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Fuguo Jiang, Ph.D.
Fuguo Jiang, Ph.D.
Assistant Professor, Department of Cancer Biology, UT MD Anderson Cancer Center
Verified email at mdanderson.org - Homepage
Title
Cited by
Cited by
Year
CRISPR–Cas9 structures and mechanisms
F Jiang, JA Doudna
Annual review of biophysics 46, 505-529, 2017
19652017
Structures of Cas9 endonucleases reveal RNA-mediated conformational activation
M Jinek, F Jiang, DW Taylor, SH Sternberg, E Kaya, E Ma, C Anders, ...
Science 343 (6176), 1247997, 2014
14912014
Innate immunity induced by composition-dependent RIG-I recognition of hepatitis C virus RNA
T Saito, DM Owen, F Jiang, J Marcotrigiano, M Gale Jr
Nature 454 (7203), 523-527, 2008
9152008
Nanoparticle delivery of Cas9 ribonucleoprotein and donor DNA in vivo induces homology-directed DNA repair
K Lee, M Conboy, HM Park, F Jiang, HJ Kim, MA Dewitt, VA Mackley, ...
Nature biomedical engineering 1 (11), 889-901, 2017
6952017
Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage
F Jiang, DW Taylor, JS Chen, JE Kornfeld, K Zhou, AJ Thompson, ...
Science 351 (6275), 867-871, 2016
6582016
A Cas9–guide RNA complex preorganized for target DNA recognition
F Jiang, K Zhou, L Ma, S Gressel, JA Doudna
Science 348 (6242), 1477-1481, 2015
6052015
Structural basis of RNA recognition and activation by innate immune receptor RIG-I
F Jiang, A Ramanathan, MT Miller, GQ Tang, M Gale, SS Patel, ...
Nature 479 (7373), 423-427, 2011
4852011
Disabling Cas9 by an anti-CRISPR DNA mimic
JS Fuguo Jiang, Jun-Jie Liu, Nicolas L. Bray, Benjamin J. Rauch, Seung Hyun ...
Science Advances 3 (no. 7, e1701620), DOI: 10.1126/sciadv.1701620, 2017
354*2017
Structural basis for m7G recognition and 2′-O-methyl discrimination in capped RNAs by the innate immune receptor RIG-I
SC Devarkar, C Wang, MT Miller, A Ramanathan, F Jiang, AG Khan, ...
Proceedings of the National Academy of Sciences 113 (3), 596-601, 2016
3052016
The structural biology of CRISPR-Cas systems
F Jiang, JA Doudna
Current opinion in structural biology 30, 100-111, 2015
2322015
Nucleosome breathing and remodeling constrain CRISPR-Cas9 function
RS Isaac, F Jiang, JA Doudna, WA Lim, GJ Narlikar, R Almeida
Elife 5, e13450, 2016
2282016
Protective humoral responses to severe acute respiratory syndrome-associated coronavirus: implications for the design of an effective protein-based vaccine
H Pang, Y Liu, X Han, Y Xu, F Jiang, D Wu, X Kong, M Bartlam, Z Rao
Journal of general virology 85 (10), 3109-3113, 2004
1022004
Extension of the crRNA enhances Cpf1 gene editing in vitro and in vivo
HM Park, H Liu, J Wu, A Chong, V Mackley, C Fellmann, A Rao, F Jiang, ...
Nature communications 9 (1), 3313, 2018
862018
Temperature-responsive competitive inhibition of CRISPR-Cas9
F Jiang, JJ Liu, BA Osuna, M Xu, JD Berry, BJ Rauch, E Nogales, ...
Molecular cell 73 (3), 601-610. e5, 2019
762019
Structure of human spindlin1: tandem Tudor-like domains for cell cycle regulation
Q Zhao, L Qin, F Jiang, B Wu, W Yue, F Xu, Z Rong, H Yuan, X Xie, Y Gao, ...
Journal of biological chemistry 282 (1), 647-656, 2007
672007
Regulation of retinoic acid inducible Gene-I (RIG-I) activation by the histone deacetylase 6
HM Liu, F Jiang, YM Loo, SZ Hsu, TY Hsiang, J Marcotrigiano, M Gale
EBioMedicine, 2016
632016
Cas9 crystals and methods of use thereof
JA Doudna, SH Sternberg, M Jinek, F Jiang, E Kaya, DW Taylor Jr
US Patent 9,963,689, 2018
392018
The autoinhibitory CARD2-Hel2i Interface of RIG-I governs RNA selection
A Ramanathan, SC Devarkar, F Jiang, MT Miller, AG Khan, ...
Nucleic acids research 44 (2), 896-909, 2016
382016
Expression, purification, crystallization and preliminary X-ray analysis of human spindlin1, an ovarian cancer-related protein
F Jiang, Q Zhao, L Qin, H Pang, X Pei, Z Rao
Protein and peptide letters 13 (2), 203-205, 2006
152006
Rapid genotypic antibiotic susceptibility test using CRISPR-Cas12a for urinary tract infection
J Chen, F Jiang, CW Huang, L Lin
Analyst 145 (15), 5226-5231, 2020
132020
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