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Tianyuan Lu
Tianyuan Lu
University of Toronto
Verified email at mail.mcgill.ca - Homepage
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Cited by
Year
Genomic atlas of the plasma metabolome prioritizes metabolites implicated in human diseases
Y Chen, T Lu, U Pettersson-Kymmer, ID Stewart, G Butler-Laporte, ...
Nature Genetics 55 (1), 44-53, 2023
772023
H3K27M in Gliomas Causes a One-Step Decrease in H3K27 Methylation and Reduced Spreading within the Constraints of H3K36 Methylation
AS Harutyunyan*, H Chen*, T Lu, C Horth, H Nikbakht, B Krug, C Russo, ...
Cell Reports 33 (7), 108390, 2020
572020
Individuals with common diseases but with a low polygenic risk score could be prioritized for rare variant screening
T Lu, S Zhou, H Wu, V Forgetta, CMT Greenwood, JB Richards
Genetics in Medicine 23 (3), 508-515, 2021
462021
Reshuffling of the ancestral core-eudicot genome shaped chromatin topology and epigenetic modification in Panax
ZH Wang, XF Wang, T Lu, MR Li, P Jiang, J Zhao, ST Liu, XQ Fu, ...
Nature Communications 13 (1), 1902, 2022
412022
Improved prediction of fracture risk leveraging a genome-wide polygenic risk score
T Lu*, V Forgetta*, J Keller-Baruch, M Nethander, D Bennett, M Forest, ...
Genome Medicine 13 (1), 1-15, 2021
402021
Polygenic risk for coronary heart disease acts through atherosclerosis in type 2 diabetes
T Lu, V Forgetta, OHY Yu, L Mokry, M Gregory, G Thanassoulis, ...
Cardiovascular Diabetology 19, 1-10, 2020
312020
Proteome-wide Mendelian randomization implicates nephronectin as an actionable mediator of the effect of obesity on COVID-19 severity
S Yoshiji, G Butler-Laporte, T Lu, JDS Willett, CY Su, T Nakanishi, ...
Nature Metabolism 5 (2), 248-264, 2023
242023
Investigating transcriptome-wide sex dimorphism by multi-level analysis of single-cell RNA sequencing data in ten mouse cell types
T Lu, JC Mar
Biology of sex Differences 11, 1-20, 2020
242020
A Polygenic Risk Score to Predict Future Adult Short Stature Among Children
T Lu, V Forgetta, H Wu, JRB Perry, KK Ong, CMT Greenwood, ...
The Journal of Clinical Endocrinology & Metabolism 106 (7), 1918-1928, 2021
202021
Transcriptional reprogramming of skeletal muscle stem cells by the niche environment
F Lazure*, R Farouni*, K Sahinyan, DM Blackburn, ...
Nature Communications 14 (1), 535, 2023
172023
Polygenic risk score as a possible tool for identifying familial monogenic causes of complex diseases
T Lu, V Forgetta, JB Richards, CMT Greenwood
Genetics in Medicine 24 (7), 1545-1555, 2022
162022
eXclusionarY: 10 years later, where are the sex chromosomes in GWASs?
L Sun, Z Wang, T Lu, TA Manolio, AD Paterson
The American Journal of Human Genetics 110 (6), 903-912, 2023
142023
Circulating Proteins Influencing Psychiatric Disease: A Mendelian Randomization Study
T Lu, V Forgetta, CMT Greenwood, S Zhou, JB Richards
Biological Psychiatry 93 (1), 82-91, 2023
122023
Whole-genome bisulfite sequencing in systemic sclerosis provides novel targets to understand disease pathogenesis
T Lu, KO Klein, I Colmegna, M Lora, CMT Greenwood, M Hudson
BMC medical genomics 12, 1-12, 2019
112019
Simultaneous SNP selection and adjustment for population structure in high dimensional prediction models
SR Bhatnagar, Y Yang, T Lu, E Schurr, JC Loredo-Osti, M Forest, ...
PLoS genetics 16 (5), e1008766, 2020
102020
Rapid Divergence Followed by Adaptation to Contrasting Ecological Niches of Two Closely Related Columbine Species Aquilegia japonica and A. oxysepala
MR Li, HY Wang, N Ding, T Lu, YC Huang, HX Xiao, B Liu, LF Li
Genome biology and evolution 11 (3), 919-930, 2019
102019
Pan-cancer analysis of mRNA stability for decoding tumour post-transcriptional programs
G Perron, P Jandaghi, E Moslemi, T Nishimura, M Rajaee, R Alkallas, ...
Communications Biology 5, 851, 2022
92022
A Sparse Additive Model for High-Dimensional Interactions with an Exposure Variable
SR Bhatnagar, T Lu, A Lovato, DL Olds, MS Kobor, MJ Meaney, ...
Computational Statistics & Data Analysis, 107624, 2022
82022
Capturing additional genetic risk from family history for improved polygenic risk prediction
T Lu, V Forgetta, JB Richards, CMT Greenwood
Communications Biology 5 (1), 595, 2022
72022
Causal associations between body fat accumulation and COVID-19 severity: A Mendelian randomization study
S Yoshiji, D Tanaka, M Hiroto, T Lu, G Butler-Laporte, T Murakami, ...
Frontiers in Endocrinology 13, 899625, 2022
62022
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