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Claudia L. Kleinman
Claudia L. Kleinman
Verified email at mcgill.ca
Title
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Cited by
Year
Childhood cerebellar tumours mirror conserved fetal transcriptional programs
MC Vladoiu, I El-Hamamy, LK Donovan, H Farooq, BL Holgado, ...
Nature 572 (7767), 67-73, 2019
3542019
H3K27M induces defective chromatin spread of PRC2-mediated repressive H3K27me2/me3 and is essential for glioma tumorigenesis
AS Harutyunyan, B Krug, H Chen, S Papillon-Cavanagh, M Zeinieh, ...
Nature communications 10 (1), 1262, 2019
2572019
Comment on “Widespread RNA and DNA Sequence Differences in the Human Transcriptome”
CL Kleinman, J Majewski
Science 335, 1302-c, 2012
242*2012
H3. 3K27M cooperates with Trp53 loss and PDGFRA gain in mouse embryonic neural progenitor cells to induce invasive high-grade gliomas
M Pathania, N De Jay, N Maestro, AS Harutyunyan, J Nitarska, ...
Cancer cell 32 (5), 684-700. e9, 2017
2282017
Fusion of TTYH1 with the C19MC microRNA cluster drives expression of a brain-specific DNMT3B isoform in the embryonal brain tumor ETMR
CL Kleinman, N Gerges, S Papillon-Cavanagh, P Sin-Chan, ...
Nature genetics 46 (1), 39-44, 2014
2172014
Stalled developmental programs at the root of pediatric brain tumors
S Jessa, A Blanchet-Cohen, B Krug, M Vladoiu, M Coutelier, D Faury, ...
Nature genetics 51 (12), 1702-1713, 2019
1822019
Polyadenylation-dependent control of long noncoding RNA expression by the poly (A)-binding protein nuclear 1
YB Beaulieu, CL Kleinman, AM Landry-Voyer, J Majewski, F Bachand
PLoS genetics 8 (11), e1003078, 2012
1742012
Pervasive H3K27 acetylation leads to ERV expression and a therapeutic vulnerability in H3K27M gliomas
B Krug, N De Jay, AS Harutyunyan, S Deshmukh, DM Marchione, ...
Cancer cell 35 (5), 782-797. e8, 2019
1722019
RNA sequencing reveals the role of splicing polymorphisms in regulating human gene expression
E Lalonde, KCH Ha, Z Wang, A Bemmo, CL Kleinman, T Kwan, ...
Genome research 21 (4), 545-554, 2011
1522011
Macrocyclic lactone resistance in Dirofilaria immitis: failure of heartworm preventives and investigation of genetic markers for resistance
C Bourguinat, ACY Lee, R Lizundia, BL Blagburn, JL Liotta, MS Kraus, ...
Veterinary parasitology 210 (3-4), 167-178, 2015
1412015
A pseudouridine synthase module is essential for mitochondrial protein synthesis and cell viability
H Antonicka, K Choquet, ZY Lin, AC Gingras, CL Kleinman, ...
EMBO reports 18 (1), 28-38, 2017
1392017
Histone H3. 3G34-mutant interneuron progenitors co-opt PDGFRA for gliomagenesis
CCL Chen, S Deshmukh, S Jessa, D Hadjadj, V Lisi, AF Andrade, D Faury, ...
Cell 183 (6), 1617-1633. e22, 2020
1112020
A C19MC-LIN28A-MYCN oncogenic circuit driven by hijacked super-enhancers is a distinct therapeutic vulnerability in ETMRs: a lethal brain tumor
P Sin-Chan, I Mumal, T Suwal, B Ho, X Fan, I Singh, Y Du, M Lu, N Patel, ...
Cancer cell 36 (1), 51-67. e7, 2019
822019
Dual targeting of polyamine synthesis and uptake in diffuse intrinsic pontine gliomas
A Khan, LD Gamble, DH Upton, C Ung, DMT Yu, A Ehteda, R Pandher, ...
Nature communications 12 (1), 971, 2021
772021
A targetable EGFR-dependent tumor-initiating program in breast cancer
P Savage, A Blanchet-Cohen, T Revil, D Badescu, SMI Saleh, YC Wang, ...
Cell reports 21 (5), 1140-1149, 2017
762017
PRMT5 is essential for B cell development and germinal center dynamics
LC Litzler, A Zahn, AP Meli, S Hébert, AM Patenaude, SP Methot, ...
Nature communications 10 (1), 22, 2019
722019
TRPV4 and KRAS and FGFR1 gain-of-function mutations drive giant cell lesions of the jaw
CC Gomes, T Gayden, A Bajic, OF Harraz, J Pratt, H Nikbakht, E Bareke, ...
Nature communications 9 (1), 4572, 2018
722018
Failure of human rhombic lip differentiation underlies medulloblastoma formation
LD Hendrikse, P Haldipur, O Saulnier, J Millman, AH Sjoboen, ...
Nature 609 (7929), 1021-1028, 2022
662022
SWI/SNF-compromised cancers are susceptible to bromodomain inhibitors
T Shorstova, M Marques, J Su, J Johnston, CL Kleinman, N Hamel, ...
Cancer research 79 (10), 2761-2774, 2019
642019
Computational methods for evaluating phylogenetic models of coding sequence evolution with dependence between codons
N Rodrigue, CL Kleinman, H Philippe, N Lartillot
Molecular Biology and Evolution 26 (7), 1663-1676, 2009
612009
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