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Leeat Keren
Leeat Keren
Verified email at weizmann.ac.il - Homepage
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Cited by
Year
A structured tumor-immune microenvironment in triple negative breast cancer revealed by multiplexed ion beam imaging
L Keren, M Bosse, D Marquez, R Angoshtari, S Jain, S Varma, SR Yang, ...
Cell 174 (6), 1373-1387. e19, 2018
7942018
Inferring gene regulatory logic from high-throughput measurements of thousands of systematically designed promoters
E Sharon, Y Kalma, A Sharp, T Raveh-Sadka, M Levo, D Zeevi, L Keren, ...
Nature biotechnology 30 (6), 521-530, 2012
5442012
Self-targeting by CRISPR: gene regulation or autoimmunity?
A Stern, L Keren, O Wurtzel, G Amitai, R Sorek
Trends in genetics 26 (8), 335-340, 2010
4672010
Whole-cell segmentation of tissue images with human-level performance using large-scale data annotation and deep learning
NF Greenwald, G Miller, E Moen, A Kong, A Kagel, T Dougherty, ...
Nature biotechnology 40 (4), 555-565, 2022
4042022
MIBI-TOF: A multiplexed imaging platform relates cellular phenotypes and tissue structure
L Keren, M Bosse, S Thompson, T Risom, K Vijayaragavan, E McCaffrey, ...
Science advances 5 (10), eaax5851, 2019
2662019
Manipulating nucleosome disfavoring sequences allows fine-tune regulation of gene expression in yeast
T Raveh-Sadka, M Levo, U Shabi, B Shany, L Keren, M Lotan-Pompan, ...
Nature genetics 44 (7), 743-750, 2012
2502012
Promoters maintain their relative activity levels under different growth conditions
L Keren, O Zackay, M Lotan‐Pompan, U Barenholz, E Dekel, V Sasson, ...
Molecular systems biology 9 (1), 701, 2013
2132013
Transition to invasive breast cancer is associated with progressive changes in the structure and composition of tumor stroma
T Risom, DR Glass, I Averbukh, CC Liu, A Baranski, A Kagel, ...
Cell 185 (2), 299-310. e18, 2022
1922022
Massively parallel interrogation of the effects of gene expression levels on fitness
L Keren, J Hausser, M Lotan-Pompan, IV Slutskin, H Alisar, S Kaminski, ...
Cell 166 (5), 1282-1294. e18, 2016
1872016
Central dogma rates and the trade-off between precision and economy in gene expression
J Hausser, A Mayo, L Keren, U Alon
Nature communications 10 (1), 68, 2019
1662019
Probing the effect of promoters on noise in gene expression using thousands of designed sequences
E Sharon, D van Dijk, Y Kalma, L Keren, O Manor, Z Yakhini, E Segal
Genome research 24 (10), 1698-1706, 2014
1262014
The immunoregulatory landscape of human tuberculosis granulomas
EF McCaffrey, M Donato, L Keren, Z Chen, A Delmastro, MB Fitzpatrick, ...
Nature immunology 23 (2), 318-329, 2022
1222022
Sequence features of yeast and human core promoters that are predictive of maximal promoter activity
S Lubliner, L Keren, E Segal
Nucleic acids research 41 (11), 5569-5581, 2013
1112013
Noise in gene expression is coupled to growth rate
L Keren, D Van Dijk, S Weingarten-Gabbay, D Davidi, G Jona, ...
Genome research 25 (12), 1893-1902, 2015
912015
Tumor heterogeneity
D Pe’er, S Ogawa, O Elhanani, L Keren, TG Oliver, D Wedge
Cancer cell 39 (8), 1015-1017, 2021
682021
Compensation for differences in gene copy number among yeast ribosomal proteins is encoded within their promoters
D Zeevi, E Sharon, M Lotan-Pompan, Y Lubling, Z Shipony, ...
Genome research 21 (12), 2114-2128, 2011
632011
Spatial profiling technologies illuminate the tumor microenvironment
O Elhanani, R Ben-Uri, L Keren
Cancer Cell 41 (3), 404-420, 2023
552023
Modeling Multiplexed Images with Spatial-LDA Reveals Novel Tissue Microenvironments
Z Chen, I Soifer, H Hilton, L Keren, V Jojic
Journal of Computational Biology 27 (8), 1204-1218, 2020
472020
Adjacent cell marker lateral spillover compensation and reinforcement for multiplexed images
Y Bai, B Zhu, X Rovira-Clave, H Chen, M Markovic, CN Chan, TH Su, ...
Frontiers in immunology 12, 652631, 2021
332021
Multiplexed imaging analysis of the tumor-immune microenvironment reveals predictors of outcome in triple-negative breast cancer
A Patwa, R Yamashita, J Long, T Risom, M Angelo, L Keren, DL Rubin
Communications Biology 4 (1), 852, 2021
312021
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