| Design of protein-interaction specificity gives selective bZIP-binding peptides G Grigoryan, AW Reinke, AE Keating Nature 458 (7240), 859-864, 2009 | 365 | 2009 |
| Structural specificity in coiled-coil interactions G Grigoryan, AE Keating Current opinion in structural biology 18 (4), 477-483, 2008 | 360 | 2008 |
| De novo design of a transmembrane Zn2+-transporting four-helix bundle NH Joh, T Wang, MP Bhate, R Acharya, Y Wu, M Grabe, M Hong, ... Science 346 (6216), 1520-1524, 2014 | 312 | 2014 |
| Probing designability via a generalized model of helical bundle geometry G Grigoryan, WF DeGrado Journal of molecular biology 405 (4), 1079-1100, 2011 | 229 | 2011 |
| Computational design of virus-like protein assemblies on carbon nanotube surfaces G Grigoryan, YH Kim, R Acharya, K Axelrod, RM Jain, L Willis, M Drndic, ... Science 332 (6033), 1071-1076, 2011 | 222 | 2011 |
| Defining variant-resistant epitopes targeted by SARS-CoV-2 antibodies: A global consortium study KM Hastie, H Li, D Bedinger, SL Schendel, SM Dennison, K Li, ... Science 374 (6566), 472-478, 2021 | 205 | 2021 |
| Point-based probabilistic surfaces to show surface uncertainty G Grigoryan, P Rheingans IEEE Transactions on Visualization and Computer Graphics 10 (5), 564-573, 2004 | 172 | 2004 |
| A general-purpose protein design framework based on mining sequence–structure relationships in known protein structures J Zhou, AE Panaitiu, G Grigoryan Proceedings of the National Academy of Sciences 117 (2), 1059-1068, 2020 | 76 | 2020 |
| Structure-based prediction of bZIP partnering specificity G Grigoryan, AE Keating Journal of molecular biology 355 (5), 1125-1142, 2006 | 76 | 2006 |
| Identification of bZIP interaction partners of viral proteins HBZ, MEQ, BZLF1, and K-bZIP using coiled-coil arrays AW Reinke, G Grigoryan, AE Keating Biochemistry 49 (9), 1985-1997, 2010 | 74 | 2010 |
| Rapid search for tertiary fragments reveals protein sequence–structure relationships J Zhou, G Grigoryan Protein Science 24 (4), 508-524, 2015 | 73 | 2015 |
| Capture and imaging of a prehairpin fusion intermediate of the paramyxovirus PIV5 YH Kim, JE Donald, G Grigoryan, GP Leser, AY Fadeev, RA Lamb, ... Proceedings of the National Academy of Sciences 108 (52), 20992-20997, 2011 | 71 | 2011 |
| Protein-directed self-assembly of a fullerene crystal KH Kim, DK Ko, YT Kim, NH Kim, J Paul, SQ Zhang, CB Murray, ... Nature communications 7 (1), 11429, 2016 | 69 | 2016 |
| Probabilistic surfaces: Point based primitives to show surface uncertainty G Grigoryan, P Rheingans IEEE Visualization, 2002. VIS 2002., 147-153, 2002 | 67 | 2002 |
| Tertiary alphabet for the observable protein structural universe CO Mackenzie, J Zhou, G Grigoryan Proceedings of the National Academy of Sciences 113 (47), E7438-E7447, 2016 | 62 | 2016 |
| Illuminating protein space with a programmable generative model J Ingraham, M Baranov, Z Costello, V Frappier, A Ismail, S Tie, W Wang, ... BioRxiv, 2022.12. 01.518682, 2022 | 49 | 2022 |
| Ultra-fast evaluation of protein energies directly from sequence G Grigoryan, F Zhou, SR Lustig, G Ceder, D Morgan, AE Keating PLoS computational biology 2 (6), e63, 2006 | 49 | 2006 |
| Design of a heterospecific, tetrameric, 21-residue miniprotein with mixed α/β structure MH Ali, CM Taylor, G Grigoryan, KN Allen, B Imperiali, AE Keating Structure 13 (2), 225-234, 2005 | 47 | 2005 |
| Transmembrane Communication: General Principles and Lessons from the Structure and Function of the M2 Proton Channel, K+ Channels, and Integrin Receptors G Grigoryan, DT Moore, WF DeGrado Annual review of biochemistry 80, 211-237, 2011 | 38 | 2011 |
| Tertiary structural motif sequence statistics enable facile prediction and design of peptides that bind anti-apoptotic Bfl-1 and Mcl-1 V Frappier, JM Jenson, J Zhou, G Grigoryan, AE Keating Structure 27 (4), 606-617. e5, 2019 | 37 | 2019 |
William DeGradoUCSFVerified email at UCSF.edu
