A draft genome of Yersinia pestis from victims of the Black Death KI Bos, VJ Schuenemann, GB Golding, HA Burbano, N Waglechner, ... Nature 478 (7370), 506-510, 2011 | 629 | 2011 |
Combinations of antibiotics and nonantibiotic drugs enhance antimicrobial efficacy L Ejim, MA Farha, SB Falconer, J Wildenhain, BK Coombes, M Tyers, ... Nature Chemical Biology 7 (6), 348-350, 2011 | 386 | 2011 |
Aspergillomarasmine A overcomes metallo-β-lactamase antibiotic resistance AM King, SA Reid-Yu, W Wang, DT King, G De Pascale, NC Strynadka, ... Nature 510 (7506), 503-506, 2014 | 374 | 2014 |
Targeted enrichment of ancient pathogens yielding the pPCP1 plasmid of Yersinia pestis from victims of the Black Death VJ Schuenemann, K Bos, S DeWitte, S Schmedes, J Jamieson, A Mittnik, ... Proceedings of the National Academy of Sciences 108 (38), E746-E752, 2011 | 241 | 2011 |
Molecular analysis as an aid to assess the public health risk of non-O157 Shiga toxin-producing Escherichia coli strains BK Coombes, ME Wickham, M Mascarenhas, S Gruenheid, BB Finlay, ... Applied Environmental Microbiology 74 (7), 2153-2160, 2008 | 220 | 2008 |
Analysis of the contribution of Salmonella pathogenicity islands 1 and 2 to enteric disease progression using a novel bovine ileal loop model and a murine model of infectious … BK Coombes, BA Coburn, AA Potter, S Gomis, K Mirakhur, Y Li, BB Finlay Infection and Immunity 73 (11), 7161-7169, 2005 | 189 | 2005 |
Expression and secretion of Salmonella pathogenicity island-2 virulence genes in response to acidification exhibit differential requirements of a functional type III secretion … BK Coombes, NF Brown, Y Valdez, JH Brumell, BB Finlay Journal of Biological Chemistry 279 (48), 49804-49815, 2004 | 183 | 2004 |
Genome sequence of adherent-invasive Escherichia coli and comparative genomic analysis with other E. coli pathotypes JHE Nash, A Villegas, AM Kropinski, R Aguilar-Valenzuela, P Konczy, ... BMC Genomics 11 (1), 667, 2010 | 147 | 2010 |
Salmonella pathogenicity island 2 is expressed prior to penetrating the intestine NF Brown, BA Vallance, BK Coombes, Y Valdez, BA Coburn, BB Finlay PLoS Pathogens 1 (3), e32, 2005 | 145 | 2005 |
Identification of MEK‐and phosphoinositide 3‐kinase‐dependent signalling as essential events during Chlamydia pneumoniae invasion of HEp2 cells BK Coombes, JB Mahony Cellular Microbiology 4 (7), 447-460, 2002 | 144 | 2002 |
Chlamydia pneumoniae infection of human endothelial cells induces proliferation of smooth muscle cells via an endothelial cell-derived soluble factor (s) BK Coombes, JB Mahony Infection and Immunity 67 (6), 2909-2915, 1999 | 133 | 1999 |
Pentamidine sensitizes Gram-negative pathogens to antibiotics and overcomes acquired colistin resistance JM Stokes, CR MacNair, B Ilyas, S French, JP Côté, C Bouwman, ... Nature microbiology 2 (5), 1-8, 2017 | 130 | 2017 |
Bacterial genetic determinants of non-O157 STEC outbreaks and hemolytic-uremic syndrome after infection ME Wickham, C Lupp, M Mascarenhas, A Vázquez, BK Coombes, ... The Journal of Infectious Diseases 194 (6), 819-827, 2006 | 130 | 2006 |
Crossing the line: selection and evolution of virulence traits NF Brown, ME Wickham, BK Coombes, BB Finlay PLoS Pathogens 2 (5), e42, 2006 | 123 | 2006 |
Negative regulation of Salmonella pathogenicity island 2 is required for contextual control of virulence during typhoid BK Coombes, ME Wickham, MJ Lowden, NF Brown, BB Finlay Proceedings of the National Academy of Sciences 102 (48), 17460-17465, 2005 | 121 | 2005 |
cDNA array analysis of altered gene expression in human endothelial cells in response to Chlamydia pneumoniae infection BK Coombes, JB Mahony Infection and Immunity 69 (3), 1420-1427, 2001 | 115 | 2001 |
FimH adhesin of type 1 fimbriae is a potent inducer of innate antimicrobial responses which requires TLR4 and type 1 interferon signalling AA Ashkar, KL Mossman, BK Coombes, CL Gyles, R Mackenzie PLoS Pathogens 4 (12), e1000233, 2008 | 113 | 2008 |
Persistent infection with Crohn’s disease-associated adherent-invasive Escherichia coli leads to chronic inflammation and intestinal fibrosis CLN Small, SA Reid-Yu, JB McPhee, BK Coombes Nature communications 4 (1), 1-12, 2013 | 102 | 2013 |
Overcoming mcr-1 mediated colistin resistance with colistin in combination with other antibiotics CR MacNair, JM Stokes, LA Carfrae, AA Fiebig-Comyn, BK Coombes, ... Nature communications 9 (1), 1-8, 2018 | 100 | 2018 |
NleG Type 3 effectors from enterohaemorrhagic Escherichia coli are U-Box E3 ubiquitin ligases B Wu, T Skarina, A Yee, MC Jobin, R DiLeo, A Semesi, C Fares, A Lemak, ... PLoS Pathog 6 (6), e1000960, 2010 | 94 | 2010 |