Lisandro H. Otero
Lisandro H. Otero
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How allosteric control of Staphylococcus aureus penicillin binding protein 2a enables methicillin resistance and physiological function
LH Otero, A Rojas-Altuve, LI Llarrull, C Carrasco-López, M Kumarasiri, ...
Proceedings of the National Academy of Sciences 110 (42), 16808-16813, 2013
Discovery of Antibiotic (E)-3-(3-Carboxyphenyl)-2-(4-cyanostyryl)quinazolin-4(3H)-one
R Bouley, M Kumarasiri, Z Peng, LH Otero, W Song, MA Suckow, ...
Journal of the American Chemical Society 137 (5), 1738-1741, 2015
Disruption of allosteric response as an unprecedented mechanism of resistance to antibiotics
J Fishovitz, A Rojas-Altuve, LH Otero, M Dawley, C Carrasco-López, ...
Journal of the American Chemical Society 136 (28), 9814-9817, 2014
Structure of the full-length bacteriophytochrome from the plant pathogen Xanthomonas campestris provides clues to its long-range signaling mechanism
LH Otero, S Klinke, J Rinaldi, F Velázquez-Escobar, MA Mroginski, ...
Journal of molecular biology 428 (19), 3702-3720, 2016
Structural basis for the broad specificity of a new family of amino-acid racemases
A Espaillat, C Carrasco-López, N Bernardo-García, N Pietrosemoli, ...
Acta Crystallographica Section D: Biological Crystallography 70 (1), 79-90, 2014
Development of a hyperimmune equine serum therapy for COVID-19 in Argentina
V Zylberman, S Sanguineti, A Pontoriero, SV Higa, ML Cerutti, ...
Medicina (Buenos Aires), 2020
A Pseudomonas aeruginosa PAO1 acetylcholinesterase is encoded by the PA4921 gene and belongs to the SGNH hydrolase family
DG Sánchez, LH Otero, CM Hernández, AL Serra, S Encarnación, ...
Microbiological research 167 (6), 317-325, 2012
The disruptive effect of lysozyme on the bacterial cell wall explored by an in‐silico structural outlook
ED Primo, LH Otero, F Ruiz, S Klinke, W Giordano
Biochemistry and Molecular Biology Education 46 (1), 83-90, 2018
The reaction mechanism of metallo-β-lactamases is tuned by the conformation of an active-site mobile loop
AR Palacios, MF Mojica, E Giannini, MA Taracila, CR Bethel, PM Alzari, ...
Antimicrobial agents and chemotherapy 63 (1), e01754-18, 2018
Critical active-site residues identified by site-directed mutagenesis in Pseudomonas aeruginosa phosphorylcholine phosphatase, a new member of the haloacid dehalogenases …
PR Beassoni, LH Otero, MJ Massimelli, AT Lisa, CE Domenech
Current Microbiology 53 (6), 534-539, 2006
Snapshots of conformational changes shed light into the NtrX receiver domain signal transduction mechanism
I Fernández, LH Otero, S Klinke, M del Carmen Carrica, FA Goldbaum
Journal of molecular biology 427 (20), 3258-3272, 2015
Using a molecular model and kinetic experiments in the presence of divalent cations to study the active site and catalysis of Pseudomonas aeruginosa phosphorylcholine phosphatase
PR Beassoni, LH Otero, AT Lisa, CE Domenech
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1784 (12), 2038-2044, 2008
A glance on Pseudomonas aeruginosa phosphorylcholine phosphatase, an enzyme whose synthesis depends on the presence of choline in its environment
AT Lisa, PR Beassoni, MJ Massimelli, LH Otero, CE Doménech
Communicating current research and educational topics and trends in applied …, 2007
Crystallization and preliminary X-ray characterization of the full-length bacteriophytochrome from the plant pathogen Xanthomonas campestris pv. campestris
S Klinke, LH Otero, J Rinaldi, S Sosa, BG Guimarães, WE Shepard, ...
Acta Crystallographica Section F: Structural Biology Communications 70 (12 …, 2014
Transition from octahedral to tetrahedral geometry causes the activation or inhibition by Zn 2+ of Pseudomonas aeruginosa phosphorylcholine phosphatase
LH Otero, PR Beassoni, AT Lisa, CE Domenech
BioMetals 23 (2), 307-314, 2010
The structural domains of Pseudomonas aeruginosa phosphorylcholine phosphatase cooperate in substrate hydrolysis: 3D structure and enzymatic mechanism
L Infantes, LH Otero, PR Beassoni, C Boetsch, AT Lisa, CE Domenech, ...
Journal of molecular biology 423 (4), 503-514, 2012
Site-directed mutations and kinetic studies show key residues involved in alkylammonium interactions and reveal two sites for phosphorylcholine in Pseudomonas aeruginosa …
PR Beassoni, LH Otero, C Boetsch, CE Domenech, FD González-Nilo, ...
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1814 (7), 858-863, 2011
Phosphorylcholine phosphatase: a peculiar enzyme of Pseudomonas aeruginosa
CE Domenech, LH Otero, PR Beassoni, AT Lisa
Enzyme research 2011, 2011
Draft genome sequence of Methylobacterium sp. strain V23, isolated from accretion ice of the Antarctic subglacial Lake Vostok
A Sapp, JC Huguet-Tapia, M Sánchez-Lamas, GT Antelo, ED Primo, ...
Genome announcements 6 (10), e00145-18, 2018
Different effects of Mg2+ and Zn2+ on the two sites for alkylammonium compounds in Pseudomonas aeruginosa phosphorylcholine phosphatase
LH Otero, PR Beassoni, C Boetsch, AT Lisa, CE Domenech
Enzyme research 2011, 2011
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