Structure and function of the nucleosome-binding PWWP domain S Qin, J Min Trends in biochemical sciences 39 (11), 536-547, 2014 | 189 | 2014 |
A cellular chemical probe targeting the chromodomains of Polycomb repressive complex 1 JI Stuckey, BM Dickson, N Cheng, Y Liu, JL Norris, SH Cholensky, ... Nature chemical biology 12 (3), 180-187, 2016 | 157 | 2016 |
H3K14ac is linked to methylation of H3K9 by the triple Tudor domain of SETDB1 RZ Jurkowska, S Qin, G Kungulovski, W Tempel, Y Liu, P Bashtrykov, ... Nature Communications 8 (1), 2057, 2017 | 77 | 2017 |
Recognition of unmodified histone H3 by the first PHD finger of bromodomain-PHD finger protein 2 provides insights into the regulation of histone acetyltransferases monocytic … S Qin, L Jin, J Zhang, L Liu, P Ji, M Wu, J Wu, Y Shi Journal of Biological Chemistry 286 (42), 36944-36955, 2011 | 69 | 2011 |
Tudor domains of the PRC2 components PHF1 and PHF19 selectively bind to histone H3K36me3 S Qin, Y Guo, C Xu, C Bian, M Fu, S Gong, J Min Biochemical and biophysical research communications 430 (2), 547-553, 2013 | 60 | 2013 |
Epigenetic targets and drug discovery: part 1: histone methylation Y Liu, K Liu, S Qin, C Xu, J Min Pharmacology & therapeutics 143 (3), 275-294, 2014 | 55 | 2014 |
Solution structure of an atypical PHD finger in BRPF2 and its interaction with DNA L Liu, S Qin, J Zhang, P Ji, Y Shi, J Wu Journal of structural biology 180 (1), 165-173, 2012 | 54 | 2012 |
Family-wide characterization of histone binding abilities of human CW domain-containing proteins Y Liu, W Tempel, Q Zhang, X Liang, P Loppnau, S Qin, J Min Journal of Biological Chemistry 291 (17), 9000-9013, 2016 | 53 | 2016 |
Structural basis for substrate recognition by the human N-terminal methyltransferase 1 C Dong, Y Mao, W Tempel, S Qin, L Li, P Loppnau, R Huang, J Min Genes & Development 29 (22), 2343-2348, 2015 | 46 | 2015 |
Structural basis for histone mimicry and hijacking of host proteins by influenza virus protein NS1 S Qin, Y Liu, W Tempel, MS Eram, C Bian, K Liu, G Senisterra, L Crombet, ... Nature communications 5 (1), 3952, 2014 | 43 | 2014 |
A chemical probe targeting the PWWP domain alters NSD2 nucleolar localization D Dilworth, RP Hanley, R Ferreira de Freitas, A Allali-Hassani, M Zhou, ... Nature chemical biology 18 (1), 56-63, 2022 | 41 | 2022 |
Structural basis for the regulatory role of the PPxY motifs in the thioredoxin-interacting protein TXNIP Y Liu, J Lau, W Li, W Tempel, L Li, A Dong, A Narula, S Qin, J Min Biochemical Journal 473 (2), 179-187, 2016 | 41 | 2016 |
Structural insights into trans-histone regulation of H3K4 methylation by unique histone H4 binding of MLL3/4 Y Liu, S Qin, TY Chen, M Lei, SS Dhar, JC Ho, A Dong, P Loppnau, Y Li, ... Nature communications 10 (1), 36, 2019 | 35 | 2019 |
Crystal structure of human BS69 Bromo-ZnF-PWWP reveals its role in H3K36me3 nucleosome binding J Wang, S Qin, F Li, S Li, W Zhang, J Peng, Z Zhang, Q Gong, J Wu, Y Shi Cell research 24 (7), 890-893, 2014 | 35 | 2014 |
Peptide recognition by heterochromatin protein 1 (HP1) chromoshadow domains revisited: Plasticity in the pseudosymmetric histone binding site of human HP1 Y Liu, S Qin, M Lei, W Tempel, Y Zhang, P Loppnau, Y Li, J Min Journal of Biological Chemistry 292 (14), 5655-5664, 2017 | 32 | 2017 |
Solution Structure of S. cerevisiae PDCD5-Like Protein and Its Promoting Role in H2O2-Induced Apoptosis in Yeast J Hong, J Zhang, Z Liu, S Qin, J Wu, Y Shi Biochemistry 48 (29), 6824-6834, 2009 | 23 | 2009 |
Structural and functional analysis of the DOT1L–AF10 complex reveals mechanistic insights into MLL-AF10-associated leukemogenesis H Zhang, B Zhou, S Qin, J Xu, R Harding, W Tempel, V Nayak, Y Li, ... Genes & development 32 (5-6), 341-346, 2018 | 18 | 2018 |
Crystal structure of the BRPF2 PWWP domain in complex with DNA reveals a different binding mode than the HDGF family of PWWP domains M Zhang, M Lei, S Qin, A Dong, A Yang, Y Li, P Loppnau, TR Hughes, ... Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1864 (3), 194688, 2021 | 13 | 2021 |
A small molecule antagonist of SMN disrupts the interaction between SMN and RNAP II Y Liu, A Iqbal, W Li, Z Ni, Y Wang, J Ramprasad, KJ Abraham, M Zhang, ... Nature communications 13 (1), 5453, 2022 | 12 | 2022 |
Predicting pore-water pressure in front of a TBM using a deep learning approach S Qin, T Xu, WH Zhou International Journal of Geomechanics 21 (8), 04021140, 2021 | 12 | 2021 |