Hayarpi Torosyan
Hayarpi Torosyan
PhD Candidate, UCSF
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Cited by
Cited by
An aggregation advisor for ligand discovery
JJ Irwin, D Duan, H Torosyan, AK Doak, KT Ziebart, T Sterling, ...
Journal of medicinal chemistry 58 (17), 7076-7087, 2015
The activities of drug inactive ingredients on biological targets
J Pottel, D Armstrong, L Zou, A Fekete, XP Huang, H Torosyan, ...
Science 369 (6502), 403-413, 2020
Structure-based discovery of selective positive allosteric modulators of antagonists for the M2 muscarinic acetylcholine receptor
M Korczynska, MJ Clark, C Valant, J Xu, EV Moo, S Albold, DR Weiss, ...
Proceedings of the National Academy of Sciences 115 (10), E2419-E2428, 2018
Stable colloidal drug aggregates catch and release active enzymes
CK McLaughlin, D Duan, AN Ganesh, H Torosyan, BK Shoichet, ...
ACS chemical biology 11 (4), 992-1000, 2016
Internal structure and preferential protein binding of colloidal aggregates
D Duan, H Torosyan, D Elnatan, CK McLaughlin, J Logie, MS Shoichet, ...
ACS chemical biology 12 (1), 282-290, 2017
Identification of novel smoothened ligands using structure-based docking
C Lacroix, I Fish, H Torosyan, P Parathaman, JJ Irwin, BK Shoichet, ...
PLoS One 11 (8), e0160365, 2016
Protein stability effects in aggregate-based enzyme inhibition
H Torosyan, BK Shoichet
Journal of medicinal chemistry 62 (21), 9593-9599, 2019
Structure-based approach for identification of novel phenylboronic acids as serine-β-lactamase inhibitors
J Sgrignani, F De Luca, H Torosyan, JD Docquier, D Duan, B Novati, ...
Journal of computer-aided molecular design 30, 851-861, 2016
Therapeutic implications of activating noncanonical PIK3CA mutations in head and neck squamous cell carcinoma
N Jin, B Keam, J Cho, MJ Lee, HR Kim, H Torosyan, N Jura, PKS Ng, ...
The Journal of clinical investigation 131 (22), 2021
Robust Sequence Determinants of α-Synuclein Toxicity in Yeast Implicate Membrane Binding
RW Newberry, T Arhar, J Costello, GC Hartoularos, AM Maxwell, ...
ACS chemical biology 15 (8), 2137-2153, 2020
Triggered release enhances the cytotoxicity of stable colloidal drug aggregates
EN Donders, AN Ganesh, H Torosyan, P Lak, BK Shoichet, MS Shoichet
ACS chemical biology 14 (7), 1507-1514, 2019
CNPY4 inhibits the Hedgehog pathway by modulating membrane sterol lipids
M Lo, A Sharir, MD Paul, H Torosyan, C Agnew, A Li, C Neben, ...
Nature Communications 13 (1), 2407, 2022
Piquing our interest: Insights into the role of PEAK3 in signaling and disease
MD Paul, H Torosyan, N Jura
Science signaling 15 (722), eabm9396, 2022
Stable colloidal drug aggregates and methods of manufacture and use thereof
MS Shoichet, AN Ganesh, EN Donders, BK Shoichet, H Torosyan
US Patent App. 17/619,837, 2022
Structural insights into regulation of the PEAK3 pseudokinase scaffold by 14-3-3
H Torosyan, MD Paul, A Forget, M Lo, D Diwanji, K Pawłowski, NJ Krogan, ...
Structural insights into regulation of the PEAK3 scaffold by 14-3-3
H Torosyan, MD Paul, A Forget, M Lo, D Diwanji, K Pawlowski, NJ Krogan, ...
bioRxiv, 2022.09. 01.506268, 2022
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