Craig S. Atwood, Ph.D.
Craig S. Atwood, Ph.D.
Associate Professor of Medicine, University of Wisconsin-Madison
Verified email at - Homepage
Cited by
Cited by
Oxidative damage is the earliest event in Alzheimer disease
A Nunomura, G Perry, G Aliev, K Hirai, A Takeda, EK Balraj, PK Jones, ...
Journal of Neuropathology & Experimental Neurology 60 (8), 759-767, 2001
Treatment with a copper-zinc chelator markedly and rapidly inhibits β-amyloid accumulation in Alzheimer's disease transgenic mice
RA Cherny, CS Atwood, ME Xilinas, DN Gray, WD Jones, CA McLean, ...
Neuron 30 (3), 665-676, 2001
Mitochondrial abnormalities in Alzheimer's disease
K Hirai, G Aliev, A Nunomura, H Fujioka, RL Russell, CS Atwood, ...
Journal of Neuroscience 21 (9), 3017-3023, 2001
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ...
Nature genetics 51 (3), 414-430, 2019
The Aβ peptide of Alzheimer's disease directly produces hydrogen peroxide through metal ion reduction
X Huang, CS Atwood, MA Hartshorn, G Multhaup, LE Goldstein, ...
Biochemistry 38 (24), 7609-7616, 1999
Dramatic aggregation of Alzheimer Aβ by Cu (II) is induced by conditions representing physiological acidosis
CS Atwood, RD Moir, X Huang, RC Scarpa, NME Bacarra, DM Romano, ...
Journal of Biological Chemistry 273 (21), 12817-12826, 1998
Cu (II) potentiation of Alzheimer Aβ neurotoxicity: correlation with cell-free hydrogen peroxide production and metal reduction
X Huang, MP Cuajungco, CS Atwood, MA Hartshorn, JDA Tyndall, ...
Journal of Biological Chemistry 274 (52), 37111-37116, 1999
Characterization of Copper Interactions with Alzheimer Amyloid β Peptides: Identification of an Attomolar‐Affinity Copper Binding Site on Amyloid β1‐42
CS Atwood, RC Scarpa, X Huang, RD Moir, WD Jones, DP Fairlie, ...
Journal of neurochemistry 75 (3), 1219-1233, 2000
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease
R Sims, SJ Van Der Lee, AC Naj, C Bellenguez, N Badarinarayan, ...
Nature genetics 49 (9), 1373-1384, 2017
Metal binding and oxidation of amyloid-β within isolated senile plaque cores: Raman microscopic evidence
J Dong, CS Atwood, VE Anderson, SL Siedlak, MA Smith, G Perry, ...
Biochemistry 42 (10), 2768-2773, 2003
Aqueous dissolution of Alzheimer's disease Aβ amyloid deposits by biometal depletion
RA Cherny, JT Legg, CA McLean, DP Fairlie, X Huang, CS Atwood, ...
Journal of Biological Chemistry 274 (33), 23223-23228, 1999
Evidence that the β-amyloid plaques of Alzheimer's disease represent the redox-silencing and entombment of Aβ by zinc
MP Cuajungco, LE Goldstein, A Nunomura, MA Smith, JT Lim, CS Atwood, ...
Journal of Biological Chemistry 275 (26), 19439-19442, 2000
Redox-active iron mediates amyloid-β toxicity
CA Rottkamp, AK Raina, X Zhu, E Gaier, AI Bush, CS Atwood, M Chevion, ...
Free Radical Biology and Medicine 30 (4), 447-450, 2001
Copper mediates dityrosine cross-linking of Alzheimer's amyloid-β
CS Atwood, G Perry, H Zeng, Y Kato, WD Jones, KQ Ling, X Huang, ...
Biochemistry 43 (2), 560-568, 2004
Zinc-induced Alzheimer's Aβ1–40 aggregation is mediated by conformational factors
X Huang, CS Atwood, RD Moir, MA Hartshorn, JP Vonsattel, RE Tanzi, ...
Journal of Biological Chemistry 272 (42), 26464-26470, 1997
Effects of hormone therapy on cognition and mood in recently postmenopausal women: findings from the randomized, controlled KEEPS–cognitive and affective study
CE Gleason, NM Dowling, W Wharton, JAE Manson, VM Miller, ...
PLoS medicine 12 (6), e1001833, 2015
Amyloid-β: a chameleon walking in two worlds: a review of the trophic and toxic properties of amyloid-β
CS Atwood, ME Obrenovich, T Liu, H Chan, G Perry, MA Smith, ...
Brain Research Reviews 43 (1), 1-16, 2003
Is oxidative damage the fundamental pathogenic mechanism of Alzheimer’s and other neurodegenerative diseases?
G Perry, A Nunomura, K Hirai, X Zhu, M Prez, J Avila, RJ Castellani, ...
Free Radical Biology and Medicine 33 (11), 1475-1479, 2002
Differential activation of neuronal ERK, JNK/SAPK and p38 in Alzheimer disease: the ‘two hit’hypothesis
X Zhu, RJ Castellani, A Takeda, A Nunomura, CS Atwood, G Perry, ...
Mechanisms of ageing and development 123 (1), 39-46, 2001
Most reported genetic associations with general intelligence are probably false positives
CF Chabris, BM Hebert, DJ Benjamin, J Beauchamp, D Cesarini, ...
Psychological science 23 (11), 1314-1323, 2012
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