| Transient formation of water-conducting states in membrane transporters J Li, SA Shaikh, G Enkavi, PC Wen, Z Huang, E Tajkhorshid Proceedings of the National Academy of Sciences 110 (19), 7696-7701, 2013 | 105 | 2013 |
| Shifts in the selectivity filter dynamics cause modal gating in K+ channels S Jekhmane, J Medeiros-Silva, J Li, F Kümmerer, C Müller-Hermes, ... Nature communications 10 (1), 123, 2019 | 75 | 2019 |
| Rapid constriction of the selectivity filter underlies C-type inactivation in the KcsA potassium channel J Li, J Ostmeyer, LG Cuello, E Perozo, B Roux Journal of General Physiology 150 (10), 1408-1420, 2018 | 73 | 2018 |
| Ion-releasing state of a secondary membrane transporter J Li, E Tajkhorshid Biophysical Journal 97 (11), L29-L31, 2009 | 66 | 2009 |
| Further optimization and validation of the classical drude polarizable protein force field FY Lin, J Huang, P Pandey, C Rupakheti, J Li, B Roux, AD MacKerell Jr Journal of chemical theory and computation 16 (5), 3221-3239, 2020 | 62 | 2020 |
| Visualizing functional motions of membrane transporters with molecular dynamics simulations SA Shaikh, J Li, G Enkavi, PC Wen, Z Huang, E Tajkhorshid Biochemistry 52 (4), 569-587, 2013 | 57 | 2013 |
| Computational characterization of structural dynamics underlying function in active membrane transporters J Li, PC Wen, M Moradi, E Tajkhorshid Current opinion in structural biology 31, 96-105, 2015 | 55 | 2015 |
| Mechanism of C-type inactivation in the hERG potassium channel J Li, R Shen, B Reddy, E Perozo, B Roux Science Advances 7 (5), eabd6203, 2021 | 39 | 2021 |
| Structural determinants of the mechanical stability of α-catenin J Li, J Newhall, N Ishiyama, C Gottardi, M Ikura, DE Leckband, ... Journal of Biological Chemistry 290 (31), 18890-18903, 2015 | 37 | 2015 |
| Chemical substitutions in the selectivity filter of potassium channels do not rule out constricted-like conformations for C-type inactivation J Li, J Ostmeyer, E Boulanger, H Rui, E Perozo, B Roux Proceedings of the National Academy of Sciences 114 (42), 11145-11150, 2017 | 31 | 2017 |
| A gate-free pathway for substrate release from the inward-facing state of the Na+-galactose transporter J Li, E Tajkhorshid Biochimica et Biophysica Acta (BBA)-Biomembranes 1818 (2), 263-271, 2012 | 27 | 2012 |
| Calcineurin regulatory subunit B is a unique calcium sensor that regulates calcineurin in both calcium‐dependent and calcium‐independent manner J Li, ZG Jia, WC Zhou, Q Wei Proteins: Structure, Function, and Bioinformatics 77 (3), 612-623, 2009 | 24 | 2009 |
| Binding partner-and force-promoted changes in αE-catenin conformation probed by native cysteine labeling K Terekhova, S Pokutta, YS Kee, J Li, E Tajkhorshid, G Fuller, AR Dunn, ... Scientific Reports 9 (1), 15375, 2019 | 23 | 2019 |
| Salt bridges gate α-catenin activation at intercellular junctions S Barrick, J Li, X Kong, A Ray, E Tajkhorshid, D Leckband Molecular biology of the cell 29 (2), 111-122, 2018 | 21 | 2018 |
| Atomic mutagenesis in ion channels with engineered stoichiometry JD Lueck, AL Mackey, DT Infield, JD Galpin, J Li, B Roux, CA Ahern Elife 5, e18976, 2016 | 21 | 2016 |
| Computational study of non-conductive selectivity filter conformations and C-type inactivation in a voltage-dependent potassium channel J Li, R Shen, A Rohaim, R Mendoza Uriarte, M Fajer, E Perozo, B Roux Journal of General Physiology 153 (9), e202112875, 2021 | 15 | 2021 |
| Open and closed structures of a barium-blocked potassium channel A Rohaim, LD Gong, J Li, H Rui, L Blachowicz, B Roux Journal of molecular biology 432 (17), 4783-4798, 2020 | 15 | 2020 |
| Peptides derived from transcription factor EB bind to calcineurin at a similar region as the NFAT-type motif R Song, J Li, J Zhang, L Wang, L Tong, P Wang, H Yang, Q Wei, H Cai, ... Biochimie 142, 158-167, 2017 | 15 | 2017 |
| A distinct mechanism of C-type inactivation in the Kv-like KcsA mutant E71V A Rohaim, BJA Vermeulen, J Li, F Kümmerer, F Napoli, L Blachowicz, ... Nature Communications 13 (1), 1574, 2022 | 14 | 2022 |
| A novel peptide exerts potent immunosuppression by blocking the two-site interaction of NFAT with calcineurin L Wang, N Cheng, P Wang, J Li, A Jia, W Li, N Zhang, Y Yin, L Tong, ... Journal of Biological Chemistry 295 (9), 2760-2770, 2020 | 12 | 2020 |
Emad Tajkhorshid, PhDProfessor of Biochemistry and Biophysics, University of IllinoisVerified email at illinois.edu
