Progenitor T-cell differentiation from hematopoietic stem cells using Delta-like-4 and VCAM-1 S Shukla, MA Langley, J Singh, JM Edgar, M Mohtashami, ... Nature Methods 14 (5), 531-538, 2017 | 135 | 2017 |
Biomaterial strategies for delivering stem cells as a treatment for spinal cord injury A Agbay, JM Edgar, M Robinson, T Styan, K Wilson, J Schroll, J Ko, ... Cells Tissues Organs 202 (1-2), 42-51, 2016 | 50 | 2016 |
Fibrin Hydrogels Induce Mixed Dorsal/Ventral Spinal Neuron Identities During Differentiation of Human Induced Pluripotent Stem Cells JM Edgar, M Robinson, SM Willerth Acta Biomaterialia, 2017 | 47 | 2017 |
Incorporation of retinoic acid releasing microspheres into pluripotent stem cell aggregates for inducing neuronal differentiation JC Gomez, JM Edgar, AM Agbay, E Bibault, A Montgomery, NK Mohtaram, ... Cellular and Molecular Bioengineering 8, 307-319, 2015 | 33 | 2015 |
DLL4 and VCAM1 enhance the emergence of T cell–competent hematopoietic progenitors from human pluripotent stem cells YS Michaels, JM Edgar, MC Major, EL Castle, C Zimmerman, T Yin, ... Science Advances 8 (34), eabn5522, 2022 | 32 | 2022 |
Multi-objective optimization reveals time-and dose-dependent inflammatory cytokine-mediated regulation of human stem cell derived T-cell development JM Edgar, YS Michaels, PW Zandstra NPJ Regenerative Medicine 7 (1), 11, 2022 | 17 | 2022 |
Sex-biased human thymic architecture guides T cell development through spatially defined niches LN Stankiewicz, K Salim, EA Flaschner, YX Wang, JM Edgar, LJ Durland, ... Developmental Cell, 2024 | 4 | 2024 |
Inflammatory Cytokines Regulate T-cell Development from Blood Progenitor Cells in a Stage and Dose-Specific Manner JM Edgar, PW Zandstra bioRxiv, 2021 | 2 | 2021 |
Time-and lineage-resolved transcriptional profiling uncovers gene expression programs and clonal relationships that underlie human T lineage specification YS Michaels, MC Major, B Bonham-Carter, J Zhang, T Heydari, JM Edgar, ... bioRxiv, 2023.10. 06.561277, 2023 | 1 | 2023 |
Tracking the gene expression programs and clonal relationships that underlie mast, myeloid, and T lineage specification from stem cells YS Michaels, MC Major, B Bonham-Carter, J Zhang, T Heydari, JM Edgar, ... Cell Systems, 2024 | | 2024 |
ENGINEERED, CLINICALLY-RELEVANT PRODUCTION OF HELPER (CD4+) T CELLS FROM PLURIPOTENT STEM CELLS RD Jones, K Salim, JM Edgar, LN Stankiewicz, L Durland, J Gillies, ... Cytotherapy 26 (6), S228, 2024 | | 2024 |
Tunable differentiation of human CD4+ and CD8+ T cells from pluripotent stem cells RD Jones, K Salim, LN Stankiewicz, JM Edgar, L Leon, JK Gillies, ... bioRxiv, 2024.10. 29.620998, 2024 | | 2024 |
Engineering the thymic niche for T-cell differentiation from stem cells JM Edgar University of British Columbia, 2023 | | 2023 |
MEDIA FORMULATIONS AND METHODS FOR PRODUCING PROGENITOR T CELLS PW Zandstra, JM Edgar US Patent App. 17/776,575, 2022 | | 2022 |
Enhancing the Generation of Progenitor T-cells from Hematopoietic Stem Cells JM Edgar University of Toronto (Canada), 2018 | | 2018 |
Genipin crosslinked fibrin as a potential bioscaffold for delivering spinal motor neurons derived from human induced pluripotent stem cells M Robinson, A Agbay, SM Willerth, JM Edgar | | |
Differential gene expression and phenotype during motor neuron differentiation of human induced pluripotent stem cells in 3D fibrin scaffolds JM Edgar, M Robinson, A Agbay, SM Willerth | | |