| Intestinal ABCA1 directly contributes to HDL biogenesis in vivo LR Brunham, JK Kruit, J Iqbal, C Fievet, JM Timmins, TD Pape, ... The Journal of clinical investigation 116 (4), 1052-1062, 2006 | 647 | 2006 |
| Targeted inactivation of hepatic Abca1 causes profound hypoalphalipoproteinemia and kidney hypercatabolism of apoA-I JM Timmins, JY Lee, E Boudyguina, KD Kluckman, LR Brunham, A Mulya, ... The Journal of clinical investigation 115 (5), 1333-1342, 2005 | 602 | 2005 |
| β-cell ABCA1 influences insulin secretion, glucose homeostasis and response to thiazolidinedione treatment LR Brunham, JK Kruit, TD Pape, JM Timmins, AQ Reuwer, Z Vasanji, ... Nature medicine 13 (3), 340-347, 2007 | 469 | 2007 |
| Efflux and Atherosclerosis: The Clinical and Biochemical Impact of Variations in the ABCA1 Gene RR Singaraja, LR Brunham, H Visscher, JJP Kastelein, MR Hayden Arteriosclerosis, thrombosis, and vascular biology 23 (8), 1322-1332, 2003 | 356 | 2003 |
| Regulated cell death pathways in doxorubicin-induced cardiotoxicity E Christidi, LR Brunham Cell death & disease 12 (4), 339, 2021 | 299 | 2021 |
| A coding variant in RARG confers susceptibility to anthracycline-induced cardiotoxicity in childhood cancer F Aminkeng, AP Bhavsar, H Visscher, SR Rassekh, Y Li, JW Lee, ... Nature genetics 47 (9), 1079-1084, 2015 | 258 | 2015 |
| Differential effect of the rs4149056 variant in SLCO1B1 on myopathy associated with simvastatin and atorvastatin LR Brunham, PJ Lansberg, L Zhang, F Miao, C Carter, GK Hovingh, ... The pharmacogenomics journal 12 (3), 233-237, 2012 | 229 | 2012 |
| Optimizing cholesterol treatment in patients with muscle complaints RS Rosenson, S Baker, M Banach, KM Borow, LT Braun, E Bruckert, ... Journal of the American College of Cardiology 70 (10), 1290-1301, 2017 | 215 | 2017 |
| Variations on a Gene: Rare and Common Variants in ABCA1 and Their Impact on HDL Cholesterol Levels and Atherosclerosis LR Brunham, RR Singaraja, MR Hayden Annu. Rev. Nutr. 26, 105-129, 2006 | 188 | 2006 |
| Cholesterol in islet dysfunction and type 2 diabetes LR Brunham, JK Kruit, CB Verchere, MR Hayden The Journal of clinical investigation 118 (2), 403-408, 2008 | 183 | 2008 |
| Association of monogenic vs polygenic hypercholesterolemia with risk of atherosclerotic cardiovascular disease M Trinder, GA Francis, LR Brunham JAMA cardiology 5 (4), 390-399, 2020 | 179 | 2020 |
| HDL and LDL cholesterol significantly influence β-cell function in type 2 diabetes mellitus JK Kruit, LR Brunham, CB Verchere, MR Hayden Current opinion in lipidology 21 (3), 178-185, 2010 | 177 | 2010 |
| Global perspective of familial hypercholesterolaemia: a cross-sectional study from the EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC) AJ Vallejo-Vaz, CAT Stevens, ARM Lyons, KI Dharmayat, T Freiberger, ... The Lancet 398 (10312), 1713-1725, 2021 | 176 | 2021 |
| Reducing the clinical and public health burden of familial hypercholesterolemia: a global call to action KA Wilemon, J Patel, C Aguilar-Salinas, CD Ahmed, M Alkhnifsawi, ... JAMA cardiology 5 (2), 217-229, 2020 | 173 | 2020 |
| Modeling doxorubicin-induced cardiotoxicity in human pluripotent stem cell derived-cardiomyocytes A Maillet, K Tan, X Chai, SN Sadananda, A Mehta, J Ooi, MR Hayden, ... Scientific reports 6 (1), 25333, 2016 | 160 | 2016 |
| Accurate Prediction of the Functional Significance of Single Nucleotide Polymorphisms and Mutations in the ABCA1 Gene LR Brunham, RR Singaraja, TD Pape, A Kejariwal, PD Thomas, ... PLoS genetics 1 (6), e83, 2005 | 160 | 2005 |
| Specific loss of brain ABCA1 increases brain cholesterol uptake and influences neuronal structure and function JM Karasinska, F Rinninger, D Lütjohann, P Ruddle, S Franciosi, JK Kruit, ... Journal of Neuroscience 29 (11), 3579-3589, 2009 | 157 | 2009 |
| Risk of premature atherosclerotic disease in patients with monogenic versus polygenic familial hypercholesterolemia M Trinder, X Li, ML DeCastro, L Cermakova, S Sadananda, LM Jackson, ... Journal of the American College of Cardiology 74 (4), 512-522, 2019 | 147 | 2019 |
| Cholesterol efflux via ATP-binding cassette transporter A1 (ABCA1) and cholesterol uptake via the LDL receptor influences cholesterol-induced impairment of beta cell function … JK Kruit, PHC Kremer, L Dai, R Tang, P Ruddle, W de Haan, LR Brunham, ... Diabetologia 53, 1110-1119, 2010 | 142 | 2010 |
| Tissue-specific induction of intestinal ABCA1 expression with a liver X receptor agonist raises plasma HDL cholesterol levels LR Brunham, JK Kruit, TD Pape, JS Parks, F Kuipers, MR Hayden Circulation research 99 (7), 672-674, 2006 | 142 | 2006 |
