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Nuala Ann Helsby
Nuala Ann Helsby
Associate Professor, University of Auckland
Verified email at auckland.ac.nz - Homepage
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Cited by
Year
The concise guide to pharmacology 2019/20: Enzymes
SPH Alexander, D Fabbro, E Kelly, A Mathie, JA Peters, EL Veale, ...
British Journal of Pharmacology 176, S297-S396, 2019
4972019
The concise guide to pharmacology 2021/22: Enzymes
SPH Alexander, D Fabbro, E Kelly, A Mathie, JA Peters, EL Veale, ...
British journal of pharmacology 178, S313-S411, 2021
3682021
The activation of the biguanide antimalarial proguanil co‐segregates with the mephenytoin oxidation polymorphism‐a panel study.
SA Ward, NA Helsby, E Skjelbo, K Brosen, LF Gram, AM Breckenridge
British journal of clinical pharmacology 31 (6), 689-692, 1991
1861991
The relative systemic availability of ivermectin after administration as capsule, tablet, and oral solution
G Edwards, A Dingsdale, N Helsby, MLE Orme, AM Breckenridge
European journal of clinical pharmacology 35, 681-684, 1988
1101988
2-Amino metabolites are key mediators of CB 1954 and SN 23862 bystander effects in nitroreductase GDEPT
NA Helsby, DM Ferry, AV Patterson, SM Pullen, WR Wilson
British journal of cancer 90 (5), 1084-1092, 2004
1082004
Quantitation of bystander effects in nitroreductase suicide gene therapy using three-dimensional cell cultures
WR Wilson, SM Pullen, A Hogg, NA Helsby, KO Hicks, WA Denny
Cancer Research 62 (5), 1425-1432, 2002
1042002
The pharmacokinetics and activation of proguanil in man: consequences of variability in drug metabolism.
NA Helsby, SA Ward, G Edwards, RE Howells, AM Breckenridge
British journal of clinical pharmacology 30 (4), 593-598, 1990
951990
Metabolomic analysis identifies inflammatory and noninflammatory metabolic effects of genetic modification in a mouse model of Crohn’s disease
HM Lin, MPG Barnett, NC Roy, NI Joyce, S Zhu, K Armstrong, NA Helsby, ...
Journal of proteome research 9 (4), 1965-1975, 2010
862010
Nontargeted urinary metabolite profiling of a mouse model of Crohn’s disease
HM Lin, SJ Edmunds, NA Helsby, LR Ferguson, DD Rowan
Journal of proteome research 8 (4), 2045-2057, 2009
832009
Effect of nitroreduction on the alkylating reactivity and cytotoxicity of the 2, 4-dinitrobenzamide-5-aziridine CB 1954 and the corresponding nitrogen mustard SN 23862 …
NA Helsby, SJ Wheeler, FB Pruijn, BD Palmer, S Yang, WA Denny, ...
Chemical research in toxicology 16 (4), 469-478, 2003
822003
Bystander effects of bioreductive drugs: potential for exploiting pathological tumor hypoxia with dinitrobenzamide mustards
WR Wilson, KO Hicks, SM Pullen, DM Ferry, NA Helsby, AV Patterson
Radiation research 167 (6), 625-636, 2007
752007
In vitro metabolism of the biguanide antimalarials in human liver microsomes: evidence for a role of the mephenytoin hydroxylase (P450 MP) enzyme.
NA Helsby, SA Ward, RE Howells, AM Breckenridge
British journal of clinical pharmacology 30 (2), 287-291, 1990
751990
Using metabolomic analysis to understand inflammatory bowel diseases
HM Lin, NA Helsby, DD Rowan, LR Ferguson
Inflammatory bowel diseases 17 (4), 1021-1029, 2011
712011
Metabolism of thalidomide in liver microsomes of mice, rabbits, and humans
J Lu, N Helsby, BD Palmer, M Tingle, BC Baguley, P Kestell, LM Ching
Journal of Pharmacology and Experimental Therapeutics 310 (2), 571-577, 2004
682004
Antimutagenic effects of wheat bran diet through modification of xenobiotic metabolising enzymes
NA Helsby, S Zhu, AE Pearson, MD Tingle, LR Ferguson
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 454 (1 …, 2000
672000
The combined impact of CYP2C19 and CYP2B6 pharmacogenetics on cyclophosphamide bioactivation
NA Helsby, CY Hui, MA Goldthorpe, JK Coller, MC Soh, PJ Gow, ...
British journal of clinical pharmacology 70 (6), 844-853, 2010
612010
CYP2C19 pharmacogenetics in advanced cancer: compromised function independent of genotype
NA Helsby, WY Lo, K Sharples, G Riley, M Murray, K Spells, M Dzhelai, ...
British journal of cancer 99 (8), 1251-1255, 2008
602008
Inhibition of mouse and human CYP 1A-and 2E1-dependent substrate metabolism by the isoflavonoids genistein and equol
NA Helsby, JK Chipman, A Gescher, D Kerr
Food and chemical toxicology 36 (5), 375-382, 1998
591998
Trypanocidal activity of aziridinyl nitrobenzamide prodrugs
C Bot, BS Hall, N Bashir, MC Taylor, NA Helsby, SR Wilkinson
Antimicrobial agents and chemotherapy 54 (10), 4246-4252, 2010
582010
The multiple dose pharmacokinetics of proguanil.
NA Helsby, G Edwards, AM Breckenridge, SA Ward
British journal of clinical pharmacology 35 (6), 653-656, 1993
521993
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