Doug Speed
Doug Speed
Aarhus University and University College London
Verified email at - Homepage
TitleCited byYear
The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups
C Curtis, SP Shah, SF Chin, G Turashvili, OM Rueda, MJ Dunning, ...
Nature 486 (7403), 346-352, 2012
Improved heritability estimation from genome-wide SNPs
D Speed, G Hemani, MR Johnson, DJ Balding
The American Journal of Human Genetics 91 (6), 1011-1021, 2012
Reevaluation of SNP heritability in complex human traits
D Speed, N Cai, MR Johnson, S Nejentsev, DJ Balding, ...
Nature genetics 49 (7), 986, 2017
MultiBLUP: improved SNP-based prediction for complex traits
D Speed, DJ Balding
Genome research 24 (9), 1550-1557, 2014
Relatedness in the post-genomic era: is it still useful?
D Speed, DJ Balding
Nature Reviews Genetics 16 (1), 33-44, 2015
The genomic and phenotypic diversity of Schizosaccharomyces pombe
DC Jeffares, C Rallis, A Rieux, D Speed, M Převorovský, T Mourier, ...
Nature genetics 47 (3), 235-241, 2015
Systems genetics identifies Sestrin 3 as a regulator of a proconvulsant gene network in human epileptic hippocampus
MR Johnson, J Behmoaras, L Bottolo, ML Krishnan, K Pernhorst, ...
Nature communications 6 (1), 1-11, 2015
Transient structural variations have strong effects on quantitative traits and reproductive isolation in fission yeast
DC Jeffares, C Jolly, M Hoti, D Speed, L Shaw, C Rallis, F Balloux, ...
Nature communications 8 (1), 1-11, 2017
Systems genetics identifies a convergent gene network for cognition and neurodevelopmental disease
MR Johnson, K Shkura, SR Langley, A Delahaye-Duriez, P Srivastava, ...
Nature neuroscience 19 (2), 223, 2016
Describing the genetic architecture of epilepsy through heritability analysis
D Speed, TJ O’Brien, A Palotie, K Shkura, AG Marson, DJ Balding, ...
Brain 137 (10), 2680-2689, 2014
Genetic determinants of common epilepsies: a meta-analysis of genome-wide association studies
TILAE Consortium
The Lancet. Neurology 13 (9), 893, 2014
A genome-wide association study and biological pathway analysis of epilepsy prognosis in a prospective cohort of newly treated epilepsy
D Speed, C Hoggart, S Petrovski, I Tachmazidou, A Coffey, A Jorgensen, ...
Human molecular genetics 23 (1), 247-258, 2014
Genome-wide analysis of blood pressure variability and ischemic stroke
S Yadav, I Cotlarciuc, PB Munroe, MS Khan, MA Nalls, S Bevan, ...
Stroke 44 (10), 2703-2709, 2013
SumHer better estimates the SNP heritability of complex traits from summary statistics
D Speed, DJ Balding
Nature genetics 51 (2), 277-284, 2019
Genetic complexity of Crohn’s disease in two large Ashkenazi Jewish families
AP Levine, N Pontikos, ER Schiff, L Jostins, D Speed, LB Lovat, JC Barrett, ...
Gastroenterology 151 (4), 698-709, 2016
Genetic correlations among psychiatric and immune‐related phenotypes based on genome‐wide association data
DS Tylee, J Sun, JL Hess, MA Tahir, E Sharma, R Malik, BB Worrall, ...
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 177 …, 2018
Response to Lee et al.: SNP-based heritability analysis with dense data
D Speed, G Hemani, MR Johnson, DJ Balding
Am. J. Hum. Genet 5, 1155-1157, 2013
Genetic variation in CFH predicts phenytoin-induced maculopapular exanthema in European-descent patients
M McCormack, H Gui, A Ingason, D Speed, GEB Wright, EJ Zhang, ...
Neurology 90 (4), e332-e341, 2018
Mendelian randomization study shows no causal relationship between circulating urate levels and Parkinson's disease
DA Kia, AJ Noyce, J White, D Speed, A Nicolas, IPDGC collaborators, ...
Annals of neurology 84 (2), 191-199, 2018
Better estimation of SNP heritability from summary statistics provides a new understanding of the genetic architecture of complex traits
D Speed, D Balding
bioRxiv, 284976, 2018
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