| The BioPlex network: a systematic exploration of the human interactome EL Huttlin, L Ting, RJ Bruckner, F Gebreab, MP Gygi, J Szpyt, S Tam, ... Cell 162 (2), 425-440, 2015 | 1408 | 2015 |
| Architecture of the human interactome defines protein communities and disease networks EL Huttlin, RJ Bruckner, JA Paulo, JR Cannon, L Ting, K Baltier, G Colby, ... Nature 545 (7655), 505-509, 2017 | 1354 | 2017 |
| Deletion of the developmentally essential gene ATR in adult mice leads to age-related phenotypes and stem cell loss Y Ruzankina, C Pinzon-Guzman, A Asare, T Ong, L Pontano, G Cotsarelis, ... Cell stem cell 1 (1), 113-126, 2007 | 802 | 2007 |
| Dual proteome-scale networks reveal cell-specific remodeling of the human interactome EL Huttlin, RJ Bruckner, J Navarrete-Perea, JR Cannon, K Baltier, ... Cell 184 (11), 3022-3040. e28, 2021 | 560 | 2021 |
| Excessive cell growth causes cytoplasm dilution and contributes to senescence GE Neurohr, RL Terry, J Lengefeld, M Bonney, GP Brittingham, F Moretto, ... cell 176 (5), 1083-1097. e18, 2019 | 401 | 2019 |
| Ferritinophagy via NCOA4 is required for erythropoiesis and is regulated by iron dependent HERC2-mediated proteolysis JD Mancias, L Pontano Vaites, S Nissim, DE Biancur, AJ Kim, X Wang, ... elife 4, e10308, 2015 | 365 | 2015 |
| TMTpro reagents: a set of isobaric labeling mass tags enables simultaneous proteome-wide measurements across 16 samples J Li, JG Van Vranken, L Pontano Vaites, DK Schweppe, EL Huttlin, ... Nature methods 17 (4), 399-404, 2020 | 342 | 2020 |
| Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase P Aggarwal, LP Vaites, JK Kim, H Mellert, B Gurung, H Nakagawa, ... Cancer cell 18 (4), 329-340, 2010 | 260 | 2010 |
| A quantitative tissue-specific landscape of protein redox regulation during aging H Xiao, MP Jedrychowski, DK Schweppe, EL Huttlin, Q Yu, DE Heppner, ... Cell 180 (5), 968-983. e24, 2020 | 259 | 2020 |
| Probing the global cellular responses to lipotoxicity caused by saturated fatty acids M Piccolis, LM Bond, M Kampmann, P Pulimeno, C Chitraju, CBK Jayson, ... Molecular cell 74 (1), 32-44. e8, 2019 | 204 | 2019 |
| A systematic analysis of factors localized to damaged chromatin reveals PARP-dependent recruitment of transcription factors L Izhar, B Adamson, A Ciccia, J Lewis, L Pontano-Vaites, Y Leng, ... Cell reports 11 (9), 1486-1500, 2015 | 170 | 2015 |
| Nuclear accumulation of cyclin D1 during S phase inhibits Cul4-dependent Cdt1 proteolysis and triggers p53-dependent DNA rereplication P Aggarwal, MD Lessie, DI Lin, L Pontano, AB Gladden, B Nuskey, ... Genes & development 21 (22), 2908-2922, 2007 | 140 | 2007 |
| PERK utilizes intrinsic lipid kinase activity to generate phosphatidic acid, mediate Akt activation, and promote adipocyte differentiation E Bobrovnikova-Marjon, D Pytel, MJ Riese, LP Vaites, N Singh, ... Molecular and cellular biology 32 (12), 2268-2278, 2012 | 124 | 2012 |
| Systematic analysis of human cells lacking ATG8 proteins uncovers roles for GABARAPs and the CCZ1/MON1 regulator C18orf8/RMC1 in macroautophagic and selective autophagic flux LP Vaites, JA Paulo, EL Huttlin, JW Harper Molecular and cellular biology, 2018 | 109 | 2018 |
| Protein aggregation mediates stoichiometry of protein complexes in aneuploid cells CM Brennan, LP Vaites, JN Wells, S Santaguida, JA Paulo, Z Storchova, ... Genes & development 33 (15-16), 1031-1047, 2019 | 93 | 2019 |
| The Fbx4 tumor suppressor regulates cyclin D1 accumulation and prevents neoplastic transformation LP Vaites, EK Lee, Z Lian, O Barbash, D Roy, M Wasik, AJP Klein-Szanto, ... Molecular and cellular biology 31 (22), 4513-4523, 2011 | 79 | 2011 |
| Genotoxic stress-induced cyclin D1 phosphorylation and proteolysis are required for genomic stability LL Pontano, P Aggarwal, O Barbash, EJ Brown, CH Bassing, JA Diehl Molecular and cellular biology 28 (23), 7245-7258, 2008 | 73 | 2008 |
| Proteome-wide mapping of short-lived proteins in human cells J Li, Z Cai, LP Vaites, N Shen, DC Mitchell, EL Huttlin, JA Paulo, BL Harry, ... Molecular cell 81 (22), 4722-4735. e5, 2021 | 71 | 2021 |
| Hook3 is a scaffold for the opposite-polarity microtubule-based motors cytoplasmic dynein-1 and KIF1C AA Kendrick, AM Dickey, WB Redwine, PT Tran, LP Vaites, ... Journal of Cell Biology 218 (9), 2982-3001, 2019 | 69 | 2019 |
| A multi-scale map of cell structure fusing protein images and interactions Y Qin, EL Huttlin, CF Winsnes, ML Gosztyla, L Wacheul, MR Kelly, ... Nature 600 (7889), 536-542, 2021 | 52 | 2021 |
