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Xi Lei
Xi Lei
Research Technician, St. Michael's Hospital
Verified email at smh.ca
Title
Cited by
Cited by
Year
Platelets and platelet adhesion molecules: novel mechanisms of thrombosis and anti-thrombotic therapies
XR Xu, N Carrim, MAD Neves, T McKeown, TW Stratton, RMP Coelho, ...
Thrombosis journal 14, 37-46, 2016
1882016
Anfibatide, a novel GPIb complex antagonist, inhibits platelet adhesion and thrombus formation in vitro and in vivo in murine models of thrombosis
X Lei, A Reheman, Y Hou, H Zhou, Y Wang, AH Marshall, C Liang, X Dai, ...
Thrombosis and haemostasis 112 (02), 279-289, 2014
1422014
Glucagon-like peptide 1 receptor activation attenuates platelet aggregation and thrombosis
A Cameron-Vendrig, A Reheman, MA Siraj, XR Xu, Y Wang, X Lei, ...
Diabetes 65 (6), 1714-1723, 2016
1062016
Apolipoprotein A-IV binds αIIbβ3 integrin and inhibits thrombosis
XR Xu, Y Wang, R Adili, L Ju, CM Spring, JW Jin, H Yang, MAD Neves, ...
Nature communications 9 (1), 3608, 2018
902018
The role of endothelial cell adhesion molecules P‐selectin, E‐selectin and intercellular adhesion molecule‐1 in leucocyte recruitment induced by exogenous methylglyoxal
Y Su, X Lei, L Wu, L Liu
Immunology 137 (1), 65-79, 2012
742012
The integrin PSI domain has an endogenous thiol isomerase function and is a novel target for antiplatelet therapy
G Zhu, Q Zhang, EC Reddy, N Carrim, Y Chen, XR Xu, M Xu, Y Wang, ...
Blood, The Journal of the American Society of Hematology 129 (13), 1840-1854, 2017
662017
Tracking neutrophil intraluminal crawling, transendothelial migration and chemotaxis in tissue by intravital video microscopy
N Xu, X Lei, L Liu
JoVE (Journal of Visualized Experiments), e3296, 2011
362011
Endothelial-specific deletion of autophagy-related 7 (ATG7) attenuates arterial thrombosis in mice
JW Yau, KK Singh, Y Hou, X Lei, A Ramadan, A Quan, H Teoh, ...
The Journal of Thoracic and Cardiovascular Surgery 154 (3), 978-988. e1, 2017
302017
In vitro assessment and phase I randomized clinical trial of anfibatide a snake venom derived anti-thrombotic agent targeting human platelet GPIbα
BX Li, X Dai, XR Xu, R Adili, MAD Neves, X Lei, C Shen, G Zhu, Y Wang, ...
Scientific reports 11 (1), 11663, 2021
282021
Different microvascular permeability responses elicited by the CXC chemokines MIP-2 and KC during leukocyte recruitment: role of LSP1
X Lei, M Hossain, SM Qadri, L Liu
Biochemical and biophysical research communications 423 (3), 484-489, 2012
282012
The first in vitro and in vivo assessment of anfibatide, a novel glycoprotein Ib antagonist, in mice and in a phase I human clinical trial
Y Hou, X Lei, BX Li, X Dai, Z Yang, F Qian, G Zhang, Z Xu, J Liu, C Liang, ...
Blood 122 (21), 577, 2013
142013
Novel contact–kinin inhibitor sylvestin targets thromboinflammation and ameliorates ischemic stroke
Z Zhang, C Shen, M Fang, Y Han, C Long, W Liu, M Yang, M Liu, D Zhang, ...
Cellular and Molecular Life Sciences 79 (5), 240, 2022
132022
The fibrinogen but not the F actor VIII content of transfused plasma determines its effectiveness at reducing bleeding in coagulopathic mice
LJ Eltringham‐Smith, X Lei, A Reheman, MD Lambourne, EL Pryzdial, ...
Transfusion 55 (5), 1040-1050, 2015
102015
Control of data variations in intravital microscopy thrombosis models
X Lei, DT MacKeigan, H Ni
Journal of Thrombosis and Haemostasis 18 (11), 2823-2825, 2020
52020
SARS-CoV-2 RBD and its variants can induce platelet activation and clearance: Implications for antibody therapy and vaccinations against COVID-19
X Ma, J Liang, G Zhu, P Bhoria, AA Shoara, DT MacKeigan, CJ Khoury, ...
Research 6, 0124, 2023
42023
Apolipoprotein Α-IV is a novel ligand of platelet αIIbβ3 integrin and an endogenous thrombosis inhibitor: measurement of single-molecular interactions by biomembrane force probe
X Xu, CM Spring, L Ju, Y Wang, A Reheman, H Yang, JW Jin, X Lei, ...
Blood 124 (21), 92, 2014
32014
Development of a novel antithrombotic therapy targeting platelet GPIbα: assessment of anfibatide in vitro and in phase I clinical trial
Y Hou, A Reheman, BX Li, X Dai, Z Yang, F Qian, G Zhang, Z Xu, J Liu, ...
Arteriosclerosis, Thrombosis, and Vascular Biology 34 (suppl_1), A499-A499, 2014
32014
Dual roles of fucoidan-GPIbα interaction in thrombosis and hemostasis: implications for drug development targeting GPIbα
C Shen, DT Mackeigan, AA Shoara, R Xu, P Bhoria, D Karakas, W Ma, ...
Journal of Thrombosis and Haemostasis 21 (5), 1274-1288, 2023
22023
Integrin PSI domain has endogenous thiol isomerase function and is a novel target for anti-thrombotic therapy
N Carrim, G Zhu, EC Reddy, M Xu, X Xu, Y Wang, Y Hou, L Ma, C Lavalle, ...
JOURNAL OF THROMBOSIS AND HAEMOSTASIS 13, 60-61, 2015
22015
Two Birds One Stone: Salvianolic Acid B Inhibits Coagulation And Platelet Aggregation
M Neves, Y Wang, T Ni, X Lei, TW Stratton, S Yu, RC Gallant, D Zhang, ...
Circulation 140 (Suppl_1), A17159-A17159, 2019
12019
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