| mRNA vaccines induce durable immune memory to SARS-CoV-2 and variants of concern RR Goel, MM Painter, SA Apostolidis, D Mathew, W Meng, AM Rosenfeld, ... Science 374 (6572), abm0829, 2021 | 709 | 2021 |
| Tumor cell-intrinsic factors underlie heterogeneity of immune cell infiltration and response to immunotherapy J Li, KT Byrne, F Yan, T Yamazoe, Z Chen, T Baslan, LP Richman, JH Lin, ... Immunity 49 (1), 178-193. e7, 2018 | 563 | 2018 |
| Induction of T-cell immunity overcomes complete resistance to PD-1 and CTLA-4 blockade and improves survival in pancreatic carcinoma R Winograd, KT Byrne, RA Evans, PM Odorizzi, ARL Meyer, DL Bajor, ... Cancer immunology research 3 (4), 399-411, 2015 | 461* | 2015 |
| Immunotherapy and prevention of pancreatic cancer AH Morrison, KT Byrne, RH Vonderheide Trends in cancer 4 (6), 418-428, 2018 | 356 | 2018 |
| Resident memory T cells in the skin mediate durable immunity to melanoma BT Malik, KT Byrne, JL Vella, P Zhang, TB Shabaneh, SM Steinberg, ... Science immunology 2 (10), eaam6346, 2017 | 255 | 2017 |
| CD40 stimulation obviates innate sensors and drives T cell immunity in cancer KT Byrne, RH Vonderheide Cell reports 15 (12), 2719-2732, 2016 | 238 | 2016 |
| CD40 agonistic monoclonal antibody APX005M (sotigalimab) and chemotherapy, with or without nivolumab, for the treatment of metastatic pancreatic adenocarcinoma: an open-label … MH O'Hara, EM O'Reilly, G Varadhachary, RA Wolff, ZA Wainberg, AH Ko, ... The lancet oncology 22 (1), 118-131, 2021 | 197 | 2021 |
| Deep immune profiling of MIS-C demonstrates marked but transient immune activation compared with adult and pediatric COVID-19 LA Vella, JR Giles, AE Baxter, DA Oldridge, C Diorio, L Kuri-Cervantes, ... Science immunology 6 (57), eabf7570, 2021 | 191 | 2021 |
| Lack of immunoediting in murine pancreatic cancer reversed with neoantigen RA Evans, MS Diamond, AJ Rech, T Chao, MW Richardson, JH Lin, ... JCI insight 1 (14), 2016 | 152 | 2016 |
| Sotigalimab and/or nivolumab with chemotherapy in first-line metastatic pancreatic cancer: clinical and immunologic analyses from the randomized phase 2 PRINCE trial LJ Padrón, DM Maurer, MH O’Hara, EM O’Reilly, RA Wolff, ZA Wainberg, ... Nature medicine 28 (6), 1167-1177, 2022 | 138 | 2022 |
| Tumor cell–intrinsic EPHA2 suppresses antitumor immunity by regulating PTGS2 (COX-2) N Markosyan, J Li, YH Sun, LP Richman, JH Lin, F Yan, L Quinones, ... The Journal of clinical investigation 129 (9), 3594-3609, 2019 | 136 | 2019 |
| IL-10 immunomodulation of myeloid cells regulates a murine model of ovarian cancer KM Hart, KT Byrne, MJ Molloy, EM Usherwood, B Berwin Frontiers in immunology 2, 29, 2011 | 126 | 2011 |
| Immune-mediated regression of established B16F10 melanoma by intratumoral injection of attenuated Toxoplasma gondii protects against rechallenge JR Baird, KT Byrne, PH Lizotte, S Toraya-Brown, UK Scarlett, ... The Journal of Immunology 190 (1), 469-478, 2013 | 116 | 2013 |
| Circulating CSF-1 promotes monocyte and macrophage phenotypes that enhance lupus nephritis J Menke, WA Rabacal, KT Byrne, Y Iwata, MM Schwartz, ER Stanley, ... Journal of the American Society of Nephrology 20 (12), 2581-2592, 2009 | 115 | 2009 |
| New perspectives on the role of vitiligo in immune responses to melanoma KT Byrne, MJ Turk Oncotarget 2 (9), 684, 2011 | 111 | 2011 |
| Neoadjuvant selicrelumab, an agonist CD40 antibody, induces changes in the tumor microenvironment in patients with resectable pancreatic cancer KT Byrne, CB Betts, R Mick, S Sivagnanam, DL Bajor, DA Laheru, ... Clinical Cancer Research 27 (16), 4574-4586, 2021 | 99 | 2021 |
| Synergistic immunotherapy of glioblastoma by dual targeting of IL-6 and CD40 F Yang, Z He, H Duan, D Zhang, J Li, H Yang, JF Dorsey, W Zou, ... Nature communications 12 (1), 3424, 2021 | 99 | 2021 |
| Tumor burden and immunotherapy: impact on immune infiltration and therapeutic outcomes SI Kim, CR Cassella, KT Byrne Frontiers in immunology 11, 629722, 2021 | 98 | 2021 |
| Sufficiency of CD40 activation and immune checkpoint blockade for T cell priming and tumor immunity AH Morrison, MS Diamond, CA Hay, KT Byrne, RH Vonderheide Proceedings of the National Academy of Sciences 117 (14), 8022-8031, 2020 | 96 | 2020 |
| UPenn COVID Processing Unit D Mathew, JR Giles, AE Baxter, DA Oldridge, AR Greenplate, JE Wu, ... Deep immune profiling of COVID-19 patients reveals distinct immunotypes with …, 2020 | 96 | 2020 |
