| Drug penetration in solid tumours AI Minchinton, IF Tannock Nature Reviews Cancer 6 (8), 583-592, 2006 | 3215 | 2006 |
| Targeting tumor hypoxia: suppression of breast tumor growth and metastasis by novel carbonic anhydrase IX inhibitors Y Lou, PC McDonald, A Oloumi, S Chia, C Ostlund, A Ahmadi, A Kyle, ... Cancer research 71 (9), 3364-3376, 2011 | 791 | 2011 |
| SHIP represses the generation of alternatively activated macrophages MJ Rauh, V Ho, C Pereira, A Sham, LM Sly, V Lam, L Huxham, ... Immunity 23 (4), 361-374, 2005 | 344 | 2005 |
| Translational activation of HIF1α by YB-1 promotes sarcoma metastasis AM El-Naggar, CJ Veinotte, H Cheng, TGP Grunewald, GL Negri, ... Cancer cell 27 (5), 682-697, 2015 | 333 | 2015 |
| Angiopoietin-2 functions as a Tie2 agonist in tumor models, where it limits the effects of VEGF inhibition C Daly, A Eichten, C Castanaro, E Pasnikowski, A Adler, AS Lalani, ... Cancer research 73 (1), 108-118, 2013 | 262 | 2013 |
| Limited tissue penetration of taxanes: a mechanism for resistance in solid tumors AH Kyle, LA Huxham, DM Yeoman, AI Minchinton Clinical Cancer Research 13 (9), 2804-2810, 2007 | 220 | 2007 |
| A low carbohydrate, high protein diet slows tumor growth and prevents cancer initiation VW Ho, K Leung, A Hsu, B Luk, J Lai, SY Shen, AI Minchinton, ... Cancer research 71 (13), 4484-4493, 2011 | 195 | 2011 |
| Notch initiates the endothelial-to-mesenchymal transition in the atrioventricular canal through autocrine activation of soluble guanylyl cyclase ACY Chang, YX Fu, VC Garside, K Niessen, L Chang, M Fuller, A Setiadi, ... Developmental cell 21 (2), 288-300, 2011 | 187 | 2011 |
| Targeting hypoxia-induced carbonic anhydrase IX enhances immune-checkpoint blockade locally and systemically SC Chafe, PC McDonald, S Saberi, O Nemirovsky, G Venkateswaran, ... Cancer immunology research 7 (7), 1064-1078, 2019 | 147 | 2019 |
| The prognostic impact of CD163-positive macrophages in follicular lymphoma: a study from the BC cancer agency and the lymphoma study association R Kridel, L Xerri, B Gelas-Dore, K Tan, P Feugier, A Vawda, D Canioni, ... Clinical Cancer Research 21 (15), 3428-3435, 2015 | 141 | 2015 |
| Direct visualization of heterogeneous extravascular distribution of trastuzumab in human epidermal growth factor receptor type 2 overexpressing xenografts JHE Baker, KE Lindquist, LA Huxham, AH Kyle, JT Sy, AI Minchinton Clinical Cancer Research 14 (7), 2171-2179, 2008 | 141 | 2008 |
| Characterization of three-dimensional tissue cultures using electrical impedance spectroscopy AH Kyle, CTO Chan, AI Minchinton Biophysical journal 76 (5), 2640-2648, 1999 | 132 | 1999 |
| The clinical testing of Ro 03-8799—pharmacokinetics, toxicology, tissue and tumor concentrations MI Saunders, PJ Anderson, MH Bennett, S Dische, A Minchinton, ... International Journal of Radiation Oncology* Biology* Physics 10 (9), 1759-1763, 1984 | 123 | 1984 |
| The effect of thalidomide on experimental tumors and metastases AI Minchinton, KH Fryer, KR Wendt, KA Clow, MMM Hayes Anti-Cancer Drugs 7 (3), 339-343, 1996 | 108 | 1996 |
| Suppression of VEGF secretion and changes in glioblastoma multiforme microenvironment by inhibition of integrin-linked kinase (ILK) LA Edwards, J Woo, LA Huxham, M Verreault, WH Dragowska, G Chiu, ... Molecular cancer therapeutics 7 (1), 59-70, 2008 | 106 | 2008 |
| Microregional effects of gemcitabine in HCT-116 xenografts LA Huxham, AH Kyle, JHE Baker, LK Nykilchuk, AI Minchinton Cancer research 64 (18), 6537-6541, 2004 | 102 | 2004 |
| Direct assessment of drug penetration into tissue using a novel application of three-dimensional cell culture AH Kyle, LA Huxham, ASJ Chiam, DH Sim, AI Minchinton Cancer research 64 (17), 6304-6309, 2004 | 97 | 2004 |
| Metronomic gemcitabine suppresses tumour growth, improves perfusion, and reduces hypoxia in human pancreatic ductal adenocarcinoma KKY Cham, JHE Baker, KS Takhar, JA Flexman, MQ Wong, DA Owen, ... British journal of cancer 103 (1), 52-60, 2010 | 95 | 2010 |
| Measurement of delivery and metabolism of tirapazamine to tumour tissue using the multilayered cell culture model AH Kyle, AI Minchinton Cancer chemotherapy and pharmacology 43, 213-220, 1999 | 95 | 1999 |
| Differentiation of vascular smooth muscle cells from local precursors during embryonic and adult arteriogenesis requires Notch signaling L Chang, M Noseda, M Higginson, M Ly, A Patenaude, M Fuller, AH Kyle, ... Proceedings of the National Academy of Sciences 109 (18), 6993-6998, 2012 | 91 | 2012 |
