| Evolution of genes and genomes on the Drosophila phylogeny Drosophila 12 Genomes Consortium Nature 450 (7167), 203, 2007 | 1859 | 2007 |
| The distribution of fitness effects of new mutations A Eyre-Walker, PD Keightley Nature Reviews Genetics 8 (8), 610-618, 2007 | 1003 | 2007 |
| Understanding quantitative genetic variation NH Barton, PD Keightley Nature Reviews Genetics 3 (1), 11-21, 2002 | 716 | 2002 |
| High genomic deleterious mutation rates in hominids A Eyre-Walker, PD Keightley Nature 397 (6717), 344-347, 1999 | 441 | 1999 |
| Enhanced CpG mutability and tumorigenesis in MBD4-deficient mice CB Millar, J Guy, OJ Sansom, J Selfridge, E MacDougall, B Hendrich, ... Science 297 (5580), 403-405, 2002 | 349 | 2002 |
| Direct estimation of per nucleotide and genomic deleterious mutation rates in Drosophila C Haag-Liautard, M Dorris, X Maside, S Macaskill, DL Halligan, ... Nature 445 (7123), 82-85, 2007 | 346 | 2007 |
| Estimating the rate of adaptive molecular evolution in the presence of slightly deleterious mutations and population size change A Eyre-Walker, PD Keightley Molecular biology and evolution 26 (9), 2097-2108, 2009 | 329 | 2009 |
| Interference among deleterious mutations favours sex and recombination in finite populations PD Keightley, SP Otto Nature 443 (7107), 89-92, 2006 | 304 | 2006 |
| Analysis of the genome sequences of three Drosophila melanogaster spontaneous mutation accumulation lines PD Keightley, U Trivedi, M Thomson, F Oliver, S Kumar, ML Blaxter Genome research 19 (7), 1195-1201, 2009 | 285 | 2009 |
| Spontaneous mutation accumulation studies in evolutionary genetics DL Halligan, PD Keightley Annual Review of Ecology, Evolution, and Systematics 40, 151-172, 2009 | 279 | 2009 |
| Joint inference of the distribution of fitness effects of deleterious mutations and population demography based on nucleotide polymorphism frequencies PD Keightley, A Eyre-Walker Genetics 177 (4), 2251-2261, 2007 | 277 | 2007 |
| The distribution of mutation effects on viability in Drosophila melanogaster. PD Keightley Genetics 138 (4), 1315-1322, 1994 | 258 | 1994 |
| Direct estimation of the mitochondrial DNA mutation rate in Drosophila melanogaster C Haag-Liautard, N Coffey, D Houle, M Lynch, B Charlesworth, ... PLoS biology 6 (8), 2008 | 257 | 2008 |
| Ubiquitous selective constraints in the Drosophila genome revealed by a genome-wide interspecies comparison DL Halligan, PD Keightley Genome research 16 (7), 875-884, 2006 | 234 | 2006 |
| Deleterious mutations and the evolution of sex PD Keightley, A Eyre-Walker Science 290 (5490), 331-333, 2000 | 231 | 2000 |
| Genomic mutation rates for lifetime reproductive output and lifespan in Caenorhabditis elegans PD Keightley, A Caballero Proceedings of the National Academy of Sciences 94 (8), 3823-3827, 1997 | 221 | 1997 |
| Evidence for widespread degradation of gene control regions in hominid genomes PD Keightley, MJ Lercher, A Eyre-Walker PLoS biology 3 (2), 2005 | 217 | 2005 |
| Quantifying the slightly deleterious mutation model of molecular evolution A Eyre-Walker, PD Keightley, NGC Smith, D Gaffney Molecular Biology and Evolution 19 (12), 2142-2149, 2002 | 185 | 2002 |
| Nature of deleterious mutation load in Drosophila PD Keightley Genetics 144 (4), 1993-1999, 1996 | 159 | 1996 |
| A pleiotropic nonadditive model of variation in quantitative traits. A Caballero, PD Keightley Genetics 138 (3), 883-900, 1994 | 150 | 1994 |
