Neekesh V. Dharia
Neekesh V. Dharia
Clinical Instructor and Postdoctoral Fellow at Dana-Farber Cancer Institute, Boston Children's
Verified email at dfci.harvard.edu - Homepage
Title
Cited by
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Year
Spiroindolones, a potent compound class for the treatment of malaria
M Rottmann, C McNamara, BKS Yeung, MCS Lee, B Zou, B Russell, ...
science 329 (5996), 1175-1180, 2010
9392010
Computational correction of copy number effect improves specificity of CRISPR–Cas9 essentiality screens in cancer cells
RM Meyers, JG Bryan, JM McFarland, BA Weir, AE Sizemore, H Xu, ...
Nature genetics 49 (12), 1779-1784, 2017
4692017
Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery
S Meister, DM Plouffe, KL Kuhen, GMC Bonamy, T Wu, SW Barnes, ...
Science 334 (6061), 1372-1377, 2011
2822011
Mitotic evolution of Plasmodium falciparum shows a stable core genome but recombination in antigen families
SER Bopp, MJ Manary, AT Bright, GL Johnston, NV Dharia, FL Luna, ...
PLoS Genet 9 (2), e1003293, 2013
1662013
Use of high-density tiling microarrays to identify mutations globally and elucidate mechanisms of drug resistance in Plasmodium falciparum
NV Dharia, ABS Sidhu, MB Cassera, SJ Westenberger, SER Bopp, ...
Genome biology 10 (2), R21, 2009
1542009
Piperaquine resistance is associated with a copy number variation on chromosome 5 in drug-pressured Plasmodium falciparum parasites
RT Eastman, NV Dharia, EA Winzeler, DA Fidock
Antimicrobial agents and chemotherapy 55 (8), 3908-3916, 2011
1262011
Validation of isoleucine utilization targets in Plasmodium falciparum
ES Istvan, NV Dharia, SE Bopp, I Gluzman, EA Winzeler, DE Goldberg
Proceedings of the National Academy of Sciences 108 (4), 1627-1632, 2011
1102011
Whole-genome sequencing and microarray analysis of ex vivo Plasmodium vivax reveal selective pressure on putative drug resistance genes
NV Dharia, AT Bright, SJ Westenberger, SW Barnes, S Batalov, K Kuhen, ...
Proceedings of the National Academy of Sciences 107 (46), 20045-20050, 2010
1082010
A systems-based analysis of Plasmodium vivax lifecycle transcription from human to mosquito
SJ Westenberger, CM McClean, R Chattopadhyay, NV Dharia, JM Carlton, ...
PLoS Negl Trop Dis 4 (4), e653, 2010
1012010
Genome-wide nucleosome mapping of Plasmodium falciparum reveals histone-rich coding and histone-poor intergenic regions and chromatin remodeling of core …
SJ Westenberger, L Cui, N Dharia, E Winzeler, L Cui
BMC genomics 10 (1), 610, 2009
802009
A Chemical Genomic Analysis of Decoquinate, a Plasmodium falciparum Cytochrome b Inhibitor
T Nam, CW McNamara, S Bopp, NV Dharia, S Meister, GMC Bonamy, ...
ACS chemical biology 6 (11), 1214-1222, 2011
762011
Genome scanning of Amazonian Plasmodium falciparum shows subtelomeric instability and clindamycin-resistant parasites
NV Dharia, D Plouffe, SER Bopp, GE González-Páez, C Lucas, C Salas, ...
Genome research 20 (11), 1534-1544, 2010
662010
CRISPR-Cas9 screen reveals a MYCN-amplified neuroblastoma dependency on EZH2
L Chen, G Alexe, NV Dharia, L Ross, AB Iniguez, AS Conway, EJ Wang, ...
The Journal of clinical investigation 128 (1), 446-462, 2018
552018
EWS/FLI confers tumor cell synthetic lethality to CDK12 inhibition in Ewing sarcoma
AB Iniguez, B Stolte, EJ Wang, AS Conway, G Alexe, NV Dharia, ...
Cancer cell 33 (2), 202-216. e6, 2018
512018
Selective gene dependencies in MYCN-amplified neuroblastoma include the core transcriptional regulatory circuitry
AD Durbin, MW Zimmerman, NV Dharia, BJ Abraham, AB Iniguez, ...
Nature genetics 50 (9), 1240-1246, 2018
492018
Targetable vulnerabilities in T-and NK-cell lymphomas identified through preclinical models
SY Ng, N Yoshida, AL Christie, M Ghandi, NV Dharia, J Dempster, ...
Nature communications 9 (1), 1-11, 2018
372018
Genome-scale CRISPR-Cas9 screen identifies druggable dependencies in TP53 wild-type Ewing sarcoma
B Stolte, AB Iniguez, NV Dharia, AL Robichaud, AS Conway, AM Morgan, ...
Journal of Experimental Medicine 215 (8), 2137-2155, 2018
242018
A combination CDK4/6 and IGF1R inhibitor strategy for Ewing sarcoma
LM Guenther, NV Dharia, L Ross, A Conway, AL Robichaud, JL Catlett, ...
Clinical Cancer Research 25 (4), 1343-1357, 2019
212019
Genomics and systems biology in malaria drug discovery.
NV Dharia, A Chatterjee, EA Winzeler
Current opinion in investigational drugs (London, England: 2000) 11 (2), 131-138, 2010
192010
Comparative proteomics reveals a diagnostic signature for pulmonary head‐and‐neck cancer metastasis
H Bohnenberger, L Kaderali, P Ströbel, D Yepes, U Plessmann, ...
EMBO molecular medicine 10 (9), e8428, 2018
172018
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