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Shaoxun Wang
Shaoxun Wang
Senior Scientist, Vertex Pharmaceuticals
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Year
Targeting vascular inflammation in ischemic stroke: Recent developments on novel immunomodulatory approaches
S Shekhar, MW Cunningham, MR Pabbidi, S Wang, GW Booz, F Fan
European journal of pharmacology 833, 531-544, 2018
1092018
Antidepressant-like effect of the ethanolic extract from Suanzaorenhehuan Formula in mice models of depression
J Liu, W Qiao, Y Yang, L Ren, Y Sun, S Wang
Journal of Ethnopharmacology 141 (1), 257-264, 2012
652012
Is beta-amyloid accumulation a cause or consequence of Alzheimer’s disease?
S Wang, PN Mims, RJ Roman, F Fan
Journal of Alzheimer's parkinsonism & dementia 1 (2), 2016
592016
Aging exacerbates impairments of cerebral blood flow autoregulation and cognition in diabetic rats
S Wang, W Lv, H Zhang, Y Liu, L Li, JR Jefferson, Y Guo, M Li, W Gao, ...
Geroscience 42, 1387-1410, 2020
472020
Accelerated cerebral vascular injury in diabetes is associated with vascular smooth muscle cell dysfunction
Y Guo, S Wang, Y Liu, L Fan, GW Booz, RJ Roman, Z Chen, F Fan
Geroscience 42, 547-561, 2020
462020
Novel mechanistic insights and potential therapeutic impact of TRPC6 in neurovascular coupling and ischemic stroke
S Shekhar, Y Liu, S Wang, H Zhang, X Fang, J Zhang, L Fan, B Zheng, ...
International journal of molecular sciences 22 (4), 2074, 2021
432021
Conflicting roles of 20-HETE in hypertension and renal end organ damage
C Zhang, GW Booz, Q Yu, X He, S Wang, F Fan
European journal of pharmacology 833, 190-200, 2018
422018
Reduced pericyte and tight junction coverage in old diabetic rats are associated with hyperglycemia-induced cerebrovascular pericyte dysfunction
Y Liu, H Zhang, S Wang, Y Guo, X Fang, B Zheng, W Gao, H Yu, Z Chen, ...
American Journal of Physiology-Heart and Circulatory Physiology 320 (2 …, 2021
402021
Enhanced renal ischemia-reperfusion injury in aging and diabetes
Y Muroya, X He, L Fan, S Wang, R Xu, F Fan, RJ Roman
American Journal of Physiology-Renal Physiology 315 (6), F1843-F1854, 2018
402018
Knockdown of Add3 impairs the myogenic response of renal afferent arterioles and middle cerebral arteries
F Fan, MR Pabbidi, Y Ge, L Li, S Wang, PN Mims, RJ Roman
American Journal of Physiology-Renal Physiology 312 (6), F971-F981, 2017
402017
Sex differences in the structure and function of rat middle cerebral arteries
S Wang, H Zhang, Y Liu, L Li, Y Guo, F Jiao, X Fang, JR Jefferson, M Li, ...
American Journal of Physiology-Heart and Circulatory Physiology 318 (5 …, 2020
392020
Impaired cerebral autoregulation-a common neurovascular pathway in diabetes may play a critical role in diabetes-related Alzheimer’s disease
S Shekhar, S Wang, PN Mims, E Gonzalez-Fernandez, C Zhang, X He, ...
Current research in diabetes & obesity journal 2 (3), 2017
322017
Influence of dual‐specificity protein phosphatase 5 on mechanical properties of rat cerebral and renal arterioles
H Zhang, C Zhang, Y Liu, W Gao, S Wang, X Fang, Y Guo, M Li, R Liu, ...
Physiological reports 8 (2), e14345, 2020
252020
A mutation in γ-adducin impairs autoregulation of renal blood flow and promotes the development of kidney disease
F Fan, AM Geurts, MR Pabbidi, Y Ge, C Zhang, S Wang, Y Liu, W Gao, ...
Journal of the American Society of Nephrology 31 (4), 687-700, 2020
242020
Recent insights into the protective mechanisms of paeoniflorin in neurological, cardiovascular, and renal diseases
F Jiao, K Varghese, S Wang, Y Liu, H Yu, GW Booz, RJ Roman, R Liu, ...
Journal of cardiovascular pharmacology 77 (6), 728-734, 2021
232021
Knockout of dual-specificity protein phosphatase 5 protects against hypertension-induced renal injury
C Zhang, X He, SR Murphy, H Zhang, S Wang, Y Ge, W Gao, JM Williams, ...
Journal of Pharmacology and Experimental Therapeutics 370 (2), 206-217, 2019
212019
Luseogliflozin, a sodium-glucose cotransporter-2 inhibitor, reverses cerebrovascular dysfunction and cognitive impairments in 18-mo-old diabetic animals
S Wang, F Jiao, JJ Border, X Fang, RF Crumpler, Y Liu, H Zhang, ...
American Journal of Physiology-Heart and Circulatory Physiology 322 (2 …, 2022
152022
Role of γ-adducin in actin cytoskeleton rearrangements in podocyte pathophysiology
W Gao, Y Liu, L Fan, B Zheng, JR Jefferson, S Wang, H Zhang, X Fang, ...
American Journal of Physiology-Renal Physiology 320 (1), F97-F113, 2021
142021
Vascular-cognitive impairment following high-thoracic spinal cord injury is associated with structural and functional maladaptations in cerebrovasculature
R Sachdeva, M Jia, S Wang, A Yung, MMZ Zheng, AHX Lee, A Monga, ...
Journal of neurotrauma 37 (18), 1963-1970, 2020
122020
Impact of impaired cerebral blood flow autoregulation on cognitive impairment
S Wang, C Tang, Y Liu, JJ Border, RJ Roman, F Fan
Frontiers in Aging 3, 1077302, 2022
102022
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