Kevin Docherty
Kevin Docherty
Professor of Biochemistry, University of Aberdeen
Verified email at abdn.ac.uk - Homepage
TitleCited byYear
Post-translational proteolysis in polypeptide hormone biosynthesis
K Docherty, DF Steiner
Annual Review of Physiology 44 (1), 625-638, 1982
6441982
Pancreatic duodenal homeobox–1, PDX-1, a major regulator of beta cell identity and function
CM McKinnon, K Docherty
Diabetologia 44 (10), 1203-1214, 2001
2922001
Missense mutations in the insulin promoter factor-1 gene predispose to type 2 diabetes
WM Macfarlane, TM Frayling, S Ellard, JC Evans, LIS Allen, MP Bulman, ...
The Journal of clinical investigation 104 (9), R33-R39, 1999
2731999
Glucose stimulates translocation of the homeodomain transcription factor PDX1 from the cytoplasm to the nucleus in pancreatic β-cells
WM Macfarlane, CM McKinnon, ZA Felton-Edkins, H Cragg, RFL James, ...
Journal of Biological Chemistry 274 (2), 1011-1016, 1999
2461999
The insulin gene promoter: a simplified nomenclature
M German, S Ashcroft, K Docherty, H Edlund, T Edlund, S Goodison, ...
Diabetes 44 (8), 1002-1004, 1995
2171995
The p38/reactivating kinase mitogen-activated protein kinase cascade mediates the activation of the transcription factor insulin upstream factor 1 and insulin gene …
WM Macfarlane, SB Smith, RFL James, AD Clifton, YN Doza, P Cohen, ...
Journal of Biological Chemistry 272 (33), 20936-20944, 1997
2051997
Positive and negative regulation of the human insulin gene by multiple trans-acting factors.
DS Boam, AR Clark, K Docherty
Journal of Biological Chemistry 265 (14), 8285-8296, 1990
1761990
Comparative analysis of insulin gene promoters: implications for diabetes research
CW Hay, K Docherty
Diabetes 55 (12), 3201-3213, 2006
1752006
Pancreatic transcription factors and their role in the birth, life and survival of the pancreatic β cell
AS Bernardo, CW Hay, K Docherty
Molecular and cellular endocrinology 294 (1-2), 1-9, 2008
1712008
Nutrient regulation of insulin gene expression.
K Docherty, AR Clark
The FASEB journal 8 (1), 20-27, 1994
1631994
Glucose modulates the binding activity of the β-cell transcription factor IUF1 in a phosphorylation-dependent manner
WM MacFarlane, ML Read, M Gilligan, I Bujalska, K Docherty
Biochemical Journal 303 (2), 625-631, 1994
1611994
Conversion of proinsulin to insulin: involvement of a 31,500 molecular weight thiol protease
K Docherty, RJ Carroll, DF Steiner
Proceedings of the National Academy of Sciences 79 (15), 4613-4617, 1982
1481982
A member of the eukaryotic subtilisin family (PC3) has the enzymic properties of the type 1 proinsulin-converting endopeptidase
EM Bailyes, KIJ Shennan, AJ Seal, SP Smeekens, DF Steiner, JC Hutton, ...
Biochemical Journal 285 (2), 391-394, 1992
1401992
Golgi/granule processing of peptide hormone and neuropeptide precursors: a minireview
DF Steiner, K Docherty, R Carroll
Journal of cellular biochemistry 24 (2), 121-130, 1984
1381984
Phosphorylation-dependent nucleocytoplasmic shuttling of pancreatic duodenal homeobox-1
LJ Elrick, K Docherty
Diabetes 50 (10), 2244-2252, 2001
1362001
C/EBPβ reprograms white 3T3-L1 preadipocytes to a brown adipocyte pattern of gene expression
G Karamanlidis, A Karamitri, K Docherty, DG Hazlerigg, MA Lomax
Journal of Biological Chemistry 282 (34), 24660-24669, 2007
1132007
Insulin stimulates pancreatic–duodenal homoeobox factor-1 (PDX1) DNA-binding activity and insulin promoter activity in pancreatic β cells
H WU, WM MACFARLANE, M TADAYYON, JRS ARCH, RFL JAMES, ...
Biochemical Journal 344 (3), 813-818, 1999
1021999
The human insulin gene linked polymorphic region exhibits an altered DNA structure
MCU Hammond-Kosack, B Dobrinski, R Lurz, K Docherty, MW Kilpatrick
Nucleic acids research 20 (2), 231-236, 1992
1011992
Relative contribution of PDX-1, MafA and E47/β2 to the regulation of the human insulin promoter
HM Docherty, CW Hay, LA Ferguson, J Barrow, E Durward, K Docherty
Biochemical Journal 389 (3), 813-820, 2005
982005
Negative regulation of transcription in eukaryotes.
AR Clark, K Docherty
Biochemical journal 296 (Pt 3), 521, 1993
971993
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