Christine Doucette
Christine Doucette
Associate Professor, University of Manitoba
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Transgenic plant cells lacking mitochondrial alternative oxidase have increased susceptibility to mitochondria-dependent and-independent pathways of programmed cell death
CA Robson, GC Vanlerberghe
Plant physiology 129 (4), 1908-1920, 2002
Induction of mitochondrial alternative oxidase in response to a cell signal pathway down-regulating the cytochrome pathway prevents programmed cell death
GC Vanlerberghe, CA Robson, JYH Yip
Plant physiology 129 (4), 1829-1842, 2002
The role of alternative oxidase in modulating carbon use efficiency and growth during macronutrient stress in tobacco cells
SM Sieger, BK Kristensen, CA Robson, S Amirsadeghi, EWY Eng, ...
Journal of Experimental Botany 56 (416), 1499-1515, 2005
Maternal obesity, diabetes during pregnancy and epigenetic mechanisms that influence the developmental origins of cardiometabolic disease in the offspring
P Agarwal, TS Morriseau, SM Kereliuk, CA Doucette, BA Wicklow, ...
Critical reviews in clinical laboratory sciences 55 (2), 71-101, 2018
The role of the mitochondrion in plant responses to biotic stress
S Amirsadeghi, CA Robson, GC Vanlerberghe
Physiologia plantarum 129 (1), 253-266, 2007
β-cell uncoupling protein 2 regulates reactive oxygen species production, which influences both insulin and glucagon secretion
CA Robson-Doucette, S Sultan, EM Allister, JD Wikstrom, V Koshkin, ...
Diabetes 60 (11), 2710-2719, 2011
Changes in plant mitochondrial electron transport alter cellular levels of reactive oxygen species and susceptibility to cell death signaling molecules
S Amirsadeghi, CA Robson, AE McDonald, GC Vanlerberghe
Plant and Cell Physiology 47 (11), 1509-1519, 2006
Glucose-induced beta cell dysfunction in vivo in rats: link between oxidative stress and endoplasmic reticulum stress
C Tang, K Koulajian, I Schuiki, L Zhang, T Desai, A Ivovic, P Wang, ...
Diabetologia 55, 1366-1379, 2012
Maternal obesity characterized by gestational diabetes increases the susceptibility of rat offspring to hepatic steatosis via a disrupted liver metabolome
TJ Pereira, MA Fonseca, KE Campbell, BL Moyce, LK Cole, GM Hatch, ...
The Journal of physiology 593 (14), 3181-3197, 2015
Limited mitochondrial permeabilization is an early manifestation of palmitate-induced lipotoxicity in pancreatic β-cells
V Koshkin, FF Dai, CA Robson-Doucette, CB Chan, MB Wheeler
Journal of Biological Chemistry 283 (12), 7936-7948, 2008
UCP2 regulates the glucagon response to fasting and starvation
EM Allister, CA Robson-Doucette, KJ Prentice, AB Hardy, S Sultan, ...
Diabetes 62 (5), 1623-1633, 2013
Uncoupling protein 2 regulates reactive oxygen species formation in islets and influences susceptibility to diabetogenic action of streptozotocin
SC Lee, CA Robson-Doucette, MB Wheeler
Journal of Endocrinology 203 (1), 33, 2009
Glutathionylation state of uncoupling protein-2 and the control of glucose-stimulated insulin secretion
RJ Mailloux, A Fu, C Robson-Doucette, EM Allister, MB Wheeler, ...
Journal of biological chemistry 287 (47), 39673-39685, 2012
Insulin mimetics in Urtica dioica: structural and computational analyses of Urtica dioica extracts
MS Domola, V Vu, CA Robson‐Doucette, G Sweeney, MB Wheeler
Phytotherapy research 24 (S2), S175-S182, 2010
Bcl-2 regulates reactive oxygen species signaling and a redox-sensitive mitochondrial proton leak in mouse pancreatic β-cells
M Aharoni-Simon, R Shumiatcher, A Yeung, AZL Shih, VW Dolinsky, ...
Endocrinology 157 (6), 2270-2281, 2016
Maternal resveratrol administration protects against gestational diabetes‐induced glucose intolerance and islet dysfunction in the rat offspring
GM Brawerman, SM Kereliuk, N Brar, LK Cole, N Seshadri, TJ Pereira, ...
The Journal of Physiology 597 (16), 4175-4192, 2019
Uncoupling protein 2 regulates daily rhythms of insulin secretion capacity in MIN6 cells and isolated islets from male mice
N Seshadri, ME Jonasson, KL Hunt, B Xiang, S Cooper, MB Wheeler, ...
Molecular metabolism 6 (7), 760-769, 2017
Gestational diabetes adversely affects pancreatic islet architecture and function in the male rat offspring
P Agarwal, N Brar, TS Morriseau, SM Kereliuk, MA Fonseca, LK Cole, ...
Endocrinology 160 (8), 1907-1925, 2019
Mitochondrial respiration correlates with prognostic markers in chronic lymphocytic leukemia and is normalized by ibrutinib treatment
S Roy Chowdhury, EDJ Bouchard, R Saleh, Z Nugent, C Peltier, E Mejia, ...
Cancers 12 (3), 650, 2020
In utero exposure to gestational diabetes mellitus conditions TLR4 and TLR2 activated IL-1beta responses in spleen cells from rat offspring
Q Li, TJ Pereira, BL Moyce, TH Mahood, CA Doucette, J Rempel, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1862 (11 …, 2016
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