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| Spatially distinct tumor immune microenvironments stratify triple-negative breast cancers T Gruosso, M Gigoux, VSK Manem, N Bertos, D Zuo, I Perlitch, SMI Saleh, ... The Journal of clinical investigation 129 (4), 1785-1800, 2019 | 322 | 2019 |
| Metabolic profiling using stable isotope tracing reveals distinct patterns of glucose utilization by physiologically activated CD8+ T cells EH Ma, MJ Verway, RM Johnson, DG Roy, M Steadman, S Hayes, ... Immunity 51 (5), 856-870. e5, 2019 | 291 | 2019 |
| PGC-1α promotes breast cancer metastasis and confers bioenergetic flexibility against metabolic drugs S Andrzejewski, E Klimcakova, RM Johnson, S Tabariès, MG Annis, ... Cell metabolism 26 (5), 778-787. e5, 2017 | 234 | 2017 |
| Rapid and efficient generation of oligodendrocytes from human induced pluripotent stem cells using transcription factors M Ehrlich, S Mozafari, M Glatza, L Starost, S Velychko, AL Hallmann, ... Proceedings of the National Academy of Sciences 114 (11), E2243-E2252, 2017 | 229 | 2017 |
| Methionine metabolism shapes T helper cell responses through regulation of epigenetic reprogramming DG Roy, J Chen, V Mamane, EH Ma, BM Muhire, RD Sheldon, ... Cell metabolism 31 (2), 250-266. e9, 2020 | 221 | 2020 |
| Zebrafish screen identifies novel compound with selective toxicity against leukemia S Ridges, WL Heaton, D Joshi, H Choi, A Eiring, L Batchelor, P Choudhry, ... Blood, The Journal of the American Society of Hematology 119 (24), 5621-5631, 2012 | 168 | 2012 |
| Immature low-density neutrophils exhibit metabolic flexibility that facilitates breast cancer liver metastasis BE Hsu, S Tabariès, RM Johnson, S Andrzejewski, J Senecal, C Lehuédé, ... Cell reports 27 (13), 3902-3915. e6, 2019 | 167 | 2019 |
| The receptor tyrosine kinase AXL is required at multiple steps of the metastatic cascade during HER2-positive breast cancer progression MA Goyette, S Duhamel, L Aubert, A Pelletier, P Savage, MP Thibault, ... Cell reports 23 (5), 1476-1490, 2018 | 141 | 2018 |
| CDK4/6 inhibitors target SMARCA4-determined cyclin D1 deficiency in hypercalcemic small cell carcinoma of the ovary Y Xue, B Meehan, E Macdonald, S Venneti, XQD Wang, L Witkowski, ... Nature communications 10 (1), 558, 2019 | 111 | 2019 |
| Comprehensive profiling of poor-risk paired primary and recurrent triple-negative breast cancers reveals immune phenotype shifts KE Hutchinson, SE Yost, CW Chang, RM Johnson, AR Carr, PR McAdam, ... Clinical Cancer Research 26 (3), 657-668, 2020 | 86 | 2020 |
| Targeting EZH2 reactivates a breast cancer subtype-specific anti-metastatic transcriptional program A Hirukawa, HW Smith, D Zuo, CR Dufour, P Savage, N Bertos, ... Nature communications 9 (1), 2547, 2018 | 79 | 2018 |
| The miR-17∼ 92 microRNA cluster is a global regulator of tumor metabolism S Izreig, B Samborska, RM Johnson, A Sergushichev, EH Ma, C Lussier, ... Cell reports 16 (7), 1915-1928, 2016 | 70 | 2016 |
| CCNE1 amplification is associated with poor prognosis in patients with triple negative breast cancer ZM Zhao, SE Yost, KE Hutchinson, SM Li, YC Yuan, J Noorbakhsh, Z Liu, ... BMC cancer 19, 1-11, 2019 | 66 | 2019 |
| Venous thromboembolism in brain tumors: risk factors, molecular mechanisms, and clinical challenges J Riedl, C Ay Seminars in thrombosis and hemostasis 45 (04), 334-341, 2019 | 58 | 2019 |
| LKB1 deficiency in T cells promotes the development of gastrointestinal polyposis MC Poffenberger, A Metcalfe-Roach, E Aguilar, J Chen, BE Hsu, ... Science 361 (6400), 406-411, 2018 | 54 | 2018 |
| Cancer-associated fibroblasts require proline synthesis by PYCR1 for the deposition of pro-tumorigenic extracellular matrix EJ Kay, K Paterson, C Riera-Domingo, D Sumpton, JHM Däbritz, ... Nature metabolism 4 (6), 693-710, 2022 | 51 | 2022 |
| Inhibition of the stromal p38MAPK/MK2 pathway limits breast cancer metastases and chemotherapy-induced bone loss B Murali, Q Ren, X Luo, DV Faget, C Wang, RM Johnson, T Gruosso, ... Cancer research 78 (19), 5618-5630, 2018 | 49 | 2018 |
| KIBRA (WWC1) is a metastasis suppressor gene affected by chromosome 5q loss in triple-negative breast cancer JF Knight, VYC Sung, E Kuzmin, AL Couzens, DA de Verteuil, ... Cell reports 22 (12), 3191-3205, 2018 | 47 | 2018 |
| Sublethal oligodendrocyte injury: A reversible condition in multiple sclerosis? QL Cui, D Khan, M Rone, V TS Rao, RM Johnson, YH Lin, PA Bilodeau, ... Annals of neurology 81 (6), 811-824, 2017 | 39 | 2017 |
Russell G JonesVan Andel Research InstituteAdresse e-mail validée de vai.org
