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John M. Edgar
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Progenitor T-cell differentiation from hematopoietic stem cells using Delta-like-4 and VCAM-1
S Shukla, MA Langley, J Singh, JM Edgar, M Mohtashami, ...
Nature Methods 14 (5), 531-538, 2017
1352017
Biomaterial strategies for delivering stem cells as a treatment for spinal cord injury
A Agbay, JM Edgar, M Robinson, T Styan, K Wilson, J Schroll, J Ko, ...
Cells Tissues Organs 202 (1-2), 42-51, 2016
502016
Fibrin Hydrogels Induce Mixed Dorsal/Ventral Spinal Neuron Identities During Differentiation of Human Induced Pluripotent Stem Cells
JM Edgar, M Robinson, SM Willerth
Acta Biomaterialia, 2017
472017
Incorporation of retinoic acid releasing microspheres into pluripotent stem cell aggregates for inducing neuronal differentiation
JC Gomez, JM Edgar, AM Agbay, E Bibault, A Montgomery, NK Mohtaram, ...
Cellular and Molecular Bioengineering 8, 307-319, 2015
332015
DLL4 and VCAM1 enhance the emergence of T cell–competent hematopoietic progenitors from human pluripotent stem cells
YS Michaels, JM Edgar, MC Major, EL Castle, C Zimmerman, T Yin, ...
Science Advances 8 (34), eabn5522, 2022
322022
Multi-objective optimization reveals time-and dose-dependent inflammatory cytokine-mediated regulation of human stem cell derived T-cell development
JM Edgar, YS Michaels, PW Zandstra
NPJ Regenerative Medicine 7 (1), 11, 2022
172022
Sex-biased human thymic architecture guides T cell development through spatially defined niches
LN Stankiewicz, K Salim, EA Flaschner, YX Wang, JM Edgar, LJ Durland, ...
Developmental Cell, 2024
42024
Inflammatory Cytokines Regulate T-cell Development from Blood Progenitor Cells in a Stage and Dose-Specific Manner
JM Edgar, PW Zandstra
bioRxiv, 2021
22021
Time-and lineage-resolved transcriptional profiling uncovers gene expression programs and clonal relationships that underlie human T lineage specification
YS Michaels, MC Major, B Bonham-Carter, J Zhang, T Heydari, JM Edgar, ...
bioRxiv, 2023.10. 06.561277, 2023
12023
Tracking the gene expression programs and clonal relationships that underlie mast, myeloid, and T lineage specification from stem cells
YS Michaels, MC Major, B Bonham-Carter, J Zhang, T Heydari, JM Edgar, ...
Cell Systems, 2024
2024
ENGINEERED, CLINICALLY-RELEVANT PRODUCTION OF HELPER (CD4+) T CELLS FROM PLURIPOTENT STEM CELLS
RD Jones, K Salim, JM Edgar, LN Stankiewicz, L Durland, J Gillies, ...
Cytotherapy 26 (6), S228, 2024
2024
Tunable differentiation of human CD4+ and CD8+ T cells from pluripotent stem cells
RD Jones, K Salim, LN Stankiewicz, JM Edgar, L Leon, JK Gillies, ...
bioRxiv, 2024.10. 29.620998, 2024
2024
Engineering the thymic niche for T-cell differentiation from stem cells
JM Edgar
University of British Columbia, 2023
2023
MEDIA FORMULATIONS AND METHODS FOR PRODUCING PROGENITOR T CELLS
PW Zandstra, JM Edgar
US Patent App. 17/776,575, 2022
2022
Enhancing the Generation of Progenitor T-cells from Hematopoietic Stem Cells
JM Edgar
University of Toronto (Canada), 2018
2018
Genipin crosslinked fibrin as a potential bioscaffold for delivering spinal motor neurons derived from human induced pluripotent stem cells
M Robinson, A Agbay, SM Willerth, JM Edgar
Differential gene expression and phenotype during motor neuron differentiation of human induced pluripotent stem cells in 3D fibrin scaffolds
JM Edgar, M Robinson, A Agbay, SM Willerth
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