Mitochondrial genome variation in eastern Asia and the peopling of Japan M Tanaka, VM Cabrera, AM González, JM Larruga, T Takeyasu, N Fuku, ... Genome research 14 (10a), 1832-1850, 2004 | 642 | 2004 |
Carotid plaque and intima-media thickness assessed by b-mode ultrasonography in subjects ranging from young adults to centenarians S Homma, N Hirose, H Ishida, T Ishii, G Araki Stroke 32 (4), 830-835, 2001 | 485 | 2001 |
Inflammation, but not telomere length, predicts successful ageing at extreme old age: a longitudinal study of semi-supercentenarians Y Arai, CM Martin-Ruiz, M Takayama, Y Abe, T Takebayashi, S Koyasu, ... EBioMedicine 2 (10), 1549-1558, 2015 | 327 | 2015 |
Novel bile acid biosynthetic pathways are enriched in the microbiome of centenarians Y Sato, K Atarashi, DR Plichta, Y Arai, S Sasajima, SM Kearney, W Suda, ... Nature 599 (7885), 458-464, 2021 | 297 | 2021 |
Functional status of centenarians in Tokyo, Japan: developing better phenotypes of exceptional longevity Y Gondo, N Hirose, Y Arai, H Inagaki, Y Masui, K Yamamura, K Shimizu, ... The Journals of Gerontology Series A: Biological Sciences and Medical …, 2006 | 248 | 2006 |
Denture wearing during sleep doubles the risk of pneumonia in the very elderly T Iinuma, Y Arai, Y Abe, M Takayama, M Fukumoto, Y Fukui, T Iwase, ... Journal of dental research 94 (3_suppl), 28S-36S, 2015 | 238 | 2015 |
Single-cell transcriptomics reveals expansion of cytotoxic CD4 T cells in supercentenarians K Hashimoto, T Kouno, T Ikawa, N Hayatsu, Y Miyajima, H Yabukami, ... Proceedings of the National Academy of Sciences 116 (48), 24242-24251, 2019 | 235 | 2019 |
Role of Endothelial Cell–Derived Angptl2 in vascular inflammation leading to endothelial dysfunction and atherosclerosis progression E Horio, T Kadomatsu, K Miyata, Y Arai, K Hosokawa, Y Doi, T Ninomiya, ... Arteriosclerosis, thrombosis, and vascular biology 34 (4), 790-800, 2014 | 177 | 2014 |
A combination of three common inherited mitochondrial DNA polymorphisms promotes longevity in Finnish and Japanese subjects AK Niemi, JS Moilanen, M Tanaka, A Hervonen, M Hurme, T Lehtimäki, ... European Journal of Human Genetics 13 (2), 166-170, 2005 | 157 | 2005 |
Personality and all-cause mortality among older adults dwelling in a Japanese community: A five-year population-based prospective cohort study H Iwasa, Y Masui, Y Gondo, H Inagaki, C Kawaai, T Suzuki The American Journal of Geriatric Psychiatry 16 (5), 399-405, 2008 | 151 | 2008 |
Deep whole-genome sequencing reveals recent selection signatures linked to evolution and disease risk of Japanese Y Okada, Y Momozawa, S Sakaue, M Kanai, K Ishigaki, M Akiyama, ... Nature communications 9 (1), 1631, 2018 | 147 | 2018 |
Association analysis between longevity in the Japanese population and polymorphic variants of genes involved in insulin and insulin-like growth factor 1 signaling pathways T Kojima, H Kamei, T Aizu, Y Arai, M Takayama, S Nakazawa, Y Ebihara, ... Experimental gerontology 39 (11-12), 1595-1598, 2004 | 140 | 2004 |
The impact of leisure activities on older adults’ cognitive function, physical function, and mental health G Sala, D Jopp, F Gobet, M Ogawa, Y Ishioka, Y Masui, H Inagaki, ... PloS one 14 (11), e0225006, 2019 | 132 | 2019 |
Maximum occlusal force and physical performance in the oldest old: the Tokyo oldest old survey on total health T Iinuma, Y Arai, M Fukumoto, M Takayama, Y Abe, K Asakura, ... Journal of the American Geriatrics Society 60 (1), 68-76, 2012 | 131 | 2012 |
Significance of occlusal force for dietary fibre and vitamin intakes in independently living 70-year-old Japanese: from SONIC Study C Inomata, K Ikebe, R Kagawa, H Okubo, S Sasaki, T Okada, H Takeshita, ... Journal of dentistry 42 (5), 556-564, 2014 | 128 | 2014 |
Mitochondrial DNA haplogroup D4a is a marker for extreme longevity in Japan E Bilal, R Rabadan, G Alexe, N Fuku, H Ueno, Y Nishigaki, Y Fujita, M Ito, ... PloS one 3 (6), e2421, 2008 | 124 | 2008 |
APOE Alleles and Extreme Human Longevity P Sebastiani, A Gurinovich, M Nygaard, T Sasaki, B Sweigart, H Bae, ... The Journals of Gerontology: Series A 74 (1), 44-51, 2019 | 118 | 2019 |
RNA editing genes associated with extreme old age in humans and with lifespan in C. elegans P Sebastiani, M Montano, A Puca, N Solovieff, T Kojima, MC Wang, ... PloS one 4 (12), e8210, 2009 | 115 | 2009 |
Age and sex differences in the taste sensitivity of young adult, young‐old and old‐old J apanese M Yoshinaka, K Ikebe, M Uota, T Ogawa, T Okada, C Inomata, ... Geriatrics & gerontology international 16 (12), 1281-1288, 2016 | 111 | 2016 |
Morbidity of Tokyo-area centenarians and its relationship to functional status M Takayama, N Hirose, Y Arai, Y Gondo, K Shimizu, Y Ebihara, ... The Journals of Gerontology Series A: Biological Sciences and Medical …, 2007 | 105 | 2007 |