Mychael Lourenco

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Sergio T. FerreiraInstitute of Biophysics Carlos Chagas Filho & Institute of Medical Biochemistry Leopoldo de MeisVerified email at bioqmed.ufrj.br
Paulo MattosMD, PhD, D'Or Institute for Research and Education (IDOR)Verified email at idor.org
Fernanda Tovar MollMD, PhD, D'Or Institute for Research and Education (IDOR)Verified email at idor.org
Jorge PB Marcondes de SouzaUniversidade Federal do Rio de JaneiroVerified email at hucff.ufrj.br
Leticia Forny-GermanoPost Doctoral researchVerified email at bioqmed.ufrj.br
Mauricio Martins OliveiraNew York UniversityVerified email at nyu.edu
William KleinNorthwestern UniversityVerified email at northwestern.edu
Eduardo R. ZimmerAssistant Professor, UFRGSVerified email at ufrgs.br
Nirma D PereraUniversity of MelbourneVerified email at florey.edu.au
Rajkumar VermaUConn HealthVerified email at uchc.edu
Mario de la Fuente RevengaVCU HealthVerified email at vcuhealth.org
Constanze SeidenbecherLeibniz-Institut für NeurobiologieVerified email at lin-magdeburg.de
JH LedoMedical University of South CarolinaVerified email at musc.edu
Claudia Kimie SuemotoAssociate Professor, Division of Geriatrics, University of Sao Paulo Medical SchoolVerified email at usp.br
Lea Tenenholz GrinbergUniversity of California, San FranciscoVerified email at ucsf.edu
Renata Elaine Paraizo LeiteFaculdade de Medicina da Universidade de São PauloVerified email at usp.br
Olavo B. AmaralProfessor, Institute of Medical Biochemistry Leopoldo de Meis, Federal University of Rio de Janeiro.Verified email at bioqmed.ufrj.br
Jean-Christophe HouzelICB Univ Federal do Rio de Janeiro,Verified email at icb.ufrj.br
Douglas MunozProfessor, Canada Research Chair in Neuroscience, Queen's UniversityVerified email at queensu.ca
Andre Felipe BatistaPostdoctoral Research FellowVerified email at bwh.harvard.edu

Mychael Lourenco

Assistant Professor at Federal University of Rio de Janeiro

Verified email at bioqmed.ufrj.br - Homepage

Neuroscience Alzheimer's disease neurodegeneration protein synthesis hormones


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Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer’s models MV Lourenco, RL Frozza, GB de Freitas, H Zhang, GC Kincheski, ... Nature medicine 25 (1), 165-175, 2019	679	2019
Soluble amyloid-β oligomers as synaptotoxins leading to cognitive impairment in Alzheimer’s disease ST Ferreira, MV Lourenco, MM Oliveira, FG De Felice Frontiers in cellular neuroscience 9, 191, 2015	415	2015
How does brain insulin resistance develop in Alzheimer's disease? FG De Felice, MV Lourenco, ST Ferreira Alzheimer's & Dementia 10 (1), S26-S32, 2014	411	2014
TNF-α mediates PKR-dependent memory impairment and brain IRS-1 inhibition induced by Alzheimer’s β-amyloid oligomers in mice and monkeys MV Lourenco, JR Clarke, RL Frozza, TR Bomfim, L Forny-Germano, ... Cell metabolism 18 (6), 831-843, 2013	390	2013
Synaptopathies: synaptic dysfunction in neurological disorders – A review from students to students K Lepeta, MV Lourenco, BC Schweitzer, PV Martino Adami, P Banerjee, ... Journal of neurochemistry 138 (6), 785-805, 2016	307	2016
d-serine levels in Alzheimer’s disease: implications for novel biomarker development C Madeira, MV Lourenco, C Vargas-Lopes, CK Suemoto, CO Brandão, ... Translational psychiatry 5 (5), e561-e561, 2015	201	2015
Challenges for Alzheimer's disease therapy: insights from novel mechanisms beyond memory defects RL Frozza, MV Lourenco, FG De Felice Frontiers in neuroscience 12, 334515, 2018	170	2018
Brain metabolic stress and neuroinflammation at the basis of cognitive impairment in Alzheimer’s disease FG De Felice, MV Lourenco Frontiers in aging neuroscience 7, 94, 2015	116	2015
Interaction of amyloid-β (Aβ) oligomers with neurexin 2α and neuroligin 1 mediates synapse damage and memory loss in mice J Brito-Moreira, MV Lourenco, MM Oliveira, FC Ribeiro, JH Ledo, LP Diniz, ... Journal of Biological Chemistry 292 (18), 7327-7337, 2017	88	2017
Neuronal stress signaling and eIF2α phosphorylation as molecular links between Alzheimer's disease and diabetes MV Lourenco, ST Ferreira, FG De Felice Progress in neurobiology 129, 37-57, 2015	83	2015
Metabolic dysfunction in Alzheimer’s disease: from basic neurobiology to clinical approaches JR Clarke, FC Ribeiro, RL Frozza, FG De Felice, MV Lourenco Journal of Alzheimer's Disease 64 (s1), S405-S426, 2018	81	2018
Correction of eIF2-dependent defects in brain protein synthesis, synaptic plasticity, and memory in mouse models of Alzheimer’s disease MM Oliveira, MV Lourenco, F Longo, NP Kasica, W Yang, G Ureta, ... Science signaling 14 (668), eabc5429, 2021	80	2021
Amyloid‐β oligomers in cellular models of Alzheimer’s disease IC Fontana, AR Zimmer, AS Rocha, G Gosmann, DO Souza, MV Lourenco, ... Journal of Neurochemistry 155 (4), 348-369, 2020	69	2020
Protective actions of exercise‐related FNDC5/Irisin in memory and Alzheimer’s disease GB de Freitas, MV Lourenco, FG De Felice Journal of Neurochemistry 155 (6), 602-611, 2020	64	2020
Cerebrospinal fluid irisin correlates with amyloid‐β, BDNF, and cognition in Alzheimer's disease MV Lourenco, FC Ribeiro, FK Sudo, C Drummond, N Assunção, ... Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring 12 (1 …, 2020	64	2020
Amyloid-β oligomers transiently inhibit AMP-activated kinase and cause metabolic defects in hippocampal neurons GSS da Silva, HM Melo, MV Lourenco, NML e Silva, MB De Carvalho, ... Journal of Biological Chemistry 292 (18), 7395-7406, 2017	55	2017
The next 50 years of Neuroscience CM Altimus, BJ Marlin, NE Charalambakis, A Colón-Rodriquez, EJ Glover, ... Journal of Neuroscience 40 (1), 101-106, 2020	48	2020
The malleable brain: plasticity of neural circuits and behavior – A review from students to students N Schaefer, C Rotermund, EM Blumrich, MV Lourenco, P Joshi, ... Journal of neurochemistry 142 (6), 790-811, 2017	45	2017
How does the skeletal muscle communicate with the brain in health and disease? AR Isaac, R Lima-Filho, MV Lourenco Neuropharmacology, 108744, 2021	39	2021
Targeting Alzheimer's pathology through PPARγ signaling: Modulation of microglial function MV Lourenco, JH Ledo Journal of Neuroscience 33 (12), 5083-5084, 2013	26	2013

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