| Olive-oil-derived oleocanthal enhances β-amyloid clearance as a potential neuroprotective mechanism against Alzheimer’s disease: In vitro and in vivo studies AH Abuznait, H Qosa, BA Busnena, KA El Sayed, A Kaddoumi ACS chemical neuroscience 4 (6), 973-982, 2013 | 296 | 2013 |
| Enhanced brain amyloid-β clearance by rifampicin and caffeine as a possible protective mechanism against Alzheimer's disease H Qosa, AH Abuznait, RA Hill, A Kaddoumi Journal of Alzheimer's Disease 31 (1), 151-165, 2012 | 194 | 2012 |
| Paclitaxel loaded PEG5000–DSPE micelles as pulmonary delivery platform: formulation characterization, tissue distribution, plasma pharmacokinetics, and toxicological evaluation KK Gill, S Nazzal, A Kaddoumi European Journal of Pharmaceutics and Biopharmaceutics 79 (2), 276-284, 2011 | 193 | 2011 |
| Role of ABC transporters in the pathogenesis of Alzheimer’s disease AH Abuznait, A Kaddoumi ACS chemical neuroscience 3 (11), 820-831, 2012 | 155 | 2012 |
| Oleocanthal enhances amyloid-β clearance from the brains of TgSwDI mice and in vitro across a human blood-brain barrier model H Qosa, YS Batarseh, MM Mohyeldin, KA El Sayed, JN Keller, ... ACS chemical neuroscience 6 (11), 1849-1859, 2015 | 151 | 2015 |
| Differences in amyloid-β clearance across mouse and human blood–brain barrier models: kinetic analysis and mechanistic modeling H Qosa, BS Abuasal, IA Romero, B Weksler, PO Couraud, JN Keller, ... Neuropharmacology 79, 668-678, 2014 | 146 | 2014 |
| Profiling gene expression in human placentae of different gestational ages: an OPRU Network and UW SCOR Study AM Mikheev, T Nabekura, A Kaddoumi, TK Bammler, R Govindarajan, ... Reproductive sciences 15 (9), 866-877, 2008 | 140 | 2008 |
| Nilotinib potentiates anticancer drug sensitivity in murine ABCB1-, ABCG2-, and ABCC10-multidrug resistance xenograft models AK Tiwari, K Sodani, C Dai, AH Abuznait, S Singh, ZJ Xiao, A Patel, ... Cancer letters 328 (2), 307-317, 2013 | 126 | 2013 |
| Mixed micelles of PEG2000-DSPE and vitamin-E TPGS for concurrent delivery of paclitaxel and parthenolide: enhanced chemosenstization and antitumor efficacy against non-small … KK Gill, A Kaddoumi, S Nazzal European journal of pharmaceutical sciences 46 (1-2), 64-71, 2012 | 122 | 2012 |
| PEG–lipid micelles as drug carriers: physiochemical attributes, formulation principles and biological implication KK Gill, A Kaddoumi, S Nazzal Journal of drug targeting 23 (3), 222-231, 2015 | 99 | 2015 |
| Extra-virgin olive oil attenuates amyloid-β and tau pathologies in the brains of TgSwDI mice H Qosa, LA Mohamed, YS Batarseh, S Alqahtani, B Ibrahim, H LeVine III, ... The Journal of Nutritional Biochemistry 26 (12), 1479-1490, 2015 | 97 | 2015 |
| Up-regulation of P-glycoprotein reduces intracellular accumulation of beta amyloid: investigation of P-glycoprotein as a novel therapeutic target for Alzheimer's disease AH Abuznait, C Cain, D Ingram, D Burk, A Kaddoumi Journal of Pharmacy and Pharmacology 63 (8), 1111-1118, 2011 | 96 | 2011 |
| Experimental models for predicting drug absorption and metabolism S Alqahtani, LA Mohamed, A Kaddoumi Expert Opinion on Drug Metabolism & Toxicology 9 (10), 1241-1254, 2013 | 92 | 2013 |
| Enhancement of intestinal permeability utilizing solid lipid nanoparticles increases γ-tocotrienol oral bioavailability BS Abuasal, C Lucas, B Peyton, A Alayoubi, S Nazzal, PW Sylvester, ... Lipids 47, 461-469, 2012 | 89 | 2012 |
| Alborixin clears amyloid-β by inducing autophagy through PTEN-mediated inhibition of the AKT pathway A Wani, M Gupta, M Ahmad, AM Shah, AU Ahsan, PH Qazi, F Malik, ... Autophagy 15 (10), 1810-1828, 2019 | 88 | 2019 |
| Cellular uptake, antioxidant and antiproliferative activity of entrapped α-tocopherol and γ-tocotrienol in poly (lactic-co-glycolic) acid (PLGA) and chitosan covered PLGA … S Alqahtani, L Simon, CE Astete, A Alayoubi, PW Sylvester, S Nazzal, ... Journal of colloid and interface science 445, 243-251, 2015 | 84 | 2015 |
| Amyloid-β and astrocytes interplay in amyloid-β related disorders YS Batarseh, QV Duong, YM Mousa, SB Al Rihani, K Elfakhri, ... International journal of molecular sciences 17 (3), 338, 2016 | 83 | 2016 |
| Discovery of novel GSK-3β inhibitors with potent in vitro and in vivo activities and excellent brain permeability using combined ligand-and structure-based virtual screening MA Khanfar, RA Hill, A Kaddoumi, KA El Sayed Journal of medicinal chemistry 53 (24), 8534-8545, 2010 | 81 | 2010 |
| Crocus sativus Extract Tightens the Blood-Brain Barrier, Reduces Amyloid β Load and Related Toxicity in 5XFAD Mice YS Batarseh, SS Bharate, V Kumar, A Kumar, RA Vishwakarma, ... ACS chemical neuroscience 8 (8), 1756-1766, 2017 | 78 | 2017 |
| Overcoming poor aqueous solubility of drugs for oral delivery T Heimbach, D Fleisher, A Kaddoumi Prodrugs: Challenges and Rewards Part 1, 157-215, 2007 | 77 | 2007 |
