The spectrum kernel: A string kernel for SVM protein classification C Leslie, E Eskin, WS Noble Biocomputing 2002, 564-575, 2001 | 1266 | 2001 |
Comprehensive modeling of microRNA targets predicts functional non-conserved and non-canonical sites D Betel, A Koppal, P Agius, C Sander, C Leslie Genome biology 11 (8), R90, 2010 | 1186 | 2010 |
CSF-1R inhibition alters macrophage polarization and blocks glioma progression SM Pyonteck, L Akkari, AJ Schuhmacher, RL Bowman, L Sevenich, ... Nature medicine 19 (10), 1264, 2013 | 925 | 2013 |
Mismatch string kernels for discriminative protein classification CS Leslie, E Eskin, A Cohen, J Weston, WS Noble Bioinformatics 20 (4), 467-476, 2004 | 679 | 2004 |
Transfection of small RNAs globally perturbs gene regulation by endogenous microRNAs AA Khan, D Betel, ML Miller, C Sander, CS Leslie, DS Marks Nature biotechnology 27 (6), 549, 2009 | 467 | 2009 |
Mismatch string kernels for SVM protein classification E Eskin, J Weston, WS Noble, CS Leslie Advances in neural information processing systems, 1441-1448, 2003 | 359* | 2003 |
Genome-wide RNA-mediated interference screen identifies miR-19 targets in Notch-induced T-cell acute lymphoblastic leukaemia KJ Mavrakis, AL Wolfe, E Oricchio, T Palomero, K De Keersmaecker, ... Nature cell biology 12 (4), 372, 2010 | 331 | 2010 |
Foxp3 exploits a pre-existent enhancer landscape for regulatory T cell lineage specification RM Samstein, A Arvey, SZ Josefowicz, X Peng, A Reynolds, R Sandstrom, ... Cell 151 (1), 153-166, 2012 | 318 | 2012 |
Target mRNA abundance dilutes microRNA and siRNA activity A Arvey, E Larsson, C Sander, CS Leslie, DS Marks Molecular systems biology 6 (1), 2010 | 300 | 2010 |
Transcription factor Foxp3 and its protein partners form a complex regulatory network D Rudra, P Deroos, A Chaudhry, RE Niec, A Arvey, RM Samstein, ... Nature immunology 13 (10), 1010, 2012 | 296 | 2012 |
Genomic safe harbors permit high β-globin transgene expression in thalassemia induced pluripotent stem cells EP Papapetrou, G Lee, N Malani, M Setty, I Riviere, LMS Tirunagari, ... Nature biotechnology 29 (1), 73, 2011 | 295 | 2011 |
Semi-supervised protein classification using cluster kernels J Weston, D Zhou, A Elisseeff, WS Noble, CS Leslie Advances in neural information processing systems, 595-602, 2004 | 285 | 2004 |
Transcriptome-wide miR-155 binding map reveals widespread noncanonical microRNA targeting GB Loeb, AA Khan, D Canner, JB Hiatt, J Shendure, RB Darnell, ... Molecular cell 48 (5), 760-770, 2012 | 276 | 2012 |
Evaluation of methods for modeling transcription factor sequence specificity MT Weirauch, A Cote, R Norel, M Annala, Y Zhao, TR Riley, ... Nature biotechnology 31 (2), 126, 2013 | 267 | 2013 |
Profile-based string kernels for remote homology detection and motif extraction R Kuang, KE WANG, K Wang, M Siddiqi, Y Freund, C Leslie Journal of bioinformatics and computational biology 3 (03), 527-550, 2005 | 257 | 2005 |
A cooperative microRNA-tumor suppressor gene network in acute T-cell lymphoblastic leukemia (T-ALL) KJ Mavrakis, J Van Der Meulen, AL Wolfe, X Liu, E Mets, T Taghon, ... Nature genetics 43 (7), 673, 2011 | 245 | 2011 |
Ubiquitously transcribed genes use alternative polyadenylation to achieve tissue-specific expression S Lianoglou, V Garg, JL Yang, CS Leslie, C Mayr Genes & development 27 (21), 2380-2396, 2013 | 238 | 2013 |
Fast string kernels using inexact matching for protein sequences C Leslie, R Kuang Journal of Machine Learning Research 5 (Nov), 1435-1455, 2004 | 193 | 2004 |
Ibrutinib resistance in chronic lymphocytic leukemia RR Furman, S Cheng, P Lu, M Setty, AR Perez, A Guo, J Racchumi, G Xu, ... The New England journal of medicine 370 (24), 2352, 2014 | 191 | 2014 |
Sequence and chromatin determinants of cell-type–specific transcription factor binding A Arvey, P Agius, WS Noble, C Leslie Genome research 22 (9), 1723-1734, 2012 | 181 | 2012 |