Hui-Min Zhang
Hui-Min Zhang
Adresse e-mail validée de gene.com
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KIT kinase mutants show unique mechanisms of drug resistance to imatinib and sunitinib in gastrointestinal stromal tumor patients
KS Gajiwala, JC Wu, J Christensen, GD Deshmukh, W Diehl, JP DiNitto, ...
Proceedings of the National Academy of Sciences 106 (5), 1542-1547, 2009
3612009
Epitope mapping of a 95 kDa antigen in complex with antibody by solution-phase amide backbone hydrogen/deuterium exchange monitored by fourier transform ion cyclotron resonance …
Q Zhang, LAN Willison, P Tripathi, SK Sathe, KH Roux, MR Emmett, ...
Analytical chemistry, 2011
1162011
Structural Switch of Lysyl-tRNA Synthetase between Translation and Transcription
Y Ofir-Birin, P Fang, SP Bennett, HM Zhang, J Wang, I Rachmin, ...
Molecular Cell, 2012
1112012
Enhanced digestion efficiency, peptide ionization efficiency, and sequence resolution for protein hydrogen/deuterium exchange monitored by Fourier transform ion cyclotron …
HM Zhang, S Kazazic, TM Schaub, JD Tipton, MR Emmett, AG Marshall
Analytical chemistry 80 (23), 9034-9041, 2008
1002008
Unique domain appended to vertebrate tRNA synthetase is essential for vascular development
X Xu, Y Shi, HM Zhang, EC Swindell, AG Marshall, M Guo, S Kishi, ...
Nature Communications 3, 681, 2012
962012
In vitro and in vivo modifications of recombinant and human IgG antibodies
H Liu, G Ponniah, HM Zhang, C Nowak, A Neill, N Gonzalez-Lopez, ...
mAbs 6 (5), 1145-1154, 2014
872014
Fast reversed-phase liquid chromatography to reduce back exchange and increase throughput in H/D exchange monitored by FT-ICR mass spectrometry
HM Zhang, GM Bou-Assaf, MR Emmett, AG Marshall
Journal of the American Society for Mass Spectrometry 20 (3), 520-524, 2009
662009
Automated data reduction for hydrogen/deuterium exchange experiments, enabled by high-resolution Fourier transform ion cyclotron resonance mass spectrometry
S Kazazic, HM Zhang, TM Schaub, MR Emmett, CL Hendrickson, ...
Journal of the American Society for Mass Spectrometry 21 (4), 550-558, 2010
652010
Dispersed disease-causing neomorphic mutations on a single protein promote the same localized conformational opening
W He, HM Zhang, YE Chong, M Guo, AG Marshall, XL Yang
Proceedings of the National Academy of Sciences 108 (30), 12307-12312, 2011
572011
Simultaneous reduction and digestion of proteins with disulfide bonds for hydrogen/deuterium exchange monitored by mass spectrometry
HM Zhang, SM McLoughlin, SD Frausto, H Tang, MR Emmett, ...
Analytical chemistry 82 (4), 1450-1454, 2010
522010
Mapping of the allosteric network in the regulation of α-isopropylmalate synthase from Mycobacterium tuberculosis by the feedback inhibitor l-leucine: Solution-phase H/D …
PA Frantom, HM Zhang, MR Emmett, AG Marshall, JS Blanchard
Biochemistry 48 (31), 7457-7464, 2009
412009
Computing H/D-Exchange rates of single residues from data of proteolytic fragments
E Althaus, S Canzar, C Ehrler, M Emmett, A Karrenbauer, A Marshall, ...
BMC bioinformatics 11 (1), 424, 2010
382010
Structural context for mobilization of a human tRNA synthetase from its cytoplasmic complex
P Fang, HM Zhang, R Shapiro, AG Marshall, P Schimmel, XL Yang, ...
Proceedings of the National Academy of Sciences 108 (20), 8239-8244, 2011
352011
Nucleotide-induced conformational changes of tetradecameric GroEL mapped by H/D exchange monitored by FT-ICR mass spectrometry
Q Zhang, J Chen, K Kuwajima, HM Zhang, F Xian, NL Young, ...
Scientific reports 3, 2013
342013
Drug binding and resistance mechanism of KIT tyrosine kinase revealed by hydrogen/deuterium exchange FTICR mass spectrometry
HM Zhang, X Yu, MJ Greig, KS Gajiwala, JC Wu, W Diehl, EA Lunney, ...
Protein Science 19 (4), 703-715, 2010
282010
Computing H/D-exchange speeds of single residues from data of peptic fragments
E Althaus, S Canzar, MR Emmett, A Karrenbauer, AG Marshall, ...
Proceedings of the 2008 ACM symposium on Applied computing, 1273-1277, 2008
222008
Uncovering of a short internal peptide activates a tRNA synthetase procytokine
PS Lee, HM Zhang, AG Marshall, XL Yang, P Schimmel
Journal of Biological Chemistry 287 (24), 20504-20508, 2012
122012
Warfarin untargeted metabolomics study identifies novel procoagulant ethanolamide plasma lipids
H Deguchi, DJ Elias, S Trauger, HM Zhang, E Kalisiak, G Siuzdak, ...
British journal of haematology 165 (3), 409-412, 2014
112014
Discrete fitting of hydrogen-deuterium-exchange data of overlapping fragments
E Althaus, S Canzar, C Ehrler, M Emmett, A Karrenbauer, A Marshall, ...
BIOCOMP, 496-502, 2009
82009
In vitro and in vivo modifications of recombinant and human IgG antibodies. MAbs 2014; 6: 1145-54; PMID: 25517300
H Liu, G Ponniah, HM Zhang, C Nowak, A Neill, N Gonzalez-Lopez, ...
5
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