Thomas Simmen
Thomas Simmen
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PACS-2 controls endoplasmic reticulum–mitochondria communication and Bid-mediated apoptosis
T Simmen, JE Aslan, AD Blagoveshchenskaya, L Thomas, L Wan, ...
The EMBO journal 24 (4), 717-729, 2005
Increased ER–mitochondrial coupling promotes mitochondrial respiration and bioenergetics during early phases of ER stress
R Bravo, JM Vicencio, V Parra, R Troncoso, JP Munoz, M Bui, C Quiroga, ...
J Cell Sci 124 (13), 2143-2152, 2011
Where the endoplasmic reticulum and the mitochondrion tie the knot: The mitochondria-associated membrane (MAM)
A Raturi, T Simmen
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1833 (1), 213-224, 2013
ERp44, a novel endoplasmic reticulum folding assistant of the thioredoxin family
T Anelli, M Alessio, A Mezghrani, T Simmen, F Talamo, A Bachi, R Sitia
The EMBO journal 21 (4), 835-844, 2002
Manipulation of oxidative protein folding and PDI redox state in mammalian cells
A Mezghrani, A Fassio, A Benham, T Simmen, I Braakman, R Sitia
The EMBO journal 20 (22), 6288-6296, 2001
AP-4 binds basolateral signals and participates in basolateral sorting in epithelial MDCK cells
T Simmen, S Höning, A Icking, R Tikkanen, W Hunziker
Nature cell biology 4 (2), 154-159, 2002
Thiol-mediated protein retention in the endoplasmic reticulum: the role of ERp44
T Anelli, M Alessio, A Bachi, L Bergamelli, G Bertoli, S Camerini, ...
The EMBO journal 22 (19), 5015-5022, 2003
Trafficking of TRPP2 by PACS proteins represents a novel mechanism of ion channel regulation
M Köttgen, T Benzing, T Simmen, R Tauber, B Buchholz, S Feliciangeli, ...
The EMBO journal 24 (4), 705-716, 2005
ERdj5, an endoplasmic reticulum (ER)-resident protein containing DnaJ and thioredoxin domains, is expressed in secretory cells or following ER stress
PM Cunnea, A Miranda-Vizuete, G Bertoli, T Simmen, ...
Journal of Biological Chemistry 278 (2), 1059-1066, 2003
Oxidative protein folding in the endoplasmic reticulum: tight links to the mitochondria-associated membrane (MAM)
T Simmen, EM Lynes, K Gesson, G Thomas
Biochimica et Biophysica Acta (BBA)-Biomembranes 1798 (8), 1465-1473, 2010
The subcellular distribution of calnexin is mediated by PACS-2
N Myhill, EM Lynes, JA Nanji, AD Blagoveshchenskaya, H Fei, ...
Molecular biology of the cell 19 (7), 2777-2788, 2008
Palmitoylated TMX and calnexin target to the mitochondria‐associated membrane
EM Lynes, M Bui, MC Yap, MD Benson, B Schneider, L Ellgaard, ...
The EMBO journal 31 (2), 457-470, 2012
Rab32 modulates apoptosis onset and mitochondria-associated membrane (MAM) properties
M Bui, SY Gilady, REB Fitzsimmons, MD Benson, EM Lynes, K Gesson, ...
Journal of Biological Chemistry 285 (41), 31590-31602, 2010
Ero1α requires oxidizing and normoxic conditions to localize to the mitochondria-associated membrane (MAM)
SY Gilady, M Bui, EM Lynes, MD Benson, R Watts, JE Vance, T Simmen
Cell Stress and Chaperones 15 (5), 619-629, 2010
Urban planning of the endoplasmic reticulum (ER): how diverse mechanisms segregate the many functions of the ER
EM Lynes, T Simmen
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1813 (10), 1893-1905, 2011
Palmitoylation is the switch that assigns calnexin to quality control or ER Ca2+ signaling
EM Lynes, A Raturi, M Shenkman, CO Sandoval, MC Yap, J Wu, ...
J Cell Sci 126 (17), 3893-3903, 2013
The chemotherapeutic agent paclitaxel inhibits autophagy through two distinct mechanisms that regulate apoptosis
RA Veldhoen, SL Banman, DR Hemmerling, R Odsen, T Simmen, ...
Oncogene 32 (6), 736-746, 2013
Dimerization-dependent green and yellow fluorescent proteins
SC Alford, Y Ding, T Simmen, RE Campbell
ACS synthetic biology 1 (12), 569-575, 2012
Coming together to define membrane contact sites
L Scorrano, MA De Matteis, S Emr, F Giordano, G Hajnóczky, B Kornmann, ...
Nature communications 10 (1), 1-11, 2019
The tyrosinase tail mediates sorting to the lysosomal compartment in MDCK cells via a di-leucine and a tyrosine-based signal
T Simmen, A Schmidt, W Hunziker, F Beermann
Journal of cell science 112 (1), 45-53, 1999
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