA Hess, CA Séguin
PLoS One 9 (12), e115909, 2014
122014
Comorbidity profile of adult survivors at 20 years following allogeneic hematopoietic cell transplantation
AK Seneviratne, C Wright, W Lam, JH Lipton, FV Michelis
European Journal of Haematology 106 (2), 241-249, 2021
72021
Phospholipid metabolism regulates AML growth and stemness
M Xu, AK Seneviratne, AD Schimmer
Aging (Albany NY) 11 (12), 3895, 2019
52019
Tafazzin modulates cellular phospholipid composition to regulate AML stemness
AK Seneviratne, M Xu, AD Schimmer
Molecular & Cellular Oncology 6 (5), e1620051, 2019
42019
Transplantation Models to Characterize the Mechanisms of Stem Cell–Induced Islet Regeneration
GI Bell, AK Seneviratne, GN Nasri, DA Hess
Current Protocols in Stem Cell Biology 26 (1), 2B. 4.1-2B. 4.35, 2013
42013
Transduction of Primary AML Cells with Lentiviral Vector for In Vitro Study or In Vivo Engraftment
AD Schimmer, RP Singh, AK Seneviratne, GE Thomas, N MacLean, ...
STAR protocols 1 (3), 100163, 2020
12020
IPO11 is upregulated in relapsed AML and supports survival of leukemic stem cells
B Nachmias, V Voisin, R Hurren, X Wang, N Maclean, GW Xu, ...
Blood 134, 2530, 2019
12019
Addressing the need for a new generation of young translational researchers that focuses on societal impact: The Apollo Toronto Story
AK Seneviratne, SK Zahr, S Mirali, S Doshi, T Binesh Marvasti, ...
Clinical and Investigative Medicine 42 (3), E14-E16, 2019
12019
Development of a flood hazard zonation map for" Kalu Ganga" basin by GIS modelling
W Welivitiya, J Jayasingha, MK Musheen, SV Saputhanthri, ...
Department of Earth Resources Engineering, 2009
12009
Role of Tafazzin in Hematopoiesis and Leukemogenesis
A Seneviratne
University of Toronto (Canada), 2020
2020
Comorbidity profile of survivors at 20 years following allogeneic haematopoietic cell transplantation
AK Seneviratne, W Lam, JH Lipton, FV Michelis
BONE MARROW TRANSPLANTATION 54, 62-63, 2019
2019
Inhibiting the mitochondrial enzyme phosphatidylserine decarboxylase (PISD) reduces stemness and increases differentiation in acute myeloid leukemia (AML)
M Xu, A Seneviratne, VA Fajardo, GE Thomas, GW Xu, R Hurren, S Kim, ...
Cancer Research 79 (13_Supplement), 3003-3003, 2019
2019
Tafazzin (TAZ) Regulates the Differentiation of AML Cells By Reducing Levels of the Phospholipid Phosphatidylethanolamine
AK Seneviratne, JJA Henao, GW Xu, R Hurren, S Kim, N MacLean, ...
Blood 130, 788, 2017
2017
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Articles 1–20