Brian Coombes
Brian Coombes
McMaster University, Department of Biochemistry and Biomedical Sciences
Verified email at mcmaster.ca - Homepage
TitleCited byYear
A draft genome of Yersinia pestis from victims of the Black Death
KI Bos, VJ Schuenemann, GB Golding, HA Burbano, N Waglechner, ...
Nature 478 (7370), 506, 2011
5062011
Combinations of antibiotics and nonantibiotic drugs enhance antimicrobial efficacy
L Ejim, MA Farha, SB Falconer, J Wildenhain, BK Coombes, M Tyers, ...
Nature Chemical Biology 7 (6), 348-350, 2011
2922011
Aspergillomarasmine A overcomes metallo-β-lactamase antibiotic resistance
AM King, SA Reid-Yu, W Wang, DT King, G De Pascale, NC Strynadka, ...
Nature 510 (7506), 503, 2014
2692014
Molecular analysis as an aid to assess the public health risk of non-O157 Shiga toxin-producing Escherichia coli strains
BK Coombes, ME Wickham, M Mascarenhas, S Gruenheid, BB Finlay, ...
Applied Environmental Microbiology 74 (7), 2153-2160, 2008
1962008
Targeted enrichment of ancient pathogens yielding the pPCP1 plasmid of Yersinia pestis from victims of the Black Death
VJ Schuenemann, K Bos, S DeWitte, S Schmedes, J Jamieson, A Mittnik, ...
Proceedings of the National Academy of Sciences 108 (38), E746-E752, 2011
1942011
Analysis of the contribution of Salmonella pathogenicity islands 1 and 2 to enteric disease progression using a novel bovine ileal loop model and a murine model of infectious …
BK Coombes, BA Coburn, AA Potter, S Gomis, K Mirakhur, Y Li, BB Finlay
Infection and Immunity 73 (11), 7161-7169, 2005
1782005
Expression and secretion of Salmonella pathogenicity island-2 virulence genes in response to acidification exhibit differential requirements of a functional type III secretion …
BK Coombes, NF Brown, Y Valdez, JH Brumell, BB Finlay
Journal of Biological Chemistry 279 (48), 49804-49815, 2004
1582004
Identification of MEK‐and phosphoinositide 3‐kinase‐dependent signalling as essential events during Chlamydia pneumoniae invasion of HEp2 cells
BK Coombes, JB Mahony
Cellular Microbiology 4 (7), 447-460, 2002
1372002
Salmonella pathogenicity island 2 is expressed prior to penetrating the intestine
NF Brown, BA Vallance, BK Coombes, Y Valdez, BA Coburn, BB Finlay
PLoS Pathogens 1 (3), e32, 2005
1332005
Chlamydia pneumoniae infection of human endothelial cells induces proliferation of smooth muscle cells via an endothelial cell-derived soluble factor (s)
BK Coombes, JB Mahony
Infection and Immunity 67 (6), 2909-2915, 1999
1271999
Bacterial genetic determinants of non-O157 STEC outbreaks and hemolytic-uremic syndrome after infection
ME Wickham, C Lupp, M Mascarenhas, A Vázquez, BK Coombes, ...
The Journal of Infectious Diseases 194 (6), 819-827, 2006
1232006
Crossing the line: selection and evolution of virulence traits
NF Brown, ME Wickham, BK Coombes, BB Finlay
PLoS Pathogens 2 (5), e42, 2006
1232006
Genome sequence of adherent-invasive Escherichia coli and comparative genomic analysis with other E. coli pathotypes
JHE Nash, A Villegas, AM Kropinski, R Aguilar-Valenzuela, P Konczy, ...
BMC Genomics 11 (1), 667, 2010
1142010
Negative regulation of Salmonella pathogenicity island 2 is required for contextual control of virulence during typhoid
BK Coombes, ME Wickham, MJ Lowden, NF Brown, BB Finlay
Proceedings of the National Academy of Sciences 102 (48), 17460-17465, 2005
1142005
cDNA array analysis of altered gene expression in human endothelial cells in response to Chlamydia pneumoniae infection
BK Coombes, JB Mahony
Infection and Immunity 69 (3), 1420-1427, 2001
1042001
FimH adhesin of type 1 fimbriae is a potent inducer of innate antimicrobial responses which requires TLR4 and type 1 interferon signalling
AA Ashkar, KL Mossman, BK Coombes, CL Gyles, R Mackenzie
PLoS Pathogens 4 (12), e1000233, 2008
1032008
Salmonella enterica serovar Senftenberg human clinical isolates lacking SPI-1
Q Hu, B Coburn, W Deng, Y Li, X Shi, Q Lan, B Wang, BK Coombes, ...
Journal of Clinical Microbiology 46 (4), 1330-1336, 2008
882008
Targeting bacterial secretion systems: benefits of disarmament in the microcosm
C Baron, B Coombes
Infectious Disorders-Drug Targets (Formerly Current Drug Targets-Infectious …, 2007
832007
NleG Type 3 effectors from enterohaemorrhagic Escherichia coli are U-Box E3 ubiquitin ligases
B Wu, T Skarina, A Yee, MC Jobin, R DiLeo, A Semesi, C Fares, A Lemak, ...
PLoS pathogens 6 (6), e1000960, 2010
812010
Persistent infection with Crohn’s disease-associated adherent-invasive Escherichia coli leads to chronic inflammation and intestinal fibrosis
CLN Small, SA Reid-Yu, JB McPhee, BK Coombes
Nature communications 4, 1957, 2013
792013
The system can't perform the operation now. Try again later.
Articles 1–20